DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CSN1a and Gps1

DIOPT Version :9

Sequence 1:	NP_609720.1	Gene:	CSN1a / 34857	FlyBaseID:	FBgn0028838	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_006247928.1	Gene:	Gps1 / 117039	RGDID:	621532	Length:	536	Species:	Rattus norvegicus

Alignment Length:	347	Identity:	139/347 - (40%)
Similarity:	211/347 - (60%)	Gaps:	20/347 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 EETMLHLPSYADRYTDIPRLIRLKFIAQVCPELSVLALELALNHVKTTYNVKLYDELYKTLCVEV 69
            |...|.|..||..|:.:.|:.||:|||..||.|.|.||::||:.|:.|:||.:|:|:::.|. |.
  Rat    77 ENPTLDLEQYAASYSGLMRIERLQFIADRCPPLRVEALKMALSFVQRTFNVDMYEEIHRKLS-EA 140

  Fly    70 DRKYPNQSKGNEELHTTGGSEPSTSSGRGRVVVPYDSYWVEDNIMEATLMLQELDAELNFKKSNS 134
            .|:..|......|    .|.||.          |.|:.|||....:|.|.|::||.:|...|.||
  Rat   141 TRELQNAPDAIPE----SGVEPP----------PLDTAWVEATRKKALLKLEKLDTDLKNYKGNS 191

  Fly   135 GSSYVRRILEEIGDHHEKSGNLQMAVKFYARARPYCTSSENVINMFRNLIRVSIYMENWWHVLTY 199
            ....:||..:::|||:...|:|..|:|.|:|||.||||:::||||..|:|:||:|::||.|||:|
  Rat   192 IKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDYCTSAKHVINMCLNVIKVSVYLQNWSHVLSY 256

  Fly   200 IDEAKQYAYGFE-----NLAQEVPARLSCVAGLAHLGLKIYKSAAQYFLSTPYGRYDYDKIVAPE 259
            :.:|:......|     :..|.:..:|.|.||||.|..:.||.||:.||...:...|:.::::|.
  Rat   257 VSKAESTPEIAERGERDSQTQAILTKLKCAAGLAELAARKYKQAAKCFLLASFDHCDFPELLSPS 321

  Fly   260 DVTLYAGLCALATFDRETLQLNAINSEAFKPFFQLSPKMWTILAKFYAGEFDACMTLLREIENHV 324
            :|.:|.||||||||||:.||.|.|:|.:||.|.:|.|::..|:.|||..::.:|:.:|.|:::::
  Rat   322 NVAVYGGLCALATFDRQELQRNVISSSSFKLFLELEPQVRDIIFKFYESKYASCLKMLDEMKDNL 386

  Fly   325 RLDVYLSPHVSALYDLIMARML 346
            .||:||:|||..||..|..|.|
  Rat   387 LLDMYLAPHVRTLYTQIRNRAL 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CSN1a	NP_609720.1	RPN7	105..281	CDD:287560	77/180 (43%)
Gps1	XP_006247928.1	RPN7	162..343	CDD:287560	77/180 (43%)
Gps1	XP_006247928.1	PCI	358..462	CDD:279707	20/51 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0686
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D223526at33208
OrthoFinder	1	1.000	-	-		FOG0005242
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14145
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920