DRSC/TRiP Functional Genomics Resources

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Protein Alignment l(2)34Fc and FRRS1

DIOPT Version :10

Sequence 1:NP_609710.1 Gene:l(2)34Fc / 34838 FlyBaseID:FBgn0261534 Length:159 Species:Drosophila melanogaster
Sequence 2:NP_001013682.2 Gene:FRRS1 / 391059 HGNCID:27622 Length:626 Species:Homo sapiens


Alignment Length:159 Identity:45/159 - (28%)
Similarity:73/159 - (45%) Gaps:27/159 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 LAACLAI----SVHAYSDGAPKAACRDLTPQHGAKLQVTKPPYSISGPSH--------VRSDQKL 59
            |..|:.:    .|..|.:|....:|..:.|:||      ..|.|:  |.|        .|...::
Human     8 LGTCILLLHISYVANYPNGKVTQSCHGMIPEHG------HSPQSV--PVHDIYVSQMTFRPGDQI 64

  Fly    60 TLTLGGDEFLGFMIQARDGQN---RVVGQFQVVDSVHSQTLDCSG-KDDTITHLSAQKGKPLTGI 120
            .:||.|..|.||:::||:.::   ..:|.|.::||..||.|.|.. :...::|.||.|   .|.|
Human    65 EVTLSGHPFKGFLLEARNAEDLNGPPIGSFTLIDSEVSQLLTCEDIQGSAVSHRSASK---KTEI 126

  Fly   121 TFDWIPPAGYKGNVKFMATVVQTGFVYWV 149
            ...|..|:....:.:|:.|||:...:|||
Human   127 KVYWNAPSSAPNHTQFLVTVVEKYKIYWV 155

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
l(2)34FcNP_609710.1 Reeler 27..149 CDD:460411 38/133 (29%)
FRRS1NP_001013682.2 Reeler 32..155 CDD:460411 38/133 (29%)
DOMON_SDR_2_like 192..354 CDD:187686
Cyt_b561_FRRS1_like 320..533 CDD:176490
Blue background indicates that the domain is not in the aligned region.

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