Protein Alignment CG46301 and nol4lb

DIOPT Version :10

• Sequence 1: NP_001334737.1
• Gene: CG46301 / 34829
• FlyBaseID: FBgn0283651
• Length: 1237
• Species: Drosophila melanogaster
• Sequence 2: NP_001417770.1
• Gene: nol4lb / 791170
• ZFINID: ZDB-GENE-070112-1702
• Length: 703
• Species: Danio rerio
• Alignment Length: 1190
• Identity: 302/1190 - (25%)
• Similarity: 423/1190 - (35%)
• Gaps: 527/1190 - (44%)

  Fly    71 PTAEREIIYELFQPWALSTYGDQAKTKTITLRKKARILKALEGKE-------HSRPDSSKFRFWV 128
            |......::..||.|.|.||||..||||:|.||..:||:.|...:       .|...::||:|||
Zfish    16 PAVSEAEMFGDFQEWCLRTYGDSGKTKTVTRRKYNKILQTLLQSDDSEGVIIESNHINAKFKFWV 80

  Fly   129 KTKGFTTNRPEGFEEAPGSRRHLKNLPSSAILSDNPADVDLFAASTSKGFGRRTYRKVACVEEFF 193
            |:|||...|.|...|...:.|.:..:|..|...|.....|           ..:.::||.||:|:
Zfish    81 KSKGFQVGRSESENENGAADRPVLYVPIKATCVDGVLGPD-----------GSSLKRVAVVEDFY 134

  Fly   194 DIIYNVHMELG---GRSGMHAGQKRTYRIITETYAFLPREAVTRFLTICPECKKNLRPSSPSGGG 255
            ||||.:|:|:.   .::..|||||:||:.|.|||||||||||||||..|.||:|.:. .||||..
Zfish   135 DIIYAMHVEISSDPAKAPKHAGQKKTYKAIAETYAFLPREAVTRFLMSCGECQKRMH-ISPSGAE 198

  Fly   256 -KDSDLAGNESSSEVENYLNYSSH-TESSLEAGPTAKRRRHSSAEIKASLASGLAVGAGVASSMS 318
             |::    |:.||...:.::|:.. |.:.|:.........:...|                .|:|
Zfish   199 FKEN----NQPSSLAADLIDYNMPLTTTYLKQKKLQCMNNNEQDE----------------CSVS 243

  Fly   319 ATQLDVLWTGVPRSRSPKPPMAAEAAVETTPVSVPKIRIKTQLQRPSSPQDQSPADPNTDAQSQS 383
            :.:.|:                    .:.|.:|..:....:.|..|||      ||
Zfish   244 SEEFDM--------------------SDPTWISAERHGTLSDLNHPSS------AD--------- 273

  Fly   384 QIQSQSQSQSQSQSQSHSQPSGQGFDAQLLKSRDNLLRYYNFMRRFYAGEPVLAPPIYGSSLLQS 448
            ::.|...:..:....|.|: ||.|                |.:|       .|.||..|::.:..
Zfish   274 RMHSPQNAHKEEDDDSSSE-SGSG----------------NGIR-------TLTPPSVGAAGVND 314

  Fly   449 LSYPTTISTA-----ATATPTTPTTTTSAPGKMLAPPKTATPPPNPPKIKTSPDSLLRARTPPVA 508
            .:.|.:.|.|     :||.|...:||:|
Zfish   315 STGPGSGSYAEVNGNSTAAPLDFSTTSS------------------------------------- 342

  Fly   509 STATSAAPKDAAHTPINLTKSLFSSLKTGHAP-STSTPVPLKLELPSPPKPLPELRIPQLRGMPP 572
                |::.:|  ..|:||:..|..:|.|..|. :|.|           |:...|||    |..|
Zfish   343 ----SSSSED--QQPVNLSDRLSQALPTAAAMLATFT-----------PEHTEELR----RKYP- 385

  Fly   573 VELSLPLPPLDLERLKPITSTYLQLTRSMGLSDEDALRFDNLETIPATPVVSTDTASVVGVGVGG 637
                              .||.|:|.|.:.
Zfish   386 ------------------KSTELRLDRDIR----------------------------------- 397

  Fly   638 GGGAAAGAGGGAGGAGGLLGDVVSGLGGGLVNESEAYAGLMKDADKLKLMLLAWNYQNSTAVRNG 702
                                                                  :|.|.:
Zfish   398 ------------------------------------------------------DYNNKS----- 403

  Fly   703 TEGPDLSVVGGLWAQYQNALAQNAAAAAAASGKMDSSLSPVPRQDAHSPMETQDETNSSGQKEED 767
                         .||             :||..||....:..:|.     |...:.::...::|
Zfish   404 -------------PQY-------------SSGSYDSIKMEICAEDL-----TVGRSQAADDDDDD 437

  Fly   768 EVSEDDSDDKLDEKLATTHDPERLKAFNMFVRLFVDENLDRIIPISKQPKEKIQAIIDSCARQFP 832
            ....||| ||:::....  ||||||||||||||||||||||::||||||||||||||:||:||||
Zfish   438 HDDHDDS-DKINDVEGV--DPERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIESCSRQFP 499

  Fly   833 EFSDRSRKRIRTYLKSCRRNKKTRDGWENTTRPTPAHLTSVQAEQILAIACENESMN-AKRMRIG 896
            ||.:|:|||||||||||||.||  :|.|  |||||.||||..||.|||.|||:||.. |||||:.
Zfish   500 EFQERARKRIRTYLKSCRRMKK--NGME--TRPTPPHLTSAMAENILAAACESESRKAAKRMRMD 560

  Fly   897 L-----EPITHAVPAPGSAVAAAAAAAAAAAVVAATSSSAGGTSTTAAGNATATCGMGGVGDATG 956
            :     ||:             :...|.:...|:.|.
Zfish   561 VYQAHEEPV-------------SLDKAVSREPVSLTH---------------------------- 584

  Fly   957 LTSAAAAALPFVSAVGFARSTPNSEHADVLPFGGAGTAGGSGGGGAGGGGGGGMSSARSSPLALS 1021
                        ||...|.|..:.:...:           :||......|.||:.::...|:.|:
Zfish   585 ------------SAYSLAASAYSQDQLYI-----------NGGLNYSYRGYGGLCASMQHPVTLN 626

  Fly  1022 SNASVSGGASVTGLTLANGAGASNGAGLPASSPYTTDFSSPSTASPFVAAAAAVAAGRAPSYPGY 1086
            :..:.:.|
Zfish   627 TATAQTNG--------------------------------------------------------- 634

  Fly  1087 FPAVAGLGNVTPTDLSMKPTSGLGGNMVSNNNSNSSVTGNINSQLSAANLASLSNASNNNALVTA 1151
                       |||||||       ::.||::|:||                 |:...|
Zfish   635 -----------PTDLSMK-------SLASNSSSSSS-----------------SSLGRN------ 658

  Fly  1152 TQQLQQLQQQQQQQQQQQQQQQQQQLLVAGGGGMDGQSVRAPPILPHKLSANEVTAARQVISAYR 1216
                                          |||...|           ||..||.|.||:|:.||
Zfish   659 ------------------------------GGGASTQ-----------LSHTEVAAVRQLIAGYR 682

  Fly  1217 ESAAFLLRTADQVEQLLVQQ 1236
            ||||||||:||::|.|::||
Zfish   683 ESAAFLLRSADELENLILQQ 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG46301	NP_001334737.1	Integrase_H2C2	194..245	CDD:465569	32/53 (60%)
nol4lb	NP_001417770.1	Integrase_H2C2	<154..189	CDD:465569	26/34 (76%)