Protein Alignment rk and lrit3a

DIOPT Version :10

• Sequence 1: NP_476702.1
• Gene: rk / 34819
• FlyBaseID: FBgn0003255
• Length: 1360
• Species: Drosophila melanogaster
• Sequence 2: NP_001122166.1
• Gene: lrit3a / 558559
• ZFINID: ZDB-GENE-080723-63
• Length: 636
• Species: Danio rerio
• Alignment Length: 370
• Identity: 82/370 - (22%)
• Similarity: 144/370 - (38%)
• Gaps: 74/370 - (20%)

  Fly   142 SICERWLQKHCHC--------TGSLEVLRLSCRGIGILAVPVNLPNEVVVLDLGNNNLTKLEANS 198
            |:.:.:....|.|        |||..||   |....:..:|||:|.:.|.|.:....:.::...:
Zfish    15 SVAQPFCPSQCTCVYHGRSDGTGSRSVL---CNDPDMSDIPVNVPLDTVKLRVEKTAVRRVPTEA 76

  Fly   199 FFMAPNLEELTLSDNSIINMDPNAFYGLAKLKRLSLQNCGLKSLPPQSFQGLAQLTSLQLNGNAL 263
            |:....|..|.::.|||.::||.:||.|..|..|.|....:.:.|.:|.:.:..|.:|.|:.|.|
Zfish    77 FYYLSELRYLWITYNSITSVDPGSFYNLKVLHELRLDGNMIATFPWESLKEMPSLKTLDLHNNRL 141

  Fly   264 VSLDGDCLGHLQKLRTLRLEGNLFYRIPTNAL------AGLRTLEALNLGSNLLTIINDEDFP-- 320
            .|:..:...:|..:..|.:..|....:|::.:      :|::.    :..::..|::..:|.|
Zfish   142 TSVPVEAAPYLINITYLDISSNKLTTLPSDLVDIWPPFSGIQP----SANTSQKTVLGLQDNPWY 202

  Fly   321 ---RMPNLIVLLLKRNQIMKISAGALKNLTALKVLELDDNLISSLPEGLS-KLSQLQELSITSNR 381
               |:..||               .|..:..:.|:.:|..|..|.||.|| .|.|..||......
Zfish   203 CDCRISKLI---------------ELSKMAGIPVVLMDQVLTCSGPEHLSGVLFQRAELDQCVKP 252

  Fly   382 LRWINDTEL--PRSMQML---DMRANPLSTI-----------------SPGAFRGMS----KLRK 420
            ....:.|::  |....:|   |....|..|:                 |||  .|:.    .|..
Zfish   253 TVMTSATKITSPLGSNVLLRCDANGFPTPTLLWTTADGSVVNNTVVQESPG--EGVRWSILSLHS 315

  Fly   421 LILSDVRTLRSFPELEACHALEILKLDRAGIQEV----PANLCRQ 461
            ::..|....|...:..|.:|...:.|...|:|..    |.|:.:|
Zfish   316 IVFKDAGDYRCKAKNVAGNAEAYITLSVDGVQPTTPFPPINITKQ 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rk	NP_476702.1	LRR	<157..390	CDD:443914	57/244 (23%)
		leucine-rich repeat	158..179	CDD:275380	6/20 (30%)
		leucine-rich repeat	183..204	CDD:275380	2/20 (10%)
		leucine-rich repeat	205..228	CDD:275380	10/22 (45%)
		leucine-rich repeat	229..252	CDD:275380	5/22 (23%)
		leucine-rich repeat	253..276	CDD:275380	7/22 (32%)
		leucine-rich repeat	277..300	CDD:275380	4/28 (14%)
		LRR	292..612	CDD:443914	41/212 (19%)
		leucine-rich repeat	301..324	CDD:275380	4/27 (15%)
		leucine-rich repeat	325..348	CDD:275380	3/22 (14%)
		leucine-rich repeat	349..371	CDD:275380	9/22 (41%)
		leucine-rich repeat	372..393	CDD:275380	4/22 (18%)
		leucine-rich repeat	394..415	CDD:275380	7/40 (18%)
		leucine-rich repeat	418..486	CDD:275380	11/48 (23%)
		leucine-rich repeat	441..464	CDD:275378	6/25 (24%)
		leucine-rich repeat	487..510	CDD:275380
		leucine-rich repeat	511..534	CDD:275380
		leucine-rich repeat	535..558	CDD:275380
		leucine-rich repeat	559..580	CDD:275380
		7tmA_Glyco_hormone_R	754..1028	CDD:320264
		TM helix 1	755..781	CDD:320264
		TM helix 2	788..813	CDD:320264
		TM helix 3	833..863	CDD:320264
		TM helix 4	875..897	CDD:320264
		TM helix 5	918..947	CDD:320264
		TM helix 6	956..986	CDD:320264
		TM helix 7	996..1021	CDD:320264
lrit3a	NP_001122166.1	LRR	<74..>172	CDD:443914	26/97 (27%)
		leucine-rich repeat	83..106	CDD:275378	10/22 (45%)
		leucine-rich repeat	107..130	CDD:275378	5/22 (23%)
		leucine-rich repeat	131..154	CDD:275378	7/22 (32%)
		leucine-rich repeat	155..168	CDD:275378	2/12 (17%)
		leucine-rich repeat	191..203	CDD:275378	3/11 (27%)
		LRRCT	199..249	CDD:214507	17/64 (27%)
		Ig_3	251..330	CDD:464046	13/80 (16%)