Protein Alignment rk and lrrc4b

DIOPT Version :10

• Sequence 1: NP_476702.1
• Gene: rk / 34819
• FlyBaseID: FBgn0003255
• Length: 1360
• Species: Drosophila melanogaster
• Sequence 2: NP_001096358.1
• Gene: lrrc4b / 100124949
• XenbaseID: XB-GENE-5945982
• Length: 641
• Species: Xenopus tropicalis
• Alignment Length: 319
• Identity: 90/319 - (28%)
• Similarity: 140/319 - (43%)
• Gaps: 49/319 - (15%)

  Fly   250 LAQLTSLQLNGNALVSLDGDCLGHLQKLRTLRLEGNLFYRIPTNALAGLRTLEALNLGSNLLTII 314
            |..:|||.|.|.:..|....|....|..|.......|. .:|.:.....|   .|||..|::.:|
 Frog    26 LLWVTSLALGGISPTSCPAACTCSNQASRVACTRRELM-EVPESISVNTR---YLNLQENIIQVI 86

  Fly   315 NDEDFPRMPNLIVLLLKRNQIMKISAGALKNLTALKVLELDDNLISSLP-EGLSKLSQLQELSIT 378
            ..:.|..:.:|.:|.|.:|.|.||..||...|..|..|||.||.::::| :....||:|:||
 Frog    87 KTDTFKHLRHLEILQLSKNLIRKIEVGAFNGLPNLSTLELFDNRLTTVPTQAFEYLSKLREL--- 148

  Fly   379 SNRLRWINDTELPRSMQMLDMRANPLSTISPGAFRGMSKLRKLILSDVRTLRSFPELEACHALEI 443
                 |              :|.||:.:|...||..:..||:|.|.:::.|....|.    |.|.
 Frog   149 -----W--------------LRNNPIESIPSYAFNRVPSLRRLDLGELKKLEYISEA----AFEG 190

  Fly   444 LKLDRAGIQEVPANLCRQTPRLKSLELKTNSLKRIPNLSSCRDLRLLDLSSNQIEKIQGKPFNGL 508
            |                  ..|:.|.|...:||.||||::...|..|:||.|::|.|:...|.||
 Frog   191 L------------------VNLRYLNLGMCNLKDIPNLTALVRLEELELSGNRLEMIRPGSFQGL 237

  Fly   509 KQLNDLLLSYNRIKALPQDAFQGIPKLQLLDLEGNEISYIHKEAFSGFTALEDLNLGNN 567
            ..|..|.|.:..:..:.::||..:..|:.|:|..|.:..:..:.|:....||.::|.:|
 Frog   238 TSLRKLWLMHAHVTIIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHN 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rk	NP_476702.1	LRR	<157..390	CDD:443914	42/140 (30%)
		leucine-rich repeat	158..179	CDD:275380
		leucine-rich repeat	183..204	CDD:275380
		leucine-rich repeat	205..228	CDD:275380
		leucine-rich repeat	229..252	CDD:275380	1/1 (100%)
		leucine-rich repeat	253..276	CDD:275380	7/22 (32%)
		leucine-rich repeat	277..300	CDD:275380	3/22 (14%)
		LRR	292..612	CDD:443914	78/277 (28%)
		leucine-rich repeat	301..324	CDD:275380	6/22 (27%)
		leucine-rich repeat	325..348	CDD:275380	10/22 (45%)
		leucine-rich repeat	349..371	CDD:275380	8/22 (36%)
		leucine-rich repeat	372..393	CDD:275380	4/20 (20%)
		leucine-rich repeat	394..415	CDD:275380	6/20 (30%)
		leucine-rich repeat	418..486	CDD:275380	18/67 (27%)
		leucine-rich repeat	441..464	CDD:275378	2/22 (9%)
		leucine-rich repeat	487..510	CDD:275380	10/22 (45%)
		leucine-rich repeat	511..534	CDD:275380	5/22 (23%)
		leucine-rich repeat	535..558	CDD:275380	5/22 (23%)
		leucine-rich repeat	559..580	CDD:275380	4/9 (44%)
		7tmA_Glyco_hormone_R	754..1028	CDD:320264
		TM helix 1	755..781	CDD:320264
		TM helix 2	788..813	CDD:320264
		TM helix 3	833..863	CDD:320264
		TM helix 4	875..897	CDD:320264
		TM helix 5	918..947	CDD:320264
		TM helix 6	956..986	CDD:320264
		TM helix 7	996..1021	CDD:320264
lrrc4b	NP_001096358.1	LRRNT	42..75	CDD:214470	6/36 (17%)
		LRR	<72..319	CDD:443914	78/272 (29%)
		leucine-rich repeat	73..96	CDD:275380	7/25 (28%)
		leucine-rich repeat	97..120	CDD:275380	10/22 (45%)
		leucine-rich repeat	121..144	CDD:275380	8/22 (36%)
		leucine-rich repeat	145..168	CDD:275380	10/44 (23%)
		leucine-rich repeat	169..193	CDD:275380	9/45 (20%)
		leucine-rich repeat	194..215	CDD:275380	9/20 (45%)
		leucine-rich repeat	216..239	CDD:275380	10/22 (45%)
		leucine-rich repeat	240..263	CDD:275380	5/22 (23%)
		leucine-rich repeat	264..285	CDD:275380	5/20 (25%)
		LRRCT	296..346	CDD:214507	1/1 (100%)
		I-set	349..438	CDD:400151
		Ig strand B	366..370	CDD:409353
		Ig strand C	378..382	CDD:409353
		Ig strand E	404..408	CDD:409353
		Ig strand F	418..423	CDD:409353
		Ig strand G	431..434	CDD:409353