Protein Alignment NimC1 and Megf11

DIOPT Version :10

• Sequence 1: NP_001260453.1
• Gene: NimC1 / 34816
• FlyBaseID: FBgn0259896
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_038938374.1
• Gene: Megf11 / 691517
• RGDID: 1582797
• Length: 1139
• Species: Rattus norvegicus
• Alignment Length: 889
• Identity: 208/889 - (23%)
• Similarity: 280/889 - (31%)
• Gaps: 342/889 - (38%)

  Fly    29 NDCSHPESVPYNRKVLKSKLVPFQQYSYFH-----GWVTKYRHQYVYEDETAYRTVM------RP 82
            |.|||.||  |...|.:|...||.|..|..     .|....||:..|  :||||..:      |.
  Rat    26 NVCSHWES--YAVTVQESYAHPFDQIYYTRCADILNWFKCTRHRISY--KTAYRRGLRTMYRRRS 86

  Fly    83 SCCEGYEGSVENCKPVCRQQCPQHGFCSSPNTCSCNAGYGGIDCHPVCPT-----------VCGK 136
            .||.||..:.:.|.|:|.::| .||.|.||:||.|..|:||.||...|.:           .|..
  Rat    87 QCCPGYYENGDFCIPLCTEEC-MHGRCVSPDTCHCEPGWGGPDCSSGCDSEHWGPHCSNRCQCQN 150

  Fly   137 NEFCDR-PGVCSCQNGYKRTSPSDNCLP-----VCEKECG-HHSFCSEP--GKCECEPGYEKVGN 192
            ...|:. .|.|.|..|::.....:.|.|     .|:..|. ||....:|  |:|.|.|||..|..
  Rat   151 GALCNPITGACVCAPGFRGWRCEEFCAPGTHGKGCQLLCQCHHGASCDPRTGECLCAPGYTGVYC 215

  Fly   193 GTVFPDGYKNNSNG-NCSPICPKDCGQNSRCVR-PGVCECENGYAG---------DDGGTNCRPV 246
            ..:.|.|    |:| :|...||  |.....|.. .|.|.|..|:.|         ...|.||...
  Rat   216 EELCPPG----SHGAHCELRCP--CQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQD 274

  Fly   247 CSTCPENGLC-LSPGVCVCKPGYVMRNDLCQPHCE------KCSDNAHC-------VAPNQCECF 297
            | .|...|.| ...|.|.|..||:  .|.||..|.      :||....|       .|...|||.
  Rat   275 C-PCHHGGQCDHVTGQCHCTAGYM--GDRCQEECPFGTFGFRCSQRCDCHNGGQCSPATGACECE 336

  Fly   298 PGYESSGADKKCVPK--------------------------------------CSKGCTNGF--- 321
            |||:.....::..|:                                      |::.|..|:
  Rat   337 PGYKGPSCQERLCPEGLHGPGCTSPCPCDTENTISCHPVTGACTCQPGWSGHYCNESCPAGYYGN 401

  Fly   322 -CFAPET-------------CVCSIGYQMGPNQVCE---------PKCSLNC----------VHG 353
             |..|.|             |.|:.|: ||  :||.         |.||..|          |.|
  Rat   402 GCQLPCTCQNGADCHSITGSCTCAPGF-MG--EVCAVPCAAGTYGPNCSSVCSCSNGGTCSPVDG 463

  Fly   354 KCTSPE-------------------------------------TCTCDPGY-------------- 367
            .||..|                                     :|.|.||:
  Rat   464 SCTCREGWQGLDCSLPCPSGTWGLNCNESCVCANGAACSPFDGSCACTPGWLGDSCELPCPDGTF 528

  Fly   368 -----RFKDNSHHE-CDPI--------------CDSGCSNGHCVAPN---FCICHDGYQLNSTNP 409
                 ...|.||.: |||:              |||.|..|.. .||   .|.|.:|   .|.:|
  Rat   529 GLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRW-GPNCSVSCSCENG---GSCSP 589

  Fly   410 VTSMCQ-------PICK----------GC---------QFGDC-VAPNVCECNVGYENINGLCEL 447
            |...|:       |:|:          ||         ..|.| ....:|||..|:.  ..||.
  Rat   590 VDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSRGPCHHVSGICECLPGFS--GALCN- 651

  Fly   448 QTTTDSYEYSTTTVELQS-------STVDPQLQ--------TSTSEVP---------HS-NCTAG 487
            |.....: :.....:|.|       |.:|...|        ..:...|         |: :|..|
  Rat   652 QVCAGGH-FGQDCAQLCSCANNGTCSPIDGSCQCFPGWTGKDCSQACPSGFWGSACFHTCSCHNG 715

  Fly   488 CMCWIEYDG--------MGTFNTAKCAKICVDPQDKPCLNLDNCQ----CDLSSGQLVCQEDSDM 540
            ..|..| ||        .|.|.|.:|.....   .|.|.::..||    ||..:|:..|:    .
  Rat   716 ASCSAE-DGACHCTPGWTGLFCTQRCPAAFF---GKDCGHICQCQNGASCDHITGKCTCR----T 772

  Fly   541 DYSGENSR---------YVCHILPE--------------------QGARSEAEVRIPDRTGSSNK 576
            .:||.:..         |.|..|.|                    :|.|.:....:.|......|
  Rat   773 GFSGRHCEQRCAPGTFGYGCQQLCECMNNATCDHVTGTCYCSPGFKGIRCDQAALMMDELNPYTK 837

  Fly   577 WMIIVGS---CAGMIIGV------AATIIGIKYYRRSTSRRNFE 611
            ....:|:   ..|.:.|:      ...::|:..:||   ||..|
  Rat   838 ISPALGAERHSVGAVTGIILLLFLVVVLLGLFAWRR---RRQKE 878

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NimC1	NP_001260453.1	None
Megf11	XP_038938374.1	EMI	25..94	CDD:462204	26/71 (37%)
		EGF_CA	189..234	CDD:473889	18/50 (36%)
		Laminin_EGF	275..320	CDD:395007	15/47 (32%)