Protein Alignment NimC1 and DKK2

DIOPT Version :10

• Sequence 1: NP_001260453.1
• Gene: NimC1 / 34816
• FlyBaseID: FBgn0259896
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_055236.1
• Gene: DKK2 / 27123
• HGNCID: 2892
• Length: 259
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 57/260 - (21%)
• Similarity: 85/260 - (32%)
• Gaps: 79/260 - (30%)

  Fly   314 SKGCTNGFCFAPETCVCSIGYQMGPNQVCEPKCSLN--CVHGK-CTSPE--TCTCDPGYRFKDNS 373
            |.|...|..|.        |.:.|.|......||.:  |..|: |.||.  :..|....|.|...
Human    54 SAGMYQGLAFG--------GSKKGKNLGQAYPCSSDKECEVGRYCHSPHQGSSACMVCRRKKKRC 110

  Fly   374 HHE--CDPICDSGCSNGHCVAPNFCICHDGYQLNSTNPVTSMCQ----PICKGCQFGDCVAPNVC 432
            |.:  |.|  .:.|:||.|:                 |||....    |...|.:..|....:..
Human   111 HRDGMCCP--STRCNNGICI-----------------PVTESILTPHIPALDGTRHRDRNHGHYS 156

  Fly   433 ECNVGYENINGLCELQTTTDSYEYSTTTVELQSSTVDPQLQTSTSEVPHSNCTAGCMC----WIE 493
            ..::|::|:.            ...|....::....||.|::       |:|..|..|    |
Human   157 NHDLGWQNLG------------RPHTKMSHIKGHEGDPCLRS-------SDCIEGFCCARHFW-- 200

  Fly   494 YDGMGTFNTAKC------AKICVDPQDKPCLNLDNCQ-CDLSSGQLVCQEDSDMDYSGENSRYVC 551
                    |..|      .::|...:.|....|:..| ||.:.| |.|:...|..||.:...:||
Human   201 --------TKICKPVLHQGEVCTKQRKKGSHGLEIFQRCDCAKG-LSCKVWKDATYSSKARLHVC 256

  Fly   552  551
            Human   257  256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NimC1	NP_001260453.1	None
DKK2	NP_055236.1	Dkk2_Cys1	74..128	CDD:438009	16/55 (29%)
		DKK-type Cys-1	78..127		16/50 (32%)
		Dkk2_Cys2	175..258	CDD:437999	24/100 (24%)
		DKK-type Cys-2	183..256		20/90 (22%)