Protein Alignment NimC1 and DKK3

DIOPT Version :10

• Sequence 1: NP_001260453.1
• Gene: NimC1 / 34816
• FlyBaseID: FBgn0259896
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001317149.1
• Gene: DKK3 / 27122
• HGNCID: 2893
• Length: 364
• Species: Homo sapiens
• Alignment Length: 349
• Identity: 70/349 - (20%)
• Similarity: 99/349 - (28%)
• Gaps: 133/349 - (38%)

  Fly   176 SEPGKCECEPGYE-------KVGNGT--VFPDGYK--NNSNG---------------------NC 208
            ||.......|.|.       ||||.|  |..:.:|  ||..|                     .|
Human    83 SEVNLANLPPSYHNETNTDTKVGNNTIHVHREIHKITNNQTGQMVFSETVITSVGDEEGRRSHEC 147

  Fly   209 SPICPKDCGQNSRCVRPG---VCECENGYAGDDGGTNCRPVCSTCPENGLCLSPGVCVCKPGYVM 270
              |..:|||.:..|....   .|:            .||.....|..:..|....:||
Human   148 --IIDEDCGPSMYCQFASFQYTCQ------------PCRGQRMLCTRDSECCGDQLCV------- 191

  Fly   271 RNDLCQPHCEKCSDNAH--CVAPNQCECFPGYESSGADKKCVPKCSKGCTNGFCFAPETCVCSIG 333
                 ..||.|.:....  .:..||.:|.|                     |.|.|
Human   192 -----WGHCTKMATRGSNGTICDNQRDCQP---------------------GLCCA--------- 221

  Fly   334 YQMGPNQVCEPKCSLNCVHGKCTSPETCTCDPGYRFKDNSHHECDPICDSGCSNGHCVAPNFCIC 398
            :|.|   :..|.|:...|.|     |.|. ||..|..|....|.:|  |.......|.:...|..
Human   222 FQRG---LLFPVCTPLPVEG-----ELCH-DPASRLLDLITWELEP--DGALDRCPCASGLLCQP 275

  Fly   399 HDGYQLN-------STNPVTSMCQPICKGC--QFGDCVAPNVCECNVGYENINGLCELQTTTDSY 454
            |...:|.       .::.:..:|:|...|.  |.|:.:.|                  :...|.|
Human   276 HRLPRLEPGFVPSLPSHSLVYVCKPTFVGSRDQDGEILLP------------------REVPDEY 322

  Fly   455 EYSTTTVELQSSTVDPQLQTSTSE 478
            |..:...|::....|  |:.|.:|
Human   323 EVGSFMEEVRQELED--LERSLTE 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NimC1	NP_001260453.1	None
DKK3	NP_001317149.1	Dkk3_N_Cys1	41..196	CDD:438008	28/138 (20%)
		Dkk3_Cys2	199..278	CDD:438000	25/119 (21%)