Protein Alignment NimC1 and DKK1

DIOPT Version :10

• Sequence 1: NP_001260453.1
• Gene: NimC1 / 34816
• FlyBaseID: FBgn0259896
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_036374.1
• Gene: DKK1 / 22943
• HGNCID: 2891
• Length: 266
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 63/296 - (21%)
• Similarity: 87/296 - (29%)
• Gaps: 99/296 - (33%)

  Fly   119 AGYGGIDCHPVCPTVCGKNEFCDRPGVCSCQNGYKRTSPSDNCLPVCEKECGHHSFCSEPGKCEC 183
            |..||   ||:.             ||.:..|....::...|..|......||      ||..
Human    19 AALGG---HPLL-------------GVSATLNSVLNSNAIKNLPPPLGGAAGH------PGSA-- 59

  Fly   184 EPGYEKVGNGTVFPDGYKNNSNGNCSPI-CPKD--CGQNSRCVRPGVCECENGYAGDDGGTNCRP 245
                .....|.::|.|.|..:..|..|. |.:|  ||.:..|..|        ..|.|.|..
Human    60 ----VSAAPGILYPGGNKYQTIDNYQPYPCAEDEECGTDEYCASP--------TRGGDAGVQ--- 109

  Fly   246 VCSTC-PENGLCLSPGVCVCKPGYVMRNDLCQPHCEKCSDNAHCVAPNQCECFPG------YESS 303
            :|..| .....|:...:| | ||...:|.:|     ..||..|         |.|      .||.
Human   110 ICLACRKRRKRCMRHAMC-C-PGNYCKNGIC-----VSSDQNH---------FRGEIEETITESF 158

  Fly   304 GADKKCVPKCS------------KGCTNGFCFAPETCV----CSIGYQMGPNQVCEPKCSLNCVH 352
            |.|...:...|            ||.....|.....|.    |:..:.   :::|:|......|
Human   159 GNDHSTLDGYSRRTTLSSKMYHTKGQEGSVCLRSSDCASGLCCARHFW---SKICKPVLKEGQV- 219

  Fly   353 GKCTSP-----------ETCTCDPGYRFK-DNSHHE 376
              ||..           :.|.|..|...: ...||:
Human   220 --CTKHRRKGSHGLEIFQRCYCGEGLSCRIQKDHHQ 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NimC1	NP_001260453.1	None
DKK1	NP_036374.1	Dkk1_N_Cys1	16..139	CDD:438010	38/165 (23%)
		DKK-type Cys-1	85..138		17/65 (26%)
		Dkk1_Cys2	182..264	CDD:437998	15/78 (19%)
		DKK-type Cys-2	189..263		13/71 (18%)