Protein Alignment NimC1 and Megf11

DIOPT Version :10

• Sequence 1: NP_001260453.1
• Gene: NimC1 / 34816
• FlyBaseID: FBgn0259896
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001395541.1
• Gene: Megf11 / 214058
• MGIID: 1920951
• Length: 1138
• Species: Mus musculus
• Alignment Length: 889
• Identity: 207/889 - (23%)
• Similarity: 278/889 - (31%)
• Gaps: 342/889 - (38%)

  Fly    29 NDCSHPESVPYNRKVLKSKLVPFQQYSYFH-----GWVTKYRHQYVYEDETAYRTVM------RP 82
            |.|||.||  |...|.:|...||.|..|..     .|....||:..|  :||||..:      |.
Mouse    25 NVCSHWES--YAVTVQESYAHPFDQIYYTRCADILNWFKCTRHRISY--KTAYRRGLRTMYRRRS 85

  Fly    83 SCCEGYEGSVENCKPVCRQQCPQHGFCSSPNTCSCNAGYGGIDCHPVCPT-----------VCGK 136
            .||.||..:.:.|.|:|.::| .||.|.||:||.|..|:||.||...|.:           .|..
Mouse    86 QCCPGYYENGDFCIPLCTEEC-MHGRCVSPDTCHCEPGWGGPDCSSGCDSEHWGPHCSNRCQCQN 149

  Fly   137 NEFCDR-PGVCSCQNGYKRTSPSDNCLP-----VCEKECG-HHSFCSEP--GKCECEPGYEKVGN 192
            ...|:. .|.|.|..|::.....:.|.|     .|:..|. ||....:|  |:|.|.|||..|..
Mouse   150 GALCNPITGACVCAPGFRGWRCEELCAPGTHGKGCQLLCQCHHGASCDPRTGECLCAPGYTGVYC 214

  Fly   193 GTVFPDGYKNNSNG-NCSPICPKDCGQNSRCVR-PGVCECENGYAG---------DDGGTNCRPV 246
            ..:.|.|    |:| :|...||  |.....|.. .|.|.|..|:.|         ...|.||...
Mouse   215 EELCPPG----SHGAHCELRCP--CQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQD 273

  Fly   247 CSTCPENGLC-LSPGVCVCKPGYVMRNDLCQPHCE------KCSDNAHC-------VAPNQCECF 297
            | .|...|.| ...|.|.|..||:  .|.||..|.      .||....|       .|...|||.
Mouse   274 C-PCHHGGQCDHVTGQCHCTAGYM--GDRCQEECPFGTFGFLCSQRCDCHNGGQCSPATGACECE 335

  Fly   298 PGYESSGADKKCVPK--------------------------------------CSKGCTNGF--- 321
            |||:.....::..|:                                      |::.|..|:
Mouse   336 PGYKGPSCQERLCPEGLHGPGCTLPCPCDTENTISCHPVTGACTCQPGWSGHYCNESCPAGYYGN 400

  Fly   322 -CFAPET-------------CVCSIGYQMGPNQVCE---------PKCSLNC----------VHG 353
             |..|.|             |.|:.|: ||  :||.         |.||..|          |.|
Mouse   401 GCQLPCTCQNGADCHSITGSCTCAPGF-MG--EVCAVPCAAGTYGPNCSSVCSCSNGGTCSPVDG 462

  Fly   354 KCTSPE-------------------------------------TCTCDPGY-------------- 367
            .||..|                                     :|.|.||:
Mouse   463 SCTCREGWQGLDCSLPCPSGTWGLNCNETCICANGAACSPFDGSCACTPGWLGDSCELPCPDGTF 527

  Fly   368 -----RFKDNSHHE-CDPI--------------CDSGCSNGHCVAPN---FCICHDGYQLNSTNP 409
                 ...|.||.: |||:              |||.|..|.. .||   .|.|.:|   .|.:|
Mouse   528 GLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRW-GPNCSVSCSCENG---GSCSP 588

  Fly   410 VTSMCQ-------PICKG-CQFG----DCVAP---------------NVCECNVGYENINGLCEL 447
            ....|:       |:|:. |..|    .|..|               .:|||..|:.  ..||.
Mouse   589 EDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSRGPCHHISGICECLPGFS--GALCN- 650

  Fly   448 QTTTDSYEYSTTTVELQS-------STVDPQLQ--------TSTSEVP---------HS-NCTAG 487
            |.....: :.....:|.|       |.:|...|        ..:...|         |: :|..|
Mouse   651 QVCAGGH-FGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPSGFWGSACFHTCSCHNG 714

  Fly   488 CMCWIEYDG--------MGTFNTAKCAKICVDPQDKPCLNLDNCQ----CDLSSGQLVCQEDSDM 540
            ..|..| ||        .|.|.|.:|.....   .|.|.::..||    ||..:|:..|:    .
Mouse   715 ASCSAE-DGACHCTPGWTGLFCTQRCPSAFF---GKDCGHICQCQNGASCDHITGKCTCR----T 771

  Fly   541 DYSGENSR---------YVCHILPE--------------------QGARSEAEVRIPDRTGSSNK 576
            .:||.:..         |.|..|.|                    :|.|.:....:.|......|
Mouse   772 GFSGRHCEQRCAPGTFGYGCQQLCECMNNATCDHVTGTCYCSPGFKGIRCDQAALMMDELNPYTK 836

  Fly   577 WMIIVGS---CAGMIIGV------AATIIGIKYYRRSTSRRNFE 611
            ....:|:   ..|.:.|:      ...::|:..:||   ||..|
Mouse   837 ISPALGAERHSVGAVTGIVLLLFLVVVLLGLFAWRR---RRQKE 877

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NimC1	NP_001260453.1	None
Megf11	NP_001395541.1	EMI	24..93	CDD:462204	26/71 (37%)
		EGF_CA	188..233	CDD:473889	18/50 (36%)
		EGF_CA	274..319	CDD:473889	15/47 (32%)