DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hacd2 and Hacd1

DIOPT Version :9

Sequence 1:	NP_609655.2	Gene:	Hacd2 / 34762	FlyBaseID:	FBgn0032524	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	NP_609534.1	Gene:	Hacd1 / 34614	FlyBaseID:	FBgn0032394	Length:	245	Species:	Drosophila melanogaster

Alignment Length:	234	Identity:	70/234 - (29%)
Similarity:	109/234 - (46%)	Gaps:	13/234 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 GYIKEKT--KKVYMIFYNLAMFVGYLYIMVVMGVLYYRDGVDSIGKT----YANVGNAFKFIQLL 199
            |..||.:  .|:|:..||....||:.||:..:...|...|.:...:.    |..:  |....|..
  Fly    13 GASKEPSAVTKLYLFAYNAGQVVGWSYILWQLVNYYILQGPEFRAQVTLWEYTRL--AVIIFQNA 75

  Fly   200 QYLEVMHPMFGYTKGSPVVPFFQVSGRNFILFLMIDMEPRMYAKPVVFYVFIIWSLVELVRYPYY 264
            .::|:::..||..|.:|||..|||..|..::..::...|.....|.:....:.|::.|::||.||
  Fly    76 AFVEILNASFGLVKSNPVVTGFQVFSRMMVVVGVVMATPTGKVSPGLPIALLAWAITEIIRYGYY 140

  Fly   265 LAQLLGREVGLLTWLRYTIWIPLYPMGILCEGIIVLRNIPYIEETKRFTVEMPNPWNITFDMVLF 329
            ...::......:.:||||.:|.|||:|:..|.:.......|..|...::|.|||.||.||....|
  Fly   141 ALNIVKVVPHFVVFLRYTTFIVLYPIGVTGELLCFWWAQSYARENSVWSVVMPNKWNATFSYFGF 205

  Fly   330 LKIYLM--LLIIPGSYLVMSHMAKLRSKKLGKGRAKRQQ 366
            |.|.::  :.|.|..||   ||...|.|.||.|.:...|
  Fly   206 LWIVMLGYIPIFPQLYL---HMFAQRRKILGGGSSGSPQ 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hacd2	NP_609655.2	p23_hB-ind1_like	6..114	CDD:107222
Hacd2	NP_609655.2	PTPLA	197..357	CDD:282269	51/161 (32%)
Hacd1	NP_609534.1	PTPLA	73..232	CDD:282269	51/161 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456185
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5198
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1458293at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11035
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850