DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hacd2 and SPBC19C2.15c

DIOPT Version :9

Sequence 1:	NP_609655.2	Gene:	Hacd2 / 34762	FlyBaseID:	FBgn0032524	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	NP_595700.1	Gene:	SPBC19C2.15c / 2540685	PomBaseID:	SPBC19C2.15c	Length:	208	Species:	Schizosaccharomyces pombe

Alignment Length:	222	Identity:	57/222 - (25%)
Similarity:	102/222 - (45%)	Gaps:	30/222 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 YMIFYNLAMFVGYLYIMVVMGVLYYRDGV-DSIGKTYANVGNAFKFIQLLQYLEVMHPMFGYTKG 214
            |:..||:.....::.:::..|:::   |: ......:.......:::|.|...||.|.:||....
pombe     9 YLKLYNVISCFLWMSVLLRTGLIW---GITKDTAVVFHETNTLVRWVQTLAIAEVFHSIFGLVSS 70

  Fly   215 SPVVPFFQVSGRNFILFLMIDMEPRMY---AKPVVFYVFIIWSLVELVRYPYYLAQLLGREVGLL 276
            ||:....||:.|.::::.:  ..|..|   ..|:...:.|.||:.|::||.:|...|.|.....|
pombe    71 SPLTTIIQVASRLYLVWGV--CYPFSYVIEGSPIYLSMIIAWSITEIIRYAFYAFNLNGDIPAFL 133

  Fly   277 TWLRYTIWIPLYPMGILCEGIIVLRN---IPYIEETKRFTVEMPNPWNITFDMVLFLKIYLMLLI 338
            |||||..::.|||:|...|.::||::   ..|:....:..      |.|           ||.:.
pombe   134 TWLRYNTFLILYPIGAGSEFLLVLKSRIAAQYVWSLNKLL------WPI-----------LMSIY 181

  Fly   339 IPGSYLVMSHMAKLRSKKLGKGRAKRQ 365
            .||.|::.:||...| :|:.|..|.|:
pombe   182 PPGLYIMYTHMLAQR-RKISKRAAARR 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hacd2	NP_609655.2	p23_hB-ind1_like	6..114	CDD:107222
Hacd2	NP_609655.2	PTPLA	197..357	CDD:282269	48/165 (29%)
SPBC19C2.15c	NP_595700.1	Ptpl	1..208	CDD:227525	57/222 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5198
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770