DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hacd2 and hpo-8

DIOPT Version :9

Sequence 1:	NP_609655.2	Gene:	Hacd2 / 34762	FlyBaseID:	FBgn0032524	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	NP_504740.2	Gene:	hpo-8 / 188513	WormBaseID:	WBGene00020517	Length:	218	Species:	Caenorhabditis elegans

Alignment Length:	223	Identity:	68/223 - (30%)
Similarity:	116/223 - (52%)	Gaps:	14/223 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 KVYMIFYNLAMFVGYLYIMV--VMGVLYYRDGVDSIGKTYANVGNAFKFIQLLQYLEVMHPMFGY 211
            :.|::.||:...:|:..|:|  |:|:   .:|: :..:.|.:|....|..|....|||:|.:.|.
Worm     4 QTYLVAYNVLQILGWSAILVKTVLGL---ANGL-TWPQLYESVEFELKIFQTAAILEVIHAIVGL 64

  Fly   212 TKGSPV-VPFFQVSGRNFILFLMIDMEPRMYAKPVVFYVFIIWSLVELVRYPYYLAQLLGREVG- 274
            .: ||| ....||:.|..:::.::.:.........|..:.:.||:.|::||.:|...:|.:.:.
Worm    65 VR-SPVGTTAMQVTSRVVLVWPILHLCSTARFSIGVPLLLVAWSVTEVIRYSFYALSVLKQPIPY 128

  Fly   275 LLTWLRYTIWIPLYPMGILCEGIIVLRNIPYIEETKRFTVEMPNPWN--ITFDMVLFLKIYLMLL 337
            .|.:||||::..|||||:..|.:.:..::..::|.|..|:||||..|  |:|..||   |...|.
Worm   129 FLLYLRYTLFYVLYPMGVSGELLTLFASLNEVDEKKILTLEMPNRLNMGISFWWVL---IIAALS 190

  Fly   338 IIPGSYLVMSHMAKLRSKKLGKGRAKRQ 365
            .|||...:..:|...|.|.||.|..|:|
Worm   191 YIPGFPQLYFYMIGQRKKILGGGSKKKQ 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hacd2	NP_609655.2	p23_hB-ind1_like	6..114	CDD:107222
Hacd2	NP_609655.2	PTPLA	197..357	CDD:282269	51/163 (31%)
hpo-8	NP_504740.2	PTPLA	50..210	CDD:282269	51/163 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5198
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1458293at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820