DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hacd2 and AgaP_AGAP003815

DIOPT Version :9

Sequence 1:	NP_609655.2	Gene:	Hacd2 / 34762	FlyBaseID:	FBgn0032524	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	XP_310376.5	Gene:	AgaP_AGAP003815 / 1271555	VectorBaseID:	AGAP003815	Length:	235	Species:	Anopheles gambiae

Alignment Length:	223	Identity:	82/223 - (36%)
Similarity:	116/223 - (52%)	Gaps:	11/223 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 KVYMIFYNLAMFVGYLYIMVVMGVLYYRDGVDSIGKTYANVGNAFKFIQLLQYLEVMHPMFGYTK 213
            |.|:..||.|.|.|:.||.|.. :.::.....|:...::.||.|..|.|:|..|||:|.|.|...
Mosquito    14 KGYLTLYNTAQFAGWTYIFVQF-IQHFAVHGQSLDTLWSRVGQATFFFQMLAILEVVHAMVGIVP 77

  Fly   214 GSPVVPFFQVSGRNFILFLMIDMEPRMYAKPVVFYVFIIWSLVELVRYPYYLAQLLGREV-GLLT 277
            .:..:.|.||.||..|:...|:..|.....|.:......|||.|::||.||:|.||...| .||.
Mosquito    78 SNVAMTFLQVFGRCMIVAGAIEGTPTGQKSPGLPLALFCWSLTEIIRYSYYVAHLLLPAVPSLLV 142

  Fly   278 WLRYTIWIPLYPMGILCEGIIVLRNIPYIEETKRFTVEMPNPWNITFDMVLFLKIYLMLL----I 338
            ||||||:||:||.|.|.|.:.......||.:|.:::||:||.:|.:|....|  |::|.:    :
Mosquito   143 WLRYTIFIPMYPCGFLGELLCSYWAQSYIRDTGKWSVELPNRFNFSFSFYYF--IWIMAVCYMPL 205

  Fly   339 IPGSYLVMSHMAKLRSKKLGKGRAKRQQ 366
            .|..||   ||...|.|..|:|...||:
Mosquito   206 FPQMYL---HMFAQRRKVFGRGTQTRQK 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hacd2	NP_609655.2	p23_hB-ind1_like	6..114	CDD:107222
Hacd2	NP_609655.2	PTPLA	197..357	CDD:282269	63/164 (38%)
AgaP_AGAP003815	XP_310376.5	PTPLA	61..221	CDD:282269	63/164 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5198
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1458293at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.780