DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hacd2 and AgaP_AGAP003814

DIOPT Version :9

Sequence 1:	NP_609655.2	Gene:	Hacd2 / 34762	FlyBaseID:	FBgn0032524	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	XP_310375.4	Gene:	AgaP_AGAP003814 / 1271554	VectorBaseID:	AGAP003814	Length:	231	Species:	Anopheles gambiae

Alignment Length:	224	Identity:	70/224 - (31%)
Similarity:	109/224 - (48%)	Gaps:	9/224 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 KVYMIFYNLAMFVGYLYIMVVMGVLYYRDGVDSIGKTYANVGNAFKFIQLLQYLEVMHPMFGYTK 213
            |.|:|.||.|..||:.|::..: :.||.....:....:..:|......|....||::|.......
Mosquito    11 KSYLILYNAAQVVGWCYMLYQL-IAYYTIDKGTEKTLWDYLGFTVILFQNAALLEIVHAFTRIVP 74

  Fly   214 GSPVVPFFQVSGRNFILFLMIDMEPRMYAKPVVFYVFIIWSLVELVRYPYYLAQLLGREVGLLTW 278
            .:||:..|||..|..::..::...|.....|.:....:.||:.|::||.||...|:.....||.:
Mosquito    75 SNPVITTFQVLSRVMVVCGVVMATPTGKVSPGLPLAILAWSVTEIIRYAYYALNLIDAVPQLLIF 139

  Fly   279 LRYTIWIPLYPMGILCEGIIVLRNIPYIEETKRFTVEMPNPWNITFDMVLFLKIYLMLLI--IPG 341
            ||||.:|.|||.|:..|.:.......::..||::::||||.:|.||..:.||...::|.|  .|.
Mosquito   140 LRYTTFIVLYPTGVTGELLCFFWAQSHVASTKQWSIEMPNTYNFTFSYLYFLWAVMLLYIPLFPQ 204

  Fly   342 SYLVMSHMAKLRSKKLGKGR---AKRQQH 367
            .||   ||...|.|.||.|.   |.:|:|
Mosquito   205 LYL---HMFAQRKKILGSGSSSGATKQKH 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hacd2	NP_609655.2	p23_hB-ind1_like	6..114	CDD:107222
Hacd2	NP_609655.2	PTPLA	197..357	CDD:282269	52/161 (32%)
AgaP_AGAP003814	XP_310375.4	PTPLA	58..217	CDD:282269	52/161 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5198
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1458293at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.780