DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tehao and MstProx

DIOPT Version :10

Sequence 1:NP_477438.1 Gene:Tehao / 34761 FlyBaseID:FBgn0026760 Length:795 Species:Drosophila melanogaster
Sequence 2:NP_649719.2 Gene:MstProx / 40890 FlyBaseID:FBgn0015770 Length:965 Species:Drosophila melanogaster


Alignment Length:1025 Identity:237/1025 - (23%)
Similarity:390/1025 - (38%) Gaps:355/1025 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 TFCLGLSPQC-------TCAAEGNVVRFHCPDEYAMLLEVSEPGASLYMSYYASTELQW-LPRFN 85
            |:|.|:   |       ||..|  ...:...:||.:::....            .|:.| :|..|
  Fly    14 TYCGGI---CNDTVASKTCDRE--AYDYIATNEYHLIMRDGH------------LEVNWKIPDPN 61

  Fly    86 ISSLVKIEFDAYIFWPEKFLS---------DLLKTLGVQTVKTIIFRDRTLETVVTRDVLNSGNG 141
            |..:..|..:..:...|..:|         |.|:.|||:||.....:..:.: |:.|||      
  Fly    62 IFIISPISKENRLKLNELIVSDTSYPIRAVDYLRQLGVETVTRFENQINSFK-VIERDV------ 119

  Fly   142 YMETSQPENITTWHFGSVPGLKKFK-------FFSHVPE--------LQESIFHGFDTLRDLHLS 191
                         |:  :.|.|..|       :.:.:.|        :.|.|.:.:.|:.:..::
  Fly   120 -------------HY--INGPKSLKIIIQSNLYLNEIIEYINKTTDNVNEIIINAYKTVENQQIA 169

  Fly   192 VNVTTLPGNMLSTVNGTLKTLT-----IESPGIVSFG-----------NPLLRELQQLRNLSLAL 240
            ::      |::......|::||     ||:.....|.           |..:|.|..||.|..:|
  Fly   170 LD------NLIFNGKSHLRSLTFIGFQIENLSTKPFAQFINLKRMVLTNCTVRNLTFLRTLQKSL 228

  Fly   241 IHPFHERDKQLQPHFFGSMTNLEEVRL----------ASATSSVNRSMFKGTNKLQLIKMNG--- 292
            .|...:.|.::...:|.:.::|:.:::          |...:..|.:..:|.|.|:..|:..   
  Fly   229 EHLELDIDNEVDLKYFTNFSSLKFMKVRNYIPNKNFTALICTHKNCNFIRGINGLECPKLCQCLY 293

  Fly   293 -NDDLMELPGEIFLDQVNLKTLDL---------------SCNAIVTLHEDVFKGLGNLTLLDLSK 341
             .|||     |:.:|..||..|.:               |.|::..|......|...:..||:|:
  Fly   294 IIDDL-----ELNIDCSNLGLLQIPPLPIPSYGGVKLNFSNNSLSQLPTMTLPGYKLVKRLDVSR 353

  Fly   342 NRLTNLSST-------------------------------IF-------------APLTSLNVLR 362
            |||||||..                               ||             .||  ||..|
  Fly   354 NRLTNLSINHLPAKLDYLDVSFNEIINMGNDVIKYLRTVPIFKQTGNQWTIHCDDKPL--LNFFR 416

  Fly   363 LNK---------------NSLTAMSPSVFQDVVSLNYIEM-VNTQFYGATLLMNYEAVVCT---- 407
            ..|               :|||.: |..|...:..::|.: |..|.|   .|:|.|.::.:    
  Fly   417 HLKLIIRMKSAEMKPMFLHSLTEL-PKGFLKFLGKHFIWLGVRKQEY---YLINEEQLLQSMHRK 477

  Fly   408 ----NDEACQYKSAEW----------------------QCDPRCICWVQRSVGSLIVDCRGTSLE 446
                |.....||..||                      .|..:|.|...|....|.:|||...:.
  Fly   478 LNNLNTIMSIYKYMEWLHRKLIFVNREYDLFYIRQMAAPCPHKCECCYSRDSLILKIDCRNKFVY 542

  Fly   447 ELPDLPRTTLLSTVLKVGNNSLTSLPTVSEHSGYANVSG---LFLSDNNLTSLGSGDQLPDNLTH 508
            ..||:           |..|        |...|..|:|.   |.||.||::::... .||..|..
  Fly   543 NFPDI-----------VARN--------SRLMGKQNMSSPMELHLSKNNISNITIA-MLPKELRF 587

  Fly   509 LDVRGNQIQSLSDEFLLFLQEPNNTMTLSLSGNPITCGCESLSLLFFVR---------------- 557
            ||:|.|.:.:|.|:.|.:|::  |::...|||||..|.|:|.|:|..:|                
  Fly   588 LDLRFNNLVTLDDKVLSYLKK--NSIKTKLSGNPWNCDCKSRSVLSILRDHEPLEYDVTLKRCNI 650

  Fly   558 ----------------------------------------------------------------- 557
                                                                             
  Fly   651 SPTDCPDVCVCCLDNLTWPSFIVDCRGEGLLQMPSLSSRVTYVDLRNNNLTALSQKNRSSIENRS 715

  Fly   558 ------TNP------------------QRVRDIADIVCTKQKKSFQQMEAFELCPSYVLLISCVV 598
                  .||                  ..:.|..:|.|:..:| ...:....:|||.:.....:.
  Fly   716 LKLHLLDNPWSCSCNDIEKINFMKSVSSSIVDFTEIKCSNGEK-LVSINQHIVCPSDLFYYLALA 779

  Fly   599 GGLVIVICLLTVFYLMFQQELKIWLYNNNLCLWWVSEEELDKDKTYDAFISYSHKDEELISKLLP 663
            ..||..|..|. |.:.|:|.:.:|.|.:.:||...::.||||||.:|||::::||||.|:.:.:.
  Fly   780 ISLVATIIALN-FLIWFRQPVLVWFYEHGVCLSLSAKRELDKDKRFDAFLAFTHKDEALLEEFVD 843

  Fly   664 KLESGPHPFRLCLHDRDWLVGDCIPEQIVRTVDDSKRVIIVLSQHFIDSVWARMEFRIAYQATLQ 728
            :||.|...|:||.:.||||.|:.||:.|.:::.||:|:|::::::|::|.|.|:|||:|..||.:
  Fly   844 RLERGRPRFQLCFYLRDWLAGESIPDCIGQSIKDSRRIIVLMTENFMNSTWGRLEFRLALHATSR 908

  Fly   729 DKRKRIIIILYRELEHMNGIDSELRAYLKLNTYLKWGDPLFWSKLYYAMP 778
            |:.||:|::||..:::.:.:|||||.|:..||||:...|.||:||.|:||
  Fly   909 DRCKRLIVVLYPNVKNFDSLDSELRTYMAFNTYLERSHPNFWNKLIYSMP 958

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TehaoNP_477438.1 LRR 184..>541 CDD:443914 107/494 (22%)
leucine-rich repeat 185..207 CDD:275380 1/21 (5%)
leucine-rich repeat 209..232 CDD:275380 9/38 (24%)
leucine-rich repeat 233..261 CDD:275380 7/27 (26%)
leucine-rich repeat 262..284 CDD:275380 4/31 (13%)
leucine-rich repeat 285..309 CDD:275380 7/27 (26%)
leucine-rich repeat 310..333 CDD:275380 6/37 (16%)
leucine-rich repeat 334..357 CDD:275380 14/66 (21%)
leucine-rich repeat 358..381 CDD:275380 9/37 (24%)
leucine-rich repeat 445..482 CDD:275380 6/36 (17%)
leucine-rich repeat 483..505 CDD:275380 8/24 (33%)
TIR 643..779 CDD:214587 60/136 (44%)
MstProxNP_649719.2 PRK15370 <315..>398 CDD:185268 16/82 (20%)
leucine-rich repeat 325..345 CDD:275378 4/19 (21%)
leucine-rich repeat 346..367 CDD:275378 10/20 (50%)
TIR 823..960 CDD:214587 60/136 (44%)

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