Protein Alignment Tehao and CD180

DIOPT Version :10

• Sequence 1: NP_477438.1
• Gene: Tehao / 34761
• FlyBaseID: FBgn0026760
• Length: 795
• Species: Drosophila melanogaster
• Sequence 2: NP_005573.2
• Gene: CD180 / 4064
• HGNCID: 6726
• Length: 661
• Species: Homo sapiens
• Alignment Length: 139
• Identity: 28/139 - (20%)
• Similarity: 46/139 - (33%)
• Gaps: 43/139 - (30%)

  Fly   809 GTPEYVSPEIIL---NKGH--------DRAVDYWALGVLIHELLVGKPPFRGKNHMKTYNAI--- 859
            |:|:|::|...|   ||..        :.|..||.                      :|.::
Human    64 GSPDYLTPTTFLETENKAKFSISPIQWNNAGQYWC----------------------SYRSLTNK 106

  Fly   860 LRGIDIIELPSRVPKKAQVLIKRLCRQTAAERLGYGKNGIADIKNHPWFGSFEWQKLKER---TM 921
            ||..||:||........:|.:..|.......    |:|......:...:..|...|..|:   .|
Human   107 LRQSDIMELVVTGVILGEVTLSALPSYVVTS----GRNVTLQCASQVVYDRFILMKEDEKFSTAM 167

  Fly   922 PAPLIRPIV 930
            |:..|.|::
Human   168 PSWKIYPVL 176

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tehao	NP_477438.1	LRR	184..>541	CDD:443914
		leucine-rich repeat	185..207	CDD:275380
		leucine-rich repeat	209..232	CDD:275380
		leucine-rich repeat	233..261	CDD:275380
		leucine-rich repeat	262..284	CDD:275380
		leucine-rich repeat	285..309	CDD:275380
		leucine-rich repeat	310..333	CDD:275380
		leucine-rich repeat	334..357	CDD:275380
		leucine-rich repeat	358..381	CDD:275380
		leucine-rich repeat	445..482	CDD:275380
		leucine-rich repeat	483..505	CDD:275380
		TIR	643..779	CDD:214587
CD180	NP_005573.2	LRR	<38..310	CDD:443914	28/139 (20%)
		leucine-rich repeat	38..57	CDD:275380
		LRR 1	54..75		4/10 (40%)
		leucine-rich repeat	58..78	CDD:275380	5/13 (38%)
		LRR 2	78..99		5/42 (12%)
		leucine-rich repeat	79..102	CDD:275380	6/44 (14%)
		LRR 3	102..123		6/20 (30%)
		leucine-rich repeat	103..126	CDD:275380	6/22 (27%)
		LRR 4	126..147		3/24 (13%)
		leucine-rich repeat	127..150	CDD:275380	3/26 (12%)
		LRR 5	150..171		5/20 (25%)
		leucine-rich repeat	151..174	CDD:275380	6/22 (27%)
		LRR 6	174..195		1/3 (33%)
		leucine-rich repeat	175..195	CDD:275380	0/2 (0%)
		leucine-rich repeat	196..234	CDD:275380
		LRR 7	201..221
		LRR_11	221..249	CDD:408601
		leucine-rich repeat	235..275	CDD:275380
		LRR	<275..553	CDD:443914
		LRR 8	275..296
		leucine-rich repeat	276..299	CDD:275380
		LRR 9	299..320
		leucine-rich repeat	300..322	CDD:275380
		LRR 10	322..343
		leucine-rich repeat	323..371	CDD:275380
		LRR 11	346..366
		LRR 12	371..391
		leucine-rich repeat	372..397	CDD:275380
		LRR 13	397..418
		leucine-rich repeat	398..421	CDD:275380
		LRR 14	421..442
		leucine-rich repeat	422..446	CDD:275380
		LRR 15	446..466
		leucine-rich repeat	447..470	CDD:275380
		LRR 16	470..493
		leucine-rich repeat	471..497	CDD:275380
		LRR 17	497..518
		leucine-rich repeat	498..521	CDD:275380
		LRR 18	521..544
		leucine-rich repeat	522..543	CDD:275380
		LRR 19	546..564
		PCC	549..>626	CDD:188093