Protein Alignment Tehao and Tlr10

DIOPT Version :10

• Sequence 1: NP_477438.1
• Gene: Tehao / 34761
• FlyBaseID: FBgn0026760
• Length: 795
• Species: Drosophila melanogaster
• Sequence 2: NP_001139507.2
• Gene: Tlr10 / 305355
• RGDID: 1311569
• Length: 811
• Species: Rattus norvegicus
• Alignment Length: 885
• Identity: 187/885 - (21%)
• Similarity: 317/885 - (35%)
• Gaps: 267/885 - (30%)

  Fly    66 ASLYMSY--YASTELQWLPR----------FNISSLVKI-------------------EF---DA 96
            :|:|..|  ..||| .|.||          ::..:|.|:                   :|   |.
  Rat     5 SSIYTLYNIIMSTE-AWAPRPTDERELISNYSNMALRKVPPDVTPATTILDLSYNLLYQFQSSDC 68

  Fly    97 YIFWPEKFLSDLLKTLGVQTVKTIIFRDRTLETVVTRDVLNSGNGYMETS--QPENITTW----- 154
            :.|...:||  :|....:|.:.|.||.            ||....|::.|  :.::| ||
  Rat    69 HSFSKLRFL--ILCHNSIQQLDTKIFD------------LNKELSYLDLSYNRLQSI-TWSSLVD 118

  Fly   155 ---------HFGSVPGLKKFKFFSHV------------PELQE-------SIFHGFDTLRD---- 187
                     .|.::|..::.....|:            .:||:       ::|.|.:||..
  Rat   119 LRHLDLSFNDFDTLPACEEIGNMRHLETLGLSGAKIQRSDLQKIANLQFSTVFIGLNTLSHYEEG 183

  Fly   188 ---------LHLSVNVTTLPGNM---------------LSTVNGTLKTLTIESPGIVSFGNPLLR 228
                     ||:   |..:..|.               :|.:.|..:.::.|:|..:|..|....
  Rat   184 SLPVLNTTVLHI---VLPMAANFWVLLCDGMKTSKVVEMSNIGGKSQFVSYETPRTLSVENTKAS 245

  Fly   229 EL--QQLRNLSLALIHPFH------ERDKQLQPHFFGSMTNLEE--------VRLASATSSVN-R 276
            .|  .::..|...|:|.|.      ....|:|...||.|.:.:.        |..|....|:: |
  Rat   246 TLIFHKVDLLWDDLLHVFQFVWRTSVECFQIQDLTFGGMASRDHSSFDYSNTVMKAVILESIHFR 310

  Fly   277 SMFKGTNKLQLIKMNGNDDLMELPGEIFLDQVNLKTLDLS---------------------CNAI 320
            ..|...||:.|                |..|::|:.|.:|                     .|.|
  Rat   311 IFFIPQNKIYL----------------FFTQMDLENLTISDAQMPHLLFPSHPQSFQHLNFANNI 359

  Fly   321 VTLHEDVFKG---LGNLTLLDLSKNRLTNLS-STIFAPLTSLNVLRLNKNSLTAMSPSVFQDVVS 381
            :|  :|:||.   :..|..|.|..|:|..|| .::||..|||..|.|::|.|
  Rat   360 LT--DDLFKNPIQMPYLKTLVLRGNQLETLSLVSLFANHTSLLHLDLSQNLL------------- 409

  Fly   382 LNYIEMVNTQFYGATLLMNYEAVVCTNDEACQYKSAEWQCDPRCICWVQRSVGSLIVDCRGTSLE 446
                     |.......|..:.::..|..:.::..:.::|.|:.|
  Rat   410 ---------QHGNGEKCMWPDTLILLNLSSNKFDGSVFRCLPKSI-------------------- 445

  Fly   447 ELPDLPRTTLLSTVLKVGNNSLTSLPTVSEHSGYANVSGLFLSDNNLTSLGSGDQLPDNLTHLDV 511
                        ..|.:.||.:.::|  .|.....::..|.::.|.||.|...|.. ..|:.|::
  Rat   446 ------------QTLDLNNNKIRAVP--KEIIYLKSLRELSIAFNFLTDLPGCDHF-KQLSSLNI 495

  Fly   512 RGNQIQSLSDEFLLFLQEPNNTMTLSLSGNPITCGCESLSLLFFVRTNPQRVRDIADIVCTKQKK 576
            ..|.|.|.|.:|....||   ..||:...||..|.||....::..:.:...:....|....:...
  Rat   496 EMNLILSPSLDFFQSCQE---VKTLNAGRNPFRCICEFRDFIWLEKHSKGLMSGWPDSYACEYPL 557

  Fly   577 SFQQMEAFEL------CPSYVLLISCV----VGGLVIVICLLTVFYLMFQQELKIWLYNNNLCLW 631
            |.:.....::      |.:.:|:::.|    |.|||:..|:|....|.:.:.|...:...:....
  Rat   558 SLKGTPLKDVYLPELACNTTLLIVTIVLVILVLGLVVAFCILKFDMLWYLRVLAQCIRTQHRIRK 622

  Fly   632 WVSEEELDKDKTYDAFISYSHKDEELI-SKLLPKLESGPHPFRLCLHDRDWLVGDCIPEQIVRTV 695
            .|.||. .:...:.|||||:..|...: ::|:|.||:......|||.:|::.....|.|.|:...
  Rat   623 TVREER-KRSIQFHAFISYAAHDSVWVKNELIPNLETEDGSVLLCLPERNFDPDRSIAENIISCT 686

  Fly   696 DDSKRVIIVLSQHFIDSVWARMEFRIAYQATLQDKRKRIIIILYRELEHMNGIDS--------EL 752
            :.|.:.|.|||.:|:.:.|...|..:|:....:|....||.||      :..|.|        :|
  Rat   687 EKSYKSIFVLSPNFVQNGWCHNELYLAHHNPFRDNYDYIIPIL------LEPIPSYCVPTKFPKL 745

  Fly   753 RAYLKLNTYLKWGDP-----LFWSKLYYAMPHNRRVLKGQ 787
            :|.|:...||:|...     |||:.|..|:..|....:|:
  Rat   746 KALLEKKVYLEWPKDRRKHGLFWANLRAAINVNLSDTRGR 785

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tehao	NP_477438.1	LRR	184..>541	CDD:443914	85/426 (20%)
		leucine-rich repeat	185..207	CDD:275380	6/49 (12%)
		leucine-rich repeat	209..232	CDD:275380	5/24 (21%)
		leucine-rich repeat	233..261	CDD:275380	9/33 (27%)
		leucine-rich repeat	262..284	CDD:275380	5/30 (17%)
		leucine-rich repeat	285..309	CDD:275380	3/23 (13%)
		leucine-rich repeat	310..333	CDD:275380	9/46 (20%)
		leucine-rich repeat	334..357	CDD:275380	9/23 (39%)
		leucine-rich repeat	358..381	CDD:275380	5/22 (23%)
		leucine-rich repeat	445..482	CDD:275380	5/36 (14%)
		leucine-rich repeat	483..505	CDD:275380	6/21 (29%)
		TIR	643..779	CDD:214587	44/149 (30%)
Tlr10	NP_001139507.2	None