Protein Alignment Uvrag and uvrag

DIOPT Version :10

• Sequence 1: NP_609632.1
• Gene: Uvrag / 34735
• FlyBaseID: FBgn0032499
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: XP_002941209.2
• Gene: uvrag / 100486296
• XenbaseID: XB-GENE-488174
• Length: 698
• Species: Xenopus tropicalis
• Alignment Length: 723
• Identity: 165/723 - (22%)
• Similarity: 262/723 - (36%)
• Gaps: 235/723 - (32%)

  Fly    13 LATQQLRLRNLNRIQGFNIESWPHEKSLELDDPDDVLLYYTLH---TDKASEAFYTSEKLPQRHQ 74
            |.|||.|||:|..|...||.:....:.|:        .|:|||   ..|....||.|
 Frog    42 LHTQQRRLRHLRNIAARNIVNKNGYRLLD--------TYFTLHLCDEKKIYREFYKS-------- 90

  Fly    75 QQKWAEICTD--DEAWRK-----------TNAQCVCVKVWKHYSAERRDGQPPEVEQRHKDVFGR 126
                 |:..|  :..||.           |:..|..|::|.                      |:
 Frog    91 -----EVVKDSLNPTWRSLDFGLMPDRLDTSVSCFVVRIWG----------------------GK 128

  Fly   127 SQLTPSRLPRPPELLFSWGVYFSGLIPLSPLTLSQCGRNCLVFQLNGEQFASPSMISEQALQSQL 191
            :.:.        .||..|.|...||..:.| .:..|..|.::|.||...:.:       |.:|:.
 Frog   129 NDVC--------RLLIEWKVNLDGLKYIGP-QIHACNPNEIIFGLNDGYYGA-------AFESKN 177

  Fly   192 HLHYQKYAEEEKLEEPQDEGINSPAVSRSSSPVLRMSTMRYAQLKCQRQEIRRSNNLEKLLTLQR 256
            |...|                                  |.:.|:..:..:|.|..:..||.|.|
 Frog   178 HSELQ----------------------------------RNSHLQVDQSAVRNSYGVFSLLRLHR 208

  Fly   257 LQRLHQQKRRQMAEVCREI---ARLSVHCVTRNELRLKPRTTSLS----GDYSAHQYHSMGRALS 314
            .|...:|.:..:.::.:||   .||:..|   |||:.:.....|.    .|....|..|:||.:.
 Frog   209 AQCAIKQTQVTVLKIGKEIEEKLRLTSSC---NELKKESECLRLKILVLQDELERQKKSLGREME 270

  Fly   315 VLLAEQQQIAPLTLYNAQQLTRRIEALSSQQRLLKAERETFRQRNERTRQLLKEMREQREAQQWE 379
            :|..||:                  .|:.::.:...:||..:::||...:|.||...:||
 Frog   271 ILQKEQR------------------LLNDRRNVFNVDREKLQKQNETLGELRKECTAKRE----- 312

  Fly   380 LHSQRHRLEKERLELRTLAPQHLEQRDQKRQIERQVERRMSTLVLELQEIYNIQNVGGRQFSICG 444
                                       |..:...|:..|...|:.||..||.::....:.:.|||
 Frog   313 ---------------------------QFLKTNAQLTIRCRQLLSELSYIYPVEAPDQKDYFICG 350

  Fly   445 IAFPHMEQYTSESRQAANAQLLDNVSPLAVSAALGYVAHLVQMLAIIMDRPLRNRILYEPSKARI 509
            :..|:.|.:          |..|:.|   |:.||||.||||.|::..:..|||..||::.|::.|
 Frog   351 VKLPNSEDF----------QAKDDGS---VAVALGYTAHLVSMISFFLQVPLRYPILHKGSRSAI 402

  Fly   510 VDDIKE-LTYTTREFPLYTRSILPSQQTKYAIYLLRQNVSQLCFDIT-GQCDLRNTFGNLLELFS 572
            .|:|.: ||...||||||.:. ....|..|.:|||.:|::||.:..: |..|||.|..||
 Frog   403 KDNINDKLTEKEREFPLYPKG-GEKLQFDYGVYLLNKNIAQLRYQYSLGTPDLRQTLPNL----- 461

  Fly   573 TLRYIERTQRDEVDERDGTAVGAGCGEARLANGLTAPHLSQSHSSVDM-----NHVPLP-TGVN- 630
             ..::|.          |..|  .|....:::.:..|....|.:.|..     :..|.| .|:.
 Frog   462 -KTFLEH----------GLMV--RCDRHHMSSAIPVPRRPTSSTFVSQDVGFSSRTPTPDKGLRK 513

  Fly   631 --AVKDALLQQLLPP-----GVSEALAIEGYASTQRICRSVGSYSDGEDEFRPRLEHNYSNSDSN 688
              :.::...|...||     .::|.:||...|.              |.|.||..    |:.|::
 Frog   514 RASSENENTQYKTPPPSYKAALAEPIAILVPAK--------------EPEKRPVA----SSLDAS 560

  Fly   689 ITLQTERS 696
            :.:..|.|
 Frog   561 VNISKEAS 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uvrag	NP_609632.1	ATG14	329..552	CDD:462986	61/223 (27%)
uvrag	XP_002941209.2	VPS38	46..447	CDD:435943	130/560 (23%)