Protein Alignment CG44085 and spa2

DIOPT Version :10

• Sequence 1: NP_001260440.1
• Gene: CG44085 / 34732
• FlyBaseID: FBgn0264894
• Length: 2381
• Species: Drosophila melanogaster
• Sequence 2: NP_594077.1
• Gene: spa2 / 2543517
• PomBaseID: SPAC3G9.05
• Length: 659
• Species: Schizosaccharomyces pombe
• Alignment Length: 780
• Identity: 142/780 - (18%)
• Similarity: 260/780 - (33%)
• Gaps: 274/780 - (35%)

  Fly   843 RSFKILQAMTTPE--------NADHKIHTELDSDLENVELNE-----SPNNNNNNNNNSNNGSTE 894
            |.::.|.....||        ||:.:...:|.. |.:::.:|     :.......||:.......
pombe     7 RQYRFLARYLEPEFVKDPALRNANARPREKLQR-LSHIQFSELLTDVADELQRRINNDPKVRFLP 70

  Fly   895 NNNNYNNKINSKTNKRHSYTSSTPTSSPSTCTDP--TIHSSNSSLSSD--SSCPPQPPRSQSVPP 955
            ..::|:.|.|   :.|...:|..||.....|.|.  .:.|..|....:  |:.||...|:.|.||
pombe    71 PVDSYHPKRN---HARQKLSSLAPTRLRDLCMDVFFEVQSRYSGALKEVSSNTPPNMTRAASQPP 132

  Fly   956 QYPYAFGYPYPWYMPPPPPVNGEGAPWPYPYSYPPPPPPQSIDGKQAEGFPPYPYYYPYYPPPLP 1020
                                                                             
pombe   133 ----------------------------------------------------------------- 132

  Fly  1021 PYGQQPGEAQIPPGYPQFHAMPPYGHPYPYPVAPSYSQSSTEESRASSVLPDIIITPSTDDIPSQ 1085
                           ||...:|        ..||.:...|:..:.::|:.|....|.|:..|||.
pombe   133 ---------------PQVQRLP--------ASAPKHDLYSSANASSASLHPTEQRTTSSPTIPSY 174

  Fly  1086 VIMKHHIRVEPREPPKRAHSVEIEEVVSKPKARNICTNNHEVIDVLSQRLANINKIASGNTQANL 1150
            .              .|.|:       ..|.:             ||.||.|:....:.||
pombe   175 A--------------NRTHT-------DSPTS-------------LSHRLPNVPDTNALNT---- 201

  Fly  1151 SKQLQKNYAGEQAKELGERSPSENASNSDSESEEESSDDEEDTPKLGARPAPLQSI--KSVTNVQ 1213
               :|.|.:...:...|.::..:::||..|..|...|...:....|.:..:.::::  ||:::..
pombe   202 ---VQANNSSTSSLSQGAQTGIDSSSNYLSRIEMLESSLAKSNSLLDSSKSEMEALKAKSISDAT 263

  Fly  1214 VYKGK--TLEQHLDSESSDDEDDVTTADEMYDEEEQIEE-------------------EQEGLV- 1256
            .:|.:  .||:.|...|.:.|..:   .::.|.|.:|:|                   .||.:|
pombe   264 KHKNEIFQLEEKLHEASHEAEISI---KKLNDAENRIKELENNPTLSFNPELEKNLKLMQELIVA 325

  Fly  1257 EEMEDDYIVEEDLSVIYEEESELERSSEY---AKTVIRKDDSR----STI-VDDIEKQIEENDDD 1313
            |..:..:|||.: |.|...::|.||..:.   ||:....:|.|    :|: :..|.:.|..|...
pombe   326 ESSKTQHIVELE-SCIDSLKAETERWKKVAINAKSAKIDEDIRLFTMTTVPMKSIRELISPNGFL 389

  Fly  1314 DDDEESNSVTVRLPLRF---------SFSRSSNDENIATVQ------------VGNTTQIEEKPI 1357
            |:         :|.:|:         |..|.|..:.::|.:            :...:.:||.|.
pombe   390 DE---------QLYIRYFVEMNVFVASLRRDSPSQWMSTAKDIALTLEAIVSSLREKSLLEELPD 445

  Fly  1358 IAS------SFSVAKVES--------------DDEDDDCEVSV-------TISLSNSSRSN-SVE 1394
            :..      ||:.:.:|.              ..:...|.:|:       |..|:|:.:|: ||.
pombe   446 LGKKVDDLCSFTNSLMEQVRLAVINGALLPIYHVDASACSISISLMDIAKTYGLTNTGKSSLSVG 510

  Fly  1395 KVAQPYRPSNAYPVEDIS--TPIKTSEEDVSASFSLGMRNKFMGETIANDVTNNISRDQAKPKND 1457
            :       ::.:||:|:.  :..||...:.|..||  ..|:.:.:.|::|  ::.|..|.:...|
pombe   511 R-------NSLHPVDDLKALSVAKTLLSEKSKQFS--ETNQKLLDAISSD--SSSSTIQQRVHED 564

  Fly  1458 VTEVE------SSPKEEFDFFA-------TLMATKMQAQKMMEQ---SKNFWKTPDPKIVEPAAE 1506
            :..:.      |||.|.....|       .|...:....:::||   .:||..| |...|.|..:
pombe   565 INVIRDTLFDVSSPLELMRDRAAYAVIHNALQEMRRYCMQLIEQEGHGENFGFT-DNNSVPPLTD 628

  Fly  1507  1506
            pombe   629  628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG44085	NP_001260440.1	None
spa2	NP_594077.1	GIT_SHD	34..61	CDD:462506	3/27 (11%)
		GIT	82..112	CDD:128828	8/29 (28%)
		Mplasa_alph_rch	<196..>354	CDD:275316	35/168 (21%)