Protein Alignment Sirt1 and SRT1

DIOPT Version :10

• Sequence 1: NP_477351.1
• Gene: Sirt1 / 34708
• FlyBaseID: FBgn0024291
• Length: 823
• Species: Drosophila melanogaster
• Sequence 2: NP_200387.1
• Gene: SRT1 / 835670
• AraportID: AT5G55760
• Length: 473
• Species: Arabidopsis thaliana
• Alignment Length: 296
• Identity: 77/296 - (26%)
• Similarity: 132/296 - (44%)
• Gaps: 53/296 - (17%)

  Fly   212 DDVISLVKKSQKIIVLTGAGVSVSCGIPDFRSTNGIYARLAHDFPDLPDPQAMFDINYFKRDPRP 276
            :::..|::||:.::|.||||:|.||||||||...||:. |..:..|||            :...|
plant    35 EELAKLIQKSKHLVVFTGAGISTSCGIPDFRGPKGIWT-LQREGKDLP------------KASLP 86

  Fly   277 FYKFAREIYPGEFQPSPCHRFIKMLETKGKLLRNYTQNIDTLERVAGI--QRVIECHGSFSTASC 339
            |::         ..||..|..:..||..|.|....:||:|.|...:||  :::.|.||......|
plant    87 FHR---------AMPSMTHMALVELERAGILKFVISQNVDGLHLRSGIPREKLSELHGDSFMEMC 142

  Fly   340 TKCRFKCNADALRADIFAQRIPVCPQCQPNKEQSVDASVAVTEEELRQLV---ENGIMKPDIVFF 401
            .    .|.|:.|| |...:.|.:       ||.|...||.....:|:..|   |:.:...:|.
plant   143 P----SCGAEYLR-DFEVETIGL-------KETSRKCSVEKCGAKLKDTVLDWEDALPPKEID-- 193

  Fly   402 GEGLPDEYHTVMATDKDVCDLLIVIGSSLKVRPVAHIP-SSIPATVPQILINREQL-HHLKFDVE 464
                |.|.|...|      ||::.:|:||::.|..::| ..:......:::|.::. ...|.:|.
plant   194 ----PAEKHCKKA------DLVLCLGTSLQITPACNLPLKCLKGGGKIVIVNLQKTPKDKKANVV 248

  Fly   465 LLGDSDVIINQICHRLSDNDDCWRQLCCDESVLTES 500
            :.|..|.::..:...|:.....:.::...:.:||:|
plant   249 IHGLVDKVVAGVMESLNMKIPPYVRIDLFQIILTQS 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt1	NP_477351.1	SIRT1	222..476	CDD:238699	70/260 (27%)
SRT1	NP_200387.1	SIRT7	45..252	CDD:238701	68/252 (27%)