Protein Alignment DnaJ-H and DNAJA1

DIOPT Version :10

• Sequence 1: NP_001260431.1
• Gene: DnaJ-H / 34707
• FlyBaseID: FBgn0032474
• Length: 440
• Species: Drosophila melanogaster
• Sequence 2: NP_001530.1
• Gene: DNAJA1 / 3301
• HGNCID: 5229
• Length: 397
• Species: Homo sapiens
• Alignment Length: 399
• Identity: 148/399 - (37%)
• Similarity: 227/399 - (56%)
• Gaps: 25/399 - (6%)

  Fly     7 YDVLKVAPDATDEEIKKNYRKLAKEFHPDKNPDAGDKFKEISFAYEVLSDPEKRRIYDRYGLKGL 71
            ||||.|.|:||.||:||.|||||.::||||||:.|:|||:||.|||||||.:||.:||:.|.:.:
Human     8 YDVLGVKPNATQEELKKAYRKLALKYHPDKNPNEGEKFKQISQAYEVLSDAKKRELYDKGGEQAI 72

  Fly    72 QEGAE--GFSDASEFFAQWFPFDRVSSEGRGR----RNGK-VVVKVELTLEEIYVGGMKKKVEYN 129
            :||..  ||....:.|..:|       .|.||    |.|| ||.::.:|||::| .|..:|:...
Human    73 KEGGAGGGFGSPMDIFDMFF-------GGGGRMQRERRGKNVVHQLSVTLEDLY-NGATRKLALQ 129

  Fly   130 RQKLCSKCNGDGGPKEAHESCETCGGAGRAAAFTFMG---LSPFDTTCPTCDGRGFTIRDDKKCS 191
            :..:|.||.|.||.|.|.|.|..|.|.|.......:|   :....:.|..|.|.|..|....:|.
Human   130 KNVICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQIGPGMVQQIQSVCMECQGHGERISPKDRCK 194

  Fly   192 PCQGSGFVEQKMKRDLVVERGAPHMLKVPFANEGHQMRGGEFGDLIVVISQMEHPIFQRRHANLY 256
            .|.|...|.:|...::.:::|.....|:.|..||.|..|.|.||:|:|:.|.:|.:|.||..:|:
Human   195 SCNGRKIVREKKILEVHIDKGMKDGQKITFHGEGDQEPGLEPGDIIIVLDQKDHAVFTRRGEDLF 259

  Fly   257 MRDLEINITEALCGYSHCFKHLDGRNVCLRTYPGEVLQHNQIKMVRGSGMPVFNKATDSGDLYMK 321
            | .::|.:.|||||:......||.|.:.:.::||::::|..||.|...|||::.:..:.|.|.::
Human   260 M-CMDIQLVEALCGFQKPISTLDNRTIVITSHPGQIVKHGDIKCVLNEGMPIYRRPYEKGRLIIE 323

  Fly   322 FKVKFPDNDFATAPQLAMLEDLLPPRQPIVIPKNAEEVQMTDYKPQPRQQEDEDGQSSHFE---- 382
            |||.||:|.|.:..:|::||.|||.|:.:......::|::.|:.|...::...:|::...:
Human   324 FKVNFPENGFLSPDKLSLLEKLLPERKEVEETDEMDQVELVDFDPNQERRRHYNGEAYEDDEHHP 388

  Fly   383 --GVQCQTA 389
              ||||||:
Human   389 RGGVQCQTS 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DnaJ-H	NP_001260431.1	PTZ00037	1..386	CDD:240236	144/394 (37%)
DNAJA1	NP_001530.1	PTZ00037	2..394	CDD:240236	144/394 (37%)
		CXXCXGXG motif	134..141		4/6 (67%)
		CXXCXGXG motif	150..157		3/6 (50%)
		CXXCXGXG motif	177..184		3/6 (50%)
		CXXCXGXG motif	193..200		3/6 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	352..397		9/44 (20%)