Protein Alignment kmg and ZNF513

DIOPT Version :10

• Sequence 1: NP_609604.1
• Gene: kmg / 34706
• FlyBaseID: FBgn0032473
• Length: 747
• Species: Drosophila melanogaster
• Sequence 2: NP_653232.3
• Gene: ZNF513 / 130557
• HGNCID: 26498
• Length: 541
• Species: Homo sapiens
• Alignment Length: 467
• Identity: 96/467 - (20%)
• Similarity: 150/467 - (32%)
• Gaps: 146/467 - (31%)

  Fly   295 NSSSDSEETAKSP----------------------------SPDTRELVSGKEQFQCQKCSYSTP 331
            ::.|:.||.|:.|                            .|....|:..:..:.|:.|::.:.
Human    96 SAESEVEEPARGPGEARGERPGPACQLCGGPTGEGPCCGAGGPGGGPLLPPRLLYSCRLCTFVSH 160

  Fly   332 IRARFKKHVKYHS--MPLIKCSSCDFHTPYKWNLDRHTKNHGANGHFKCSCCDFSTDIKQSLTIH 394
            ..:..|:|::.||  .| .:|..|.:.:....||.|||:.|.....::|..|.|:.....:|..|
Human   161 YSSHLKRHMQTHSGEKP-FRCGRCPYASAQLVNLTRHTRTHTGEKPYRCPHCPFACSSLGNLRRH 224

  Fly   395 ESNHHVP--MPVHQMGNR------SRDEAEDLVDQQSSGSRKPET----------FKNGGAT--- 438
            :..|..|  .|....|.|      :|..:.  .:|:.:..|:||.          ...|||:
Human   225 QRTHAGPPTPPCPTCGFRCCTPRPARPPSP--TEQEGAVPRRPEDALLLPDLSLHVPPGGASFLP 287

  Fly   439 -----------VAST------ESLLPRTSGIVCSHCQK--------RVGNAMQLINHLQVCTLAL 478
                       :..|      |.|.|.|    |..|.:        |:|.||        |...:
Human   288 DCGQLRGEGEGLCGTGSEPLPELLFPWT----CRGCGQELEEGEGSRLGAAM--------CGRCM 340

  Fly   479 HNTTQLQASINAEVDLHDEDFPNAPTD----LSYCGVETAPGYGEVTEVLPEEPEDLA------P 533
            .......||          ..|..|:|    .|.|...|            ..|..||      .
Human   341 RGEAGGGAS----------GGPQGPSDKGFACSLCPFAT------------HYPNHLARHMKTHS 383

  Fly   534 LKKVFKCPHCSFWAATASRFHVHIVGHLNRKPFECSLCAYRSNWRWDITKHIRLK--------AL 590
            .:|.|:|..|.:.:|.......|...|...||::|.||.|......::.:|.|:.        :|
Human   384 GEKPFRCARCPYASAHLDNLKRHQRVHTGEKPYKCPLCPYACGNLANLKRHGRIHSGDKPFRCSL 448

  Fly   591 RDRSHNQAQVL---MNDETGRRNY---------AKYNQYLTMMKVSAEQLADSKGMRTGEMIV-- 641
            .:.|.||:..|   |...||.:.:         ..::.|....||.....|...|:...|...
Human   449 CNYSCNQSMNLKRHMLRHTGEKPFRCATCAYTTGHWDNYKRHQKVHGHGGAGGPGLSASEGWAPP 513

  Fly   642 -MPPEKLDDHHP 652
             .||..|....|
Human   514 HSPPSVLSSRGP 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kmg	NP_609604.1	C2H2 Zn finger	540..560	CDD:275370	4/19 (21%)
		C2H2 Zn finger	568..586	CDD:275370	5/17 (29%)
ZNF513	NP_653232.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..118		5/21 (24%)
		C2H2 Zn finger	152..172	CDD:275368	4/19 (21%)
		zf-H2C2_2	164..189	CDD:463886	7/25 (28%)
		C2H2 Zn finger	180..200	CDD:275368	7/19 (37%)
		zf-H2C2_2	192..217	CDD:463886	9/24 (38%)
		C2H2 Zn finger	208..228	CDD:275368	5/19 (26%)
		C2H2 Zn finger	362..382	CDD:275368	6/31 (19%)
		zf-H2C2_2	374..399	CDD:463886	6/24 (25%)
		C2H2 Zn finger	390..410	CDD:275368	4/19 (21%)
		zf-H2C2_2	402..425	CDD:463886	8/22 (36%)
		COG5048	414..>487	CDD:227381	16/72 (22%)
		C2H2 Zn finger	418..438	CDD:275368	6/19 (32%)
		C2H2 Zn finger	446..466	CDD:275368	6/19 (32%)
		C2H2 Zn finger	474..493	CDD:275368	1/18 (6%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	492..541		9/34 (26%)