Protein Alignment kmg and znf335

DIOPT Version :10

• Sequence 1: NP_609604.1
• Gene: kmg / 34706
• FlyBaseID: FBgn0032473
• Length: 747
• Species: Drosophila melanogaster
• Sequence 2: XP_004918689.2
• Gene: znf335 / 100498615
• XenbaseID: XB-GENE-981913
• Length: 1427
• Species: Xenopus tropicalis
• Alignment Length: 766
• Identity: 144/766 - (18%)
• Similarity: 235/766 - (30%)
• Gaps: 285/766 - (37%)

  Fly   104 NDDELPQCKIRRNYSCNQCAFFTQNPRSHLSHLRDVHGERIVINECKLCLYASRHFQKLVRHMKM 168
            ||   ||.     :.|.||::..:...|...|:.:..|.:..  :|:.|.|.|.:.:.:||| ..
 Frog   693 ND---PQA-----FQCQQCSYQCRRWSSLKEHMYNHKGSKPY--KCEECEYTSVYKKDVVRH-SA 746

  Fly   169 VHGCSDDGGAVQGSGAQPRGKRNLSREVRKRRLEESIEGQGATGQCLDLSVLRMIQNGPPLEQLK 233
            ||                       ||.||::.|::  .:.|:..|            |...::
 Frog   747 VH-----------------------REDRKKKSEKT--SKPASYPC------------PVCGRI- 773

  Fly   234 VELQQQEMQLLASVQAYNRQQEMLQLQQI--------VESHDNIFSMAYEFQTKLMPPKQAESLK 290
                            |..|:.:.|..:|        .:.....|...|.|:..|:...|.
 Frog   774 ----------------YTMQKRLTQHMKIHSAEKPHMCDKCGKAFKKRYTFKMHLLTHLQC---- 818

  Fly   291 LEQQNSSSDSEETAKSPSPDTRELVSGKEQFQCQKCSYSTPIRARFKKHVKYH--SMPLIKCSSC 353
                                     .||.:::|:.|.|....|.:...|...|  ..| .|||.|
 Frog   819 -------------------------VGKSRYKCEFCEYICGDRKQLLNHQLTHMNDKP-FKCSQC 857

  Fly   354 DFHTPYKWN--LDRHTKNHGANGHFKCSCCDFSTDIKQSLTIHESNHHVPMPVHQMGNR------ 410
            .:|| |:.:  |......|.....|.|..|.|:|..|::|.:|..:.| |:..::...|
 Frog   858 KYHT-YRQDFLLSHMATKHAGGKPFACDHCHFTTKHKKNLRLHVQSRH-PLLYNEWSQRHPEETP 920

  Fly   411 -------SRDEAEDL------------------------------------VDQQSSG------- 425
                   |..:.|:|                                    .::||.|
 Frog   921 SRRRPFFSMQQIEELKQLHEQSENQGPSPQEVVMDAAELSYQILQPTSQSPTEEQSHGALGAAAI 985

  Fly   426 ------------------------SRKPET--------FKNG-GATVASTESLL--PRTSGIVCS 455
                                    :|:..|        .|:| |..|.|::|:.  |..:.::..
 Frog   986 IYEQEGEEEEYATRAALDLLLNMSTRREGTGGPLQVAVVKSGSGGEVQSSQSMAHEPHMAQVLTL 1050

  Fly   456 HCQKRVGN----------------------AMQLI---NHLQVCTLALHNTTQLQASINAEVDL- 494
            |.:   ||                      |:|.|   |.......:|.||..:.||:.:|...
 Frog  1051 HVE---GNGVTSVQEAGYEDAGVEDTGYEGAVQQITIDNAFTTAEYSLINTENIPASLCSETSAS 1112

  Fly   495 ----------------------HDEDFPNAPTDLSY----CGVETAPGYGEVTEVLPEEPEDLAP 533
                                  |..|...||....:    ||          |..|.....::..
 Frog  1113 PGSTLLGENIKDKILRKSQQAEHVSDHSAAPAAKKFCCKLCG----------TTFLGRSEMEIHK 1167

  Fly   534 LKKV----FKCPHCSFWAATASRFHVHIVGHLNRKPFECSLCAYRSNWRWDITKHIRLKALRDRS 594
            ...|    ||||.|.|.||.......|:..|.:|:|..|..|::....:.|:::|..:.. ..|.
 Frog  1168 RAHVPSGGFKCPDCIFTAANWPEVRNHLSVHSDRRPHRCDQCSFACKNKRDLSRHSMIHT-NQRP 1231

  Fly   595 HNQAQVLMNDETGRRNYAKYN-QYLTMMKVSAEQLADSKGMRTGEMIVMPPEKLDDHHPMETEEI 658
            |:..  :......|:.:.|:: |.|...|.:..|        ..|..:.|...|::.|...|:|
 Frog  1232 HSCP--ICGQRFTRKAHLKFHIQRLHRGKNNEPQ--------ENEAELTPAPSLEEEHIFLTQE- 1285

  Fly   659 IEMVDSAHSTSALDLRKPRDDQTEDLAGNSDELPQEGAKTE--PNLEPLSF 707
             |.:.|...|:.:......|.||......:|...|.....|  |:|.|..:
 Frog  1286 -ESMASQEDTAYIQEITTADGQTLQQLVTADNQVQYIISQEDIPHLIPQEY 1335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kmg	NP_609604.1	C2H2 Zn finger	540..560	CDD:275370	7/19 (37%)
		C2H2 Zn finger	568..586	CDD:275370	4/17 (24%)
znf335	XP_004918689.2	C2H2 Zn finger	670..690	CDD:275368
		C2H2 Zn finger	700..720	CDD:275368	5/19 (26%)
		zf-H2C2_2	712..737	CDD:463886	7/26 (27%)
		C2H2 Zn finger	728..748	CDD:275368	7/20 (35%)
		C2H2 Zn finger	767..787	CDD:275368	5/48 (10%)
		zf-H2C2_2	779..804	CDD:463886	3/24 (13%)
		C2H2 Zn finger	795..815	CDD:275368	4/19 (21%)
		C2H2 Zn finger	826..846	CDD:275368	5/19 (26%)
		C2H2 Zn finger	854..875	CDD:275368	7/21 (33%)
		C2H2 Zn finger	883..904	CDD:275368	7/20 (35%)
		C2H2 Zn finger	1178..1198	CDD:275368	7/19 (37%)
		C2H2 Zn finger	1206..1226	CDD:275368	4/19 (21%)
		C2H2 Zn finger	1234..1255	CDD:275368	3/22 (14%)