DRSC/TRiP Functional Genomics Resources

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Protein Alignment: Pk34A and GSK3B

Sequence 1:NP_609603.1 Gene:Pk34A FlyBaseID:FBgn0028410 Length:392 Species:Drosophila melanogaster
Sequence 2:NP_002084.2 Gene:GSK3B HGNCID:4617 Length:433 Species:Homo sapiens

Alignment Length:367 Identity:141/368 (38%)
Similarity:201/368 (55%) Gaps:27/368 (7%)


  Fly    25 SVISTYAVGRLCSEPALVRIEVKDLIGSGSFGRVYQAHVNESEEIVAVKQTLYNPKLSQGEAEIM 89
            :|::|...|.  ..|..|......:||:||||.||||.:.:|.|:||:|:.|.:.:....|.:||
Human    39 TVVATPGQGP--DRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIM 101

  Fly    90 GQLKDHNNIVRL--IMHSSVSLGFPSVD-YVLLVMEYMPMTLLDYINYHLTVLQPAERLINVRIL 151
            .:| ||.|||||  ..:||   |....: |:.||::|:|.|:.....::....|... :|.|::.
Human   102 RKL-DHCNIVRLRYFFYSS---GEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLP-VIYVKLY 161

  Fly   152 SYQMFRGLGYLHLLGISHRDVKPENLLIDNQKMVLKLSDFGSAKLLVPQEPSISYICSRLYRAPE 216
            .||:||.|.|:|..||.|||:||:|||:|....||||.||||||.||..||::||||||.|||||
Human   162 MYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPE 226

  Fly   217 LFAGYELYSCAVDIWSAGCVLAELLKGYPLFSSHKHDRKQLRLIVNMLGTDGLERAPEILSKCGN 281
            |..|...|:.::|:|||||||||||.|.|:|.... ...||..|:.:|||...|:..|:......
Human   227 LIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDS-GVDQLVEIIKVLGTPTREQIREMNPNYTE 290

  Fly   282 SLHPRTTRPSWN-------------YLLNTAVPQDLCGLLNSCFIYEAAARISPMMACSHGSYDE 333
            ...|:.....|.             .:.....|.:...|.:....|...||::|:.||:|..:||
Human   291 FKFPQIKAHPWTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDE 355

  Fly   334 LRIMDAMALPMPNGNPLPPLFDFNSLEMGTDPKLWVNLLPIH 375
            ||..:   :.:|||...|.||:|.:.|:.::|.|...|:|.|
Human   356 LRDPN---VKLPNGRDTPALFNFTTQELSSNPPLATILIPPH 394

Known Domains:


GeneSequenceDomainRegion External IDIdentity
Pk34ANP_609603.1 STKc_GSK3 39..334 CDD:271039 123/311 (40%)
S_TKc 45..328 CDD:214567 118/299 (39%)
GSK3BNP_002084.2 STKc_GSK3 51..356 CDD:271039 123/311 (40%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 1 0.900 E2759_KOG0658
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 D990896at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 1 0.960
User_Submission 00.000 Not matched by this tool.
32.870

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