Protein Alignment PICK1 and Y57G11C.22

DIOPT Version :10

• Sequence 1: NP_001285881.1
• Gene: PICK1 / 34677
• FlyBaseID: FBgn0032447
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_001041046.1
• Gene: Y57G11C.22 / 178409
• WormBaseID: WBGene00013317
• Length: 444
• Species: Caenorhabditis elegans
• Alignment Length: 462
• Identity: 183/462 - (39%)
• Similarity: 282/462 - (61%)
• Gaps: 49/462 - (10%)

  Fly    85 ELDRLGMTVSTNAVVITKDQSNLIGISIGGGAPMCPCLYIVQIFDGTPAAREGSLQSGDELLAVN 149
            |.|||||.:.:..:.:|||:..::|||||||.|.|||:|:||:||.:||.::|.::.|||::|:|
 Worm     6 EEDRLGMRIQSETIELTKDEKGVVGISIGGGGPYCPCVYVVQVFDKSPAFKDGRIRCGDEIVAIN 70

  Fly   150 SVSVKGKTKVEVAKMIQTATDEVVIHYNKLHADPEQGKTLDIILKKLKHRIVDNLSSNTADTLGL 214
            .::|||:.|..||::||.:.:.|.|..|||.....:||||||::||:||::|:.:..::||.|||
 Worm    71 GITVKGERKSAVAQLIQVSLNPVKITINKLEEANTKGKTLDILIKKVKHKVVEFVDQDSADALGL 135

  Fly   215 SRAILCNDSLVKRLEELEGTELMYKGLVEHARRMLKAYYDLLQTYKSFGDCFTQISVHEPQQRAS 279
            |||||.||.|.::.:.||.....|:.||.:...|.:....:.:..|.||..|..::.||.||.|:
 Worm   136 SRAILTNDPLAEKEKILEENAEFYRHLVAYFGDMFQYQQKISECQKEFGSIFCDLAAHEKQQTAN 200

  Fly   280 EAFRTFGEFHRTLEKDGLGIIKQIKPVLADLGTYLNKAIPDTKLTVRRYADAKFTYLSYCLKVKE 344
            |||.:||:.||.:.|........::.:::||..|::..:|||:||:::|.|.|:.|||||||:||
 Worm   201 EAFSSFGDKHRMIAKKQSESAVPLQKMVSDLQVYIDHVVPDTRLTIKKYLDVKYEYLSYCLKLKE 265

  Fly   345 MDDEEHGFAALQEPLYRVETGNYEYRLILRCRQDARSKFAKLRTDVLEKMELLECKHAMDLNKQL 409
            |||||..|.|:|||||||||||||||::|||||:.|::|.|:|.||:.|:|||:.||..|:.:.|
 Worm   266 MDDEEVEFVAIQEPLYRVETGNYEYRVMLRCRQECRARFMKMRDDVMVKIELLDQKHVRDIAQHL 330

  Fly   410 RSLLESLAELHRS----LVDRLDSLPPLFPIEVDFKETDFQYKSSTLK---PQELDDDEIEANNH 467
            ....:::|:..:.    |.:|:|     .|||:|.::.:....:|..|   .:|:..|.|..|::
 Worm   331 AIFAKTMAKCQQECAEILKERID-----VPIEIDLEQLNLNMNTSDGKANGEEEMGQDAIVLNDN 390

  Fly   468 PHSTPSQVDCGFEAVEQPAAIINVEAAKASVDSST--------LQSASENETL----------LK 514
            |             :|.....:|      .:.|||        |:..|:|:|.          |:
 Worm   391 P-------------LEGDLIDVN------DIGSSTEFNEPRISLRRDSQNDTSQPLLGAPDSPLE 436

  Fly   515 ELGLYDV 521
            ||.|.|:
 Worm   437 ELSLIDI 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PICK1	NP_001285881.1	PDZ_PICK1-like	96..179	CDD:467205	38/82 (46%)
		BAR_PICK1	221..436	CDD:153343	91/218 (42%)
Y57G11C.22	NP_001041046.1	PDZ_PICK1-like	17..100	CDD:467205	38/82 (46%)
		BAR_PICK1	142..356	CDD:153343	91/218 (42%)