Protein Alignment PICK1 and PICK1

DIOPT Version :10

• Sequence 1: NP_001285881.1
• Gene: PICK1 / 34677
• FlyBaseID: FBgn0032447
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: XP_061518153.1
• Gene: PICK1 / 1278125
• VectorBaseID: AGAMI1_000038
• Length: 602
• Species: Anopheles gambiae
• Alignment Length: 555
• Identity: 326/555 - (58%)
• Similarity: 393/555 - (70%)
• Gaps: 92/555 - (16%)

  Fly     6 EDDFFFEEDKMPEPLLIQLDGDGAQAVRQPKERTEQREHASGSVAPNEATVMLCSPAGFSCDSAS 70
            :|..|...|.:|:|:|                      :|.|.|..|: .:|||
Mosquito    99 DDIAFVSNDDLPDPVL----------------------YADGCVDDNK-IIMLC----------- 129

  Fly    71 GDRFGIESASRQKYELDRLGMTVSTNAVVITKDQSNLIGISIGGGAPMCPCLYIVQIFDGTPAAR 135
                       |:.|::|||||||:..|||.||.|||||||||||||:||||||||:||||||||
Mosquito   130 -----------QRQEMERLGMTVSSGTVVIKKDTSNLIGISIGGGAPLCPCLYIVQVFDGTPAAR 183

  Fly   136 EGSLQSGDELLAVNSVSVKGKTKVEVAKMIQTATDEVVIHYNKLHADPEQGKTLDIILKKLKHRI 200
            ||:||||||||.||.||||||||||||||||:||:||:||||||||||.||:||||:|||:|||:
Mosquito   184 EGTLQSGDELLGVNGVSVKGKTKVEVAKMIQSATEEVMIHYNKLHADPTQGETLDIVLKKMKHRL 248

  Fly   201 VDNLSSNTADTLGLSRAILCNDSLVKRLEELEGTELMYKGLVEHARRMLKAYYDLLQTYKSFGDC 265
            |:.:||:|||||||||||||||||||||:|||.||.||||||:||||||||::|:||||::||:.
Mosquito   249 VERMSSSTADTLGLSRAILCNDSLVKRLQELERTETMYKGLVDHARRMLKAHFDVLQTYQAFGNI 313

  Fly   266 FTQISVHEPQQRASEAFRTFGEFHRTLEKDGLGIIKQIKPVLADLGTYLNKAIPDTKLTVRRYAD 330
            |..|||.|||.|||||||.|||.||.:||||:.:||.:||:|||:||||:||||||||||:||||
Mosquito   314 FASISVREPQPRASEAFRIFGELHRNMEKDGIKMIKTLKPILADMGTYLHKAIPDTKLTVKRYAD 378

  Fly   331 AKFTYLSYCLKVKEMDDEEHGFAALQEPLYRVETGNYEYRLILRCRQDARSKFAKLRTDVLEKME 395
            |||:|||||||:|||||||||:||:||||||||||||||||||||||:||.||||||:|||||:|
Mosquito   379 AKFSYLSYCLKIKEMDDEEHGYAAIQEPLYRVETGNYEYRLILRCRQEARLKFAKLRSDVLEKIE 443

  Fly   396 LLECKHAMDLNKQLRSLLESLAELHRSLVDRLDSLPPLFPIEVDFKETDFQYKSS-TLKPQELDD 459
            |||||||.||..|||..:|.||.|....|:||:|:|.|||||||.|.:.|||||: ..:.:|..|
Mosquito   444 LLECKHARDLASQLRKFIEGLATLASETVERLESIPNLFPIEVDLKASAFQYKSAIKFQAEEYTD 508

  Fly   460 DEIEANNHPHSTPSQVDCGFEAVEQPAAIINVEAAKAS--------------------------V 498
            :||     |.:.        ||:||      ||.||::                          :
Mosquito   509 EEI-----PQAE--------EAIEQ------VETAKSAQAKTTGDLEQSNGTDVSGQLLGGFEEI 554

  Fly   499 DSSTLQSASENE-TLLKELGLYDVDLLSNPQTISN 532
            |.:...||..:| .||.||||..:||..:.:.||:
Mosquito   555 DLNKGTSAGPSEHDLLNELGLAGIDLSVSSKPISH 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PICK1	NP_001285881.1	PDZ_PICK1-like	96..179	CDD:467205	70/82 (85%)
		BAR_PICK1	221..436	CDD:153343	162/214 (76%)
PICK1	XP_061518153.1	None