Protein Alignment nub and POU4F3

DIOPT Version :10

• Sequence 1: NP_001097153.1
• Gene: nub / 34669
• FlyBaseID: FBgn0085424
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: NP_002691.1
• Gene: POU4F3 / 5459
• HGNCID: 9220
• Length: 338
• Species: Homo sapiens
• Alignment Length: 373
• Identity: 122/373 - (32%)
• Similarity: 175/373 - (46%)
• Gaps: 72/373 - (19%)

  Fly   601 SPQDFAQFHQLLQQRQVALTQQFNSYMELLRSGSLGLAQ---DDPALTAQVAAAQFLMQSQLQAL 662
            |.|.|. .|.:||:      .:|:|    |.|||..:.:   ..|.|...:..:   ....|.|.
Human     6 SKQPFG-MHPVLQE------PKFSS----LHSGSEAMRRVCLPAPQLQGNIFGS---FDESLLAR 56

  Fly   663 SQASQQLQALQKQQQRQVDEPLQLNHKMTQQPRSSTPHSIRSPIAIRSPASSPQQLHHHHHHPL- 726
            ::|...:..:...:.... :|....|.|:..|.:||..::        |.|.|..|..|.||.:
Human    57 AEALAAVDIVSHGKNHPF-KPDATYHTMSSVPCTSTSSTV--------PISHPAALTSHPHHAVH 112

  Fly   727 ---------QITPPSSAASLKLSGMLTPSTPTSGTQ-----------MSQGTTTPQPKTVASAAA 771
                     .|:|     :|.:||:..|.......|           :.|......|.|||..:|
Human   113 QGLEGDLLEHISP-----TLSVSGLGAPEHSVMPAQIHPHHLGAMGHLHQAMGMSHPHTVAPHSA 172

  Fly   772 ARAAGEPSPEETTDLEELEQFAKTFKQRRIKLGFTQGDVGLAMG--KLYG-NDFSQTTISRFEAL 833
            ..|.   ..:..:|..|||.||:.|||||||||.||.|||.|:.  |:.| ...||:||.|||:|
Human   173 MPAC---LSDVESDPRELEAFAERFKQRRIKLGVTQADVGAALANLKIPGVGSLSQSTICRFESL 234

  Fly   834 NLSFKNMCKLKPLLQKWLDDADRTIQATGGVFDPAALQATVSTPEII--GRRRKKRTSIETTIRG 896
            .||..||..|||:||.||::|:            ||.:...|.||:.  ..|::|||||....:.
Human   235 TLSHNNMIALKPVLQAWLEEAE------------AAYREKNSKPELFNGSERKRKRTSIAAPEKR 287

  Fly   897 ALEKAFLANQKPTSEEITQLADRLSMEKEVVRVWFCNRRQKEKRINPS 944
            :||..|....:|:||:|..:|::|.::|.||||||||:|||:||:..|
Human   288 SLEAYFAIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKYS 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nub	NP_001097153.1	POU	791..855	CDD:197673	38/66 (58%)
		Homeodomain	884..940	CDD:459649	26/55 (47%)
POU4F3	NP_002691.1	POU-IV box	56..65		1/8 (13%)
		POU	179..256	CDD:197673	42/76 (55%)
		Homeodomain	275..331	CDD:459649	26/55 (47%)