Protein Alignment nub and pou5f3.3

DIOPT Version :10

• Sequence 1: NP_001097153.1
• Gene: nub / 34669
• FlyBaseID: FBgn0085424
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: NP_001123836.1
• Gene: pou5f3.3 / 100170593
• XenbaseID: XB-GENE-5903504
• Length: 423
• Species: Xenopus tropicalis
• Alignment Length: 407
• Identity: 139/407 - (34%)
• Similarity: 195/407 - (47%)
• Gaps: 90/407 - (22%)

  Fly   570 PLL----ALPGMS-SPQAQLAAAGLGM--NNPLLTGSLS----PQDFAQFHQLLQQRQVALTQQF 623
            |:|    |.|..| ||       |||.  .|....|:.:    ||.|  ||.     ..|:..::
 Frog     4 PVLYNQPAFPNFSYSP-------GLGQEGGNYQYLGNYNAPSYPQPF--FHV-----PPAIKSEY 54

  Fly   624 NSYMELLRSGSLGLAQDDPALTAQVAAAQFLMQSQLQALSQASQQLQALQKQQQRQVDEPLQLNH 688
            .:..| :..||...|..|..|     ...|...:|:.|||......:...::           :|
 Frog    55 GAQDE-VTGGSCHAAPFDWHL-----YPHFQFSNQVGALSSGDPSPEGRNEE-----------DH 102

  Fly   689 KMTQQPRSSTPHSIRSPIAIRSPASSPQQLHHHHHHPLQITPPSSAASLKLSGMLTPSTPTSGTQ 753
            ....:.|||...|..||:.       |....:.||.|.|..|...|.     |:.:.:.|..|.:
 Frog   103 GSISEERSSGTPSPNSPMV-------PSYAQYWHHAPWQGNPTGQAL-----GLPSRAHPDGGEK 155

  Fly   754 MSQ-----------GTTTPQPKTVASAAAARAAG---EPSP----------EETTDLEELEQFAK 794
            ..|           |.:..:.:.|:||.::||..   .|||          |:.|.|||:|:|||
 Frog   156 PQQSDCSPTASLESGASNTEDEEVSSALSSRAERGLCSPSPNNASFGSGNEEDGTTLEEMEEFAK 220

  Fly   795 TFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLQKWLDDADRTIQ 859
            ..||:|:.||:||||:|.|:|.|||..||||||.|||:|.|:|||||||||||::||.:|:....
 Frog   221 ELKQKRVALGYTQGDIGHALGILYGKMFSQTTICRFESLQLTFKNMCKLKPLLEQWLGEAENNDN 285

  Fly   860 ATGGVFDPAALQATVSTPEI--IGRRRKKRTSIETTIRGALEKAFLANQKPTSEEITQLADRLSM 922
                      ||..:...::  ..|:||.||..::.::|.||..|:.||||.:.|:.::|..|.:
 Frog   286 ----------LQEMIHKAQLEEQNRKRKMRTCFDSVLKGRLEGHFMCNQKPGARELAEIAKELGL 340

  Fly   923 EKEVVRVWFCNRRQKEK 939
            ||:||||||||||||||
 Frog   341 EKDVVRVWFCNRRQKEK 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nub	NP_001097153.1	POU	791..855	CDD:197673	42/63 (67%)
		Homeodomain	884..940	CDD:459649	31/56 (55%)
pou5f3.3	NP_001123836.1	PTZ00395	<7..>177	CDD:185594	46/212 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	85..211		31/148 (21%)
		Pou	210..281	CDD:459692	47/70 (67%)
		Homeodomain	302..357	CDD:459649	29/54 (54%)