Protein Alignment nub and pou6f2

DIOPT Version :10

• Sequence 1: NP_001097153.1
• Gene: nub / 34669
• FlyBaseID: FBgn0085424
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: XP_021325963.1
• Gene: pou6f2 / 100001518
• ZFINID: ZDB-GENE-091118-71
• Length: 719
• Species: Danio rerio
• Alignment Length: 825
• Identity: 193/825 - (23%)
• Similarity: 279/825 - (33%)
• Gaps: 298/825 - (36%)

  Fly   292 PPLPLLAD------QDDGTRRMRDKKLTLELKLQSCDEYVEQPKDKGAERLQPAQIANDNAPS-- 348
            |.|||.||      :||......|.:|..|..|.|.|...|:....|  |:...|....::|:
Zfish     9 PLLPLRADMDACELRDDDKAASPDSELNEEPLLLSADTDSEEKMYGG--RVGSVQSDASSSPTEH 71

  Fly   349 -------------PLHLKLEEQDEQEQADVKDKVLELTGAAVALY----------GHLNNASKDV 390
                         |..|.:.:|.....:.|      ::|.|..|.          |||......|
Zfish    72 GHMGQSHPTYPVGPQSLLVAQQLASAVSGV------MSGGAPGLNQPILIPFNAGGHLGGQQGLV 130

  Fly   391 RDLEQCLKLQD------PNDISRLSRSPSPLQSNASDCDDNNSSVGTSSDRCRSPLSPALSLSHQ 449
            ..|.....:|.      ...|..|     |||:                      |....||:.|
Zfish   131 LSLPTAANIQGLVAAAAAGGIMAL-----PLQN----------------------LQATSSLNSQ 168

  Fly   450 -QAKRQLMSLQPH--PAHHHHNPH----------------------------------------- 470
             |..:||..||.|  ..||||...
Zfish   169 LQHLQQLQQLQHHQQQQHHHHQQQQQQQQREREREREREREQREREQRERDQQREREQHQQLCGQ 233

  Fly   471 -HLNHLNHHQYKQ--EEDYDDANGGALNLTSDNSRHSTQSPSNSVKSATASPVPVISVPSPVPPM 532
             ||...:|||...  :......:.|.:. |...|.||:..|..|..|...:..|..|:||||.|.
Zfish   234 AHLQPPSHHQLTPPIQSQVSGPSPGPVP-TCPPSNHSSAQPPQSPPSHRQNQSPARSLPSPVTPP 297

  Fly   533 ISPV--------------------LAPSGCGSTTPNSMAAAAAAAAAVASTMGS-----GISPLL 572
            : |:                    ..||  ....|.:..||.|||||:.|..||     .:|.|.
Zfish   298 L-PLQGNAFHLLRQRESEGERKRECLPS--DRLNPLASQAAVAAAAAMGSIAGSQVFGNALSSLQ 359

  Fly   573 ALPGMSSPQAQ--------LAAAGLGMNN-------PLLTGSLSPQDFAQFHQLL--QQRQVALT 620
            .:.|.....||        |....:|.:|       ||....::|       |||  .|.|:..|
Zfish   360 GVTGQLVTNAQGQIIGTIPLMPNSVGPSNQSGGGTSPLQVQPITP-------QLLTNAQGQIIAT 417

  Fly   621 QQFNSYMELLRSGSLGLAQDDPALTAQVAAAQFLMQSQLQALSQASQQLQALQKQQQRQVDEPLQ 685
            ...|..:.::.:..:.|:...|.                |.|.|..|..||
Zfish   418 VIGNQILPVINTQGITLSPIKPG----------------QQLPQTGQTPQA-------------- 452

  Fly   686 LNHKMTQQPRSSTPHSIRSPIAIRSPASSPQQLHHHHHHPLQITPPSSAASLKLSGMLTPSTPTS 750
                    |..|.|:.:|.|               |...||:....||:.|           .:|
Zfish   453 --------PPVSQPNLLRMP---------------HSQSPLRQASSSSSTS-----------SSS 483

  Fly   751 GTQMSQGTTTPQPKTVASAAAARAAGEPSPEETTDLEELEQFAKTFKQRRIKLGFTQGDVGLAMG 815
            .:.:|.|.....|:|.           ||..:..:|||:.:|||.||.||:.||.||..||.|:.
Zfish   484 SSALSVGQLVSNPQTA-----------PSEVDGVNLEEIREFAKAFKIRRLSLGLTQTQVGQALS 537

  Fly   816 KLYGNDFSQTTI------------------------------------SRFEALNLSFKNMCKLK 844
            ...|..:||:.|                                    :|||.|:::.|:..|:|
Zfish   538 ATEGPAYSQSAICRHTILRSHFFLPQEAQENTIASSLTGKLNPGLLYPARFEKLDITPKSAQKIK 602

  Fly   845 PLLQKWLDDADRTIQATGGVFDPAALQATVSTPEIIG----RRRKKRTSIETTIRGALEKAFLAN 905
            |:|::|:.:|:...:        :.:|   :..|.||    ::||:|||........|...|..|
Zfish   603 PVLERWMAEAEARHR--------SGMQ---NLTEFIGSEPSKKRKRRTSFTPQALEILNSHFEKN 656

  Fly   906 QKPTSEEITQLADRLSMEKEVVRVWFCNRRQKEKRINPSLDSPTG 950
            ..|:.:|:|::|::|:.::|||||||||:||..|.....|..|.|
Zfish   657 THPSGQEMTEIAEKLNYDREVVRVWFCNKRQALKNTIKRLKQPEG 701

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nub	NP_001097153.1	POU	791..855	CDD:197673	28/99 (28%)
		Homeodomain	884..940	CDD:459649	24/55 (44%)
pou6f2	XP_021325963.1	PLN02226	<238..>308	CDD:177871	19/71 (27%)
		Pou	504..613	CDD:473999	31/108 (29%)
		Homeodomain	635..691	CDD:459649	24/55 (44%)