Protein Alignment Trm1 and TRM1

DIOPT Version :10

• Sequence 1: NP_609566.1
• Gene: Trm1 / 34656
• FlyBaseID: FBgn0032430
• Length: 578
• Species: Drosophila melanogaster
• Sequence 2: NP_010405.3
• Gene: TRM1 / 851698
• SGDID: S000002527
• Length: 570
• Species: Saccharomyces cerevisiae
• Alignment Length: 534
• Identity: 198/534 - (37%)
• Similarity: 306/534 - (57%)
• Gaps: 26/534 - (4%)

  Fly     8 PQIIAENPNENVIRERNAEIV--SGGNVFYNPVQEFNRDLSIAAL----NVYRQRLTKERSEKAL 66
            |:|..|  :.|:::|..|||:  ....|||||:|:||||||:..:    |:|.:...::|:.|..
Yeast    35 PRINIE--DFNIVKEGKAEILFPKKETVFYNPIQQFNRDLSVTCIKAWDNLYGEECGQKRNNKKS 97

  Fly    67 KKQRKKVKEQEDEKTTPVPEDPPVYEAG--TRYEDGLRILEALAATGLRSIRYAQEIAGVRQIVA 129
            ||:|......:..|...:....|....|  .|.|..:.|||||:|||||:||||.||..||:::|
Yeast    98 KKKRCAETNDDSSKRQKMGNGSPKEAVGNSNRNEPYINILEALSATGLRAIRYAHEIPHVREVIA 162

  Fly   130 NDLSRQAVASINTNIRHNKVEELIEPSHSDAMTLMYLSTQPEKRFDAVDLDPYGCPNRFLDGAMQ 194
            |||..:||.||..|:.:|.||.:::|:..||..|||.:.....:|..:||||||....|:|.|:|
Yeast   163 NDLLPEAVESIKRNVEYNSVENIVKPNLDDANVLMYRNKATNNKFHVIDLDPYGTVTPFVDAAIQ 227

  Fly   195 CLVDGGLLLVTATDMAVLAGNA-PEACYVKYGSVPL-RMKCCHEMALRILLHCIESHANRYGKYI 257
            .:.:|||:|||.||::|||||. ||.|:..||...: ..:..||.|||::|:.::..|.:|.|.:
Yeast   228 SIEEGGLMLVTCTDLSVLAGNGYPEKCFALYGGANMVSHESTHESALRLVLNLLKQTAAKYKKTV 292

  Fly   258 EPLLSISADFYIRIFVRVYVGQAQCKLSMSKQSWIYQCTGCETFTLQPLGITKPNPTAGNPQQLK 322
            |||||:|.|||:|:||:|.....:.|..||.....|.|:.|.::..||||.........|....|
Yeast   293 EPLLSLSIDFYVRVFVKVKTSPIEVKNVMSSTMTTYHCSRCGSYHNQPLGRISQREGRNNKTFTK 357

  Fly   323 FGIPTGPAVNSQCEHCGHRHHLGGPIWSAPIHNPEFVQDLLTAVQETTL---QSLGTQRRIVGVL 384
            :.:..||.|:::|:.|...:||.||:::.|:||.||::::|...:|...   .:.||::||.|:|
Yeast   358 YSVAQGPPVDTKCKFCEGTYHLAGPMYAGPLHNKEFIEEVLRINKEEHRDQDDTYGTRKRIEGML 422

  Fly   385 SMVQEELQDVPLYYTPDKLCCVLKLEIVPMLKFRSAILHAGYRVSYSHASKNSLKTNAPPAVLWD 449
            |:.:.||.|.|.|::|:.:..|:||::.|:.|..:.:...|:..|.:||..:|||||||...:|.
Yeast   423 SLAKNELSDSPFYFSPNHIASVIKLQVPPLKKVVAGLGSLGFECSLTHAQPSSLKTNAPWDAIWY 487

  Fly   450 IL-------RSWSKRHP-VNPERMIPGSP--LAAILSKECTAVYEFDELHPEAN-PKSRKSALSR 503
            ::       :..||.:| ....:::...|  |:..:..|..:...|.......| .|.||..:.|
Yeast   488 VMQKCDDEKKDLSKMNPNTTGYKILSAMPGWLSGTVKSEYDSKLSFAPNEQSGNIEKLRKLKIVR 552

  Fly   504 FQENPTPHWGPGTR 517
            :|||||.:|||..|
Yeast   553 YQENPTKNWGPKAR 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trm1	NP_609566.1	AdoMet_MTases	17..452	CDD:473071	174/454 (38%)
TRM1	NP_010405.3	TRM1	45..495	CDD:273006	173/449 (39%)