Protein Alignment Fam92 and CIBAR1

DIOPT Version :10

• Sequence 1: NP_609564.1
• Gene: Fam92 / 34654
• FlyBaseID: FBgn0032428
• Length: 395
• Species: Drosophila melanogaster
• Sequence 2: NP_660312.2
• Gene: CIBAR1 / 137392
• HGNCID: 30452
• Length: 289
• Species: Homo sapiens
• Alignment Length: 316
• Identity: 94/316 - (29%)
• Similarity: 161/316 - (50%)
• Gaps: 33/316 - (10%)

  Fly     1 MFRRGKLSFLNTKDDRVKIINERINITERHLMEMCSSFALVTRKMAKYRDSFDELAKSVKSYADD 65
            |.||    .|..::.:.|.:...::..|:|..|:|..||...||.|:.||..|.|...:.:||..
Human     1 MMRR----TLENRNAQTKQLQTAVSNVEKHFGELCQIFAAYVRKTARLRDKADLLVNEINAYAAT 61

  Fly    66 EEINESLCQGLKSFTNAVTIMGDYMDINVHRLEHKIVNELAQFEQLCKSTRDNLRLAVIARDKEV 130
            |..:..|  ||.:|.:....:.||....|.|||.|:|..|..:..:.|..||:|:..:.||::|.
Human    62 ETPHLKL--GLMNFADEFAKLQDYRQAEVERLEAKVVEPLKTYGTIVKMKRDDLKATLTARNREA 124

  Fly   131 LRQRQMLELKSKFSANN---SAADSELFKAKMEVQRTNKEIDDIIGNFEQRKLRDLKQIISDFIL 192
            .:..|:...:.:..::.   |.|::||.:|.|:..||::.:::.|.|||::|::|:|.|.|:||.
Human   125 KQLTQLERTRQRNPSDRHVISQAETELQRAAMDASRTSRHLEETINNFERQKMKDIKTIFSEFIT 189

  Fly   193 IAMKQHTKALEILSASYYDIGTIDERDDFIEFQKLMKTKEELASRKTALKKGLRSQSMDSLEHEH 257
            |.|..|.||||:.:|:|.:|..|||.:|...|:..:.. .:.:||...::...:
Human   190 IEMLFHGKALEVYTAAYQNIQNIDEDEDLEVFRNSLYA-PDYSSRLDIVRANSK----------- 242

  Fly   258 LVSPLKRRPKLSRSNRNLTGAGINHGSKTEPEDETDEQDEEEDDEDEETEQSGEED 313
              |||:|    |.|.:.::|.|.....:...:.:.      |||||:|.:.:.||:
Human   243 --SPLQR----SLSAKCVSGTGQVSTCRLRKDQQA------EDDEDDELDVTEEEN 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fam92	NP_609564.1	FAM92	1..222	CDD:284207	75/223 (34%)
CIBAR1	NP_660312.2	BAR_FAM92	8..218	CDD:153282	70/211 (33%)
		BAR-like. /evidence=ECO:0000305|PubMed:27528616	10..220		71/211 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	265..289		8/28 (29%)