DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6712 and Rpf1

DIOPT Version :9

Sequence 1:	NP_477479.1	Gene:	CG6712 / 34631	FlyBaseID:	FBgn0032408	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	XP_036019195.1	Gene:	Rpf1 / 70285	MGIID:	1917535	Length:	352	Species:	Mus musculus

Alignment Length:	382	Identity:	154/382 - (40%)
Similarity:	218/382 - (57%)	Gaps:	70/382 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IKRKTAPPPVEQDSDSDSSFDEEEPQDLEVQEGPVTDSSDEEAASSSKKTAKQGEASEDLKEEDD 68
            :|||.|               .||||               |||::|..||:.|.
Mouse    16 LKRKAA---------------AEEPQ---------------EAAAASDGTAESGV---------- 40

  Fly    69 DDDEEENDDDDEEEDDDDDDDKKTRIPVLNPLSWMRNKEQRLALYKKMKKEKHKKKM-------Q 126
                              ...|....|....:|.::||::|..::.:.|:::.|:|:       :
Mouse    41 ------------------QPAKAAAFPPGFSISEIKNKQRRHLMFTRWKQQQRKEKLAAKKKLKK 87

  Fly   127 ERRARRKAGVPANPGHTIESLREKDQTEVANLNDSDNEELQKELQLDDFSSYFERSYEPKVLITF 191
            ||.|......|.....||::.|..|:|.|    |.::||:..:...|:|:|||.|...||:|||.
Mouse    88 EREALGDKAPPKPVPKTIDNQRVYDETTV----DPNDEEVAYDEATDEFASYFNRQTSPKILITT 148

  Fly   192 ADNPVTKTRKFGLELSRIFPNALVKIRNKSSVKKICKSAEREEFTDVVIVNEDRRKPNGLLVIHL 256
            :|.|..:|.:...:||.:.|::.|..|...::|||.......:|||::::||||:.||||::.||
Mouse   149 SDRPHGRTVRLCEQLSTVIPDSHVYYRRGLALKKIIPQCIARDFTDLIVINEDRKTPNGLILSHL 213

  Fly   257 PNGPTAHFKLSNVKLTSDIKRDHKEITKHRPEVILNNFTTRLGLTVGRMLGALFHHDPEFRGRRA 321
            |||||||||:|:|:|..:|||..|:.|:|.||:||||||||||.::|||..:||.|:|:|.||:.
Mouse   214 PNGPTAHFKMSSVRLRKEIKRRGKDPTEHVPEIILNNFTTRLGHSIGRMFASLFPHNPQFIGRQV 278

  Fly   322 VTFHNQRDYIFFRHHRYEFTKEGKRVKLRELGPRFTLKLRSLQEGTFDSKTGDYAWI 378
            .||||||||||||.|||.|..| |:|.::||||||||||||||:||||||.|:|.|:
Mouse   279 ATFHNQRDYIFFRFHRYIFKSE-KKVGIQELGPRFTLKLRSLQKGTFDSKYGEYEWV 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6712	NP_477479.1	Brix	188..358	CDD:214879	92/169 (54%)
Rpf1	XP_036019195.1	Brix	145..314	CDD:214879	92/169 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837913
Domainoid	1	1.000	194	1.000	Domainoid score	I3176
eggNOG	1	0.900	-	-		E1_COG2136
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68728
Inparanoid	1	1.050	277	1.000	Inparanoid score	I2922
Isobase	1	0.950	-	0	Normalized mean entropy	S689
OMA	1	1.010	-	-		QHG53520
OrthoDB	1	1.010	-	-		D768872at2759
OrthoFinder	1	1.000	-	-		FOG0004778
OrthoInspector	1	1.000	-	-		oto92640
orthoMCL	1	0.900	-	-		OOG6_102467
Panther	1	1.100	-	-	LDO	PTHR22734
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1780
SonicParanoid	1	1.000	-	-		X3362
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	16.750