DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Wdr81 and CG7568

DIOPT Version :9

Sequence 1:	NP_609535.1	Gene:	Wdr81 / 34616	FlyBaseID:	FBgn0032395	Length:	1953	Species:	Drosophila melanogaster
Sequence 2:	NP_001263071.1	Gene:	CG7568 / 43482	FlyBaseID:	FBgn0039673	Length:	482	Species:	Drosophila melanogaster

Alignment Length:	367	Identity:	78/367 - (21%)
Similarity:	128/367 - (34%)	Gaps:	104/367 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly  1535 MKRTLSNLD----------FVLTLCHEHEQPNGQSKIQLATNVS---SGQD--VDSVDASCELAA 1584
            :|:.|..|.          |.|..||       .|.|...||||   ||:.  ..|.|.:|.: .
  Fly    89 LKQALEKLQKKLREPVKKKFYLHKCH-------NSHILPLTNVSFDRSGERCLTGSYDRTCHV-I 145

  Fly  1585 NSFGTQIVGNRLQVARNNVELIDMVAYKLDQMPKTRHLKGNWLAYWRNETTRNEKDTQTLNLKQI 1649
            |:...|:  ..:....:||  :..|.:...          :||.|
  Fly   146 NTQTAQV--EHILSGHDNV--VFSVGFNFP----------HWLVY-------------------- 176

  Fly  1650 RLQSFVGHTNSVRAIYALDNENSFISASKDKTVKLWSLRSEGDGRKTSACQFTYTAHKKSINSLG 1714
             |||  |.:.:....:::...:..::.|.|.|.|:||..|   |:  |.|  |:..|...:.:..
  Fly   177 -LQS--GGSGNNLTTFSIIFSDKIVTGSFDGTAKVWSATS---GQ--SLC--TFYGHTAELVAAE 231

  Fly  1715 FL----ESLRYVVSCDSGIHLWDPFIGRPLSVLDAPRHSAVTVVKCLPSHSPLVIAGTAESTVKM 1775
            |.    :|:. ..|.|....::|......|..|  ..|.|..:.........:::.|:.:.:..:
  Fly   232 FHPVDGKSIA-TASLDGSARIYDVETSHELQQL--THHGAEVIAARFNRDGQMLLTGSFDHSAAI 293

  Fly  1776 VDARSCEYVNEWRVCNASLPNATVRCLAVAPSGNWLAAGLSSGCIVQLDTRTGMVINSW--RPME 1838
            .|.||....::.|..:|.|.|.....     ||:.:|.|       .||....:    |  |.::
  Fly   294 WDVRSKSLGHQLRGHSAELSNCVWNF-----SGSLIATG-------SLDNTARI----WDTRKLD 342

  Fly  1839 CDLLQLAAPSD-----------QFLVSSALDHSLAVWHALDG 1869
            .:|...|..||           |.|.:.:.|.:..||. |:|
  Fly   343 QELYLAARHSDEVLDVSFDAAGQLLATCSSDCTARVWR-LEG 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wdr81	NP_609535.1	Beach	345..588	CDD:100117
		WD40	<1644..1877	CDD:225201	52/243 (21%)
		WD40	1651..1876	CDD:295369	52/236 (22%)
		WD40 repeat	1662..1705	CDD:293791	11/42 (26%)
		WD40 repeat	1710..1744	CDD:293791	6/37 (16%)
		WD40 repeat	1752..1788	CDD:293791	4/35 (11%)
		WD40 repeat	1799..1836	CDD:293791	7/38 (18%)
CG7568	NP_001263071.1	WD40	93..466	CDD:225201	77/363 (21%)
		WD40 repeat	122..158	CDD:293791	11/38 (29%)
		WD40	154..467	CDD:238121	58/292 (20%)
		WD40 repeat	189..222	CDD:293791	11/39 (28%)
		WD40 repeat	228..265	CDD:293791	7/39 (18%)
		WD40 repeat	270..306	CDD:293791	4/35 (11%)
		WD40 repeat	314..348	CDD:293791	10/49 (20%)
		WD40 repeat	355..393	CDD:293791	7/30 (23%)
		WD40 repeat	400..436	CDD:293791
		WD40 repeat	442..466	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442335
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930