Protein Alignment Wdr81 and AT5G18525

DIOPT Version :10

• Sequence 1: NP_609535.1
• Gene: Wdr81 / 34616
• FlyBaseID: FBgn0032395
• Length: 1953
• Species: Drosophila melanogaster
• Sequence 2: NP_974804.4
• Gene: AT5G18525 / 2745988
• AraportID: AT5G18525
• Length: 1639
• Species: Arabidopsis thaliana
• Alignment Length: 2029
• Identity: 448/2029 - (22%)
• Similarity: 702/2029 - (34%)
• Gaps: 709/2029 - (34%)

  Fly   112 HSNFKQLWEEAYRKYNGAHVRMCRSTPSAPSTKPPSGQGQLQPHDVVLKELIQRV-YRCP----- 170
            ||.....|.........|.:|.|.::.                    |::|.... |.||
plant   133 HSGSFSCWRTVAALLPIAQIRKCSASE--------------------LQKLASSFHYECPEDQIL 177

  Fly   171 -VLHCQLDRDGVSDSSNATSC-----------SAGSC--HANVLPALVAIETSTHISVFFYPPA- 220
             .||..:|......::::..|           |...|  |.|:.|.| .:.||:...|...|.|
plant   178 ASLHRLIDGKSSGQATHSFLCLLLGLPLLEEKSKLRCLRHPNLSPVL-GLLTSSDCLVSVLPKAP 241

  Fly   221 --LECSLYDCITFSPALLGKNYNKTLFVIYQILQLAKHLQGQGLFLGDLRLQDIVLRENLWLQVL 283
              ||..||    :||:.:...:::. |:|||:|....||.|..:..||:|..:|:|.::||
plant   242 YTLENILY----YSPSAIKSEWHRN-FIIYQLLSALAHLHGLKVSHGDIRPSNILLSDSLW---- 297

  Fly   284 PRLQCNLLDDDPAGEDMSPLTPLVSEDLGEA---------REAQQALPSSSTMFDLRFAYDPAHF 339
                             |.||.....|||..         |...:...|.....||:.:   :|.
plant   298 -----------------SWLTIYSKPDLGSVDANSSASRRRWCVEGCYSYGLYADLKIS---SHL 342

  Fly   340 NLREYTEMWCNGQLSNFDYLTILNNACGRSLTNAAYHHIMPWVTDFSGR----GGGAWRDLTKSK 400
            :.:.:.:.|..|:||||:||.:||...||...:..:|.:||||.|||.:    ....||||.|||
plant   343 DWQTHFDKWWKGELSNFEYLLVLNKLAGRRWGDHTFHPVMPWVIDFSKKPENDSDSGWRDLRKSK 407

  Fly   401 YRLNKGDVHLDLMYAHASQHGSADGSYQAIGDQAPHHVSD-FLSEITYFVYMARRTPQSILCAHV 464
            :||.|||..||..|:..               :.|||||| .|||:....|.|||.|.|:|...|
plant   408 WRLAKGDEQLDFTYSTF---------------EFPHHVSDECLSELAVCSYKARRLPLSVLRKAV 457

  Fly   465 RPIWVPAEYPVSIQRLQEWTPDECIPEFYSDPMIFKSIHEDLPDLELPAWATCPEDFICKHREAL 529
            |.::.|.|||..:|||.:|||||||||||.||.||.|:|..:.||.:|.||:.|::||..||:||
plant   458 RSVYEPNEYPSDMQRLYDWTPDECIPEFYCDPRIFCSLHPSMSDLAVPPWASSPDEFIRLHRDAL 522

  Fly   530 ESQYVSERLHHWIDLNFGYKLSGKAAVKSKNVCLTLVDQ--HRNLSQRGIVQLFASAHPPRRYAT 592
            ||.:||..:|||||:.||||:||.||:.:|||.|:..:.  .|::.:|   |||...||.|.
plant   523 ESPHVSSLIHHWIDITFGYKMSGHAAITAKNVMLSSSEPTVPRSVGRR---QLFFRPHPVRL--- 581

  Fly   593 PWFSRTAPRLSQLYASPAKRLAKSTENLQAESATG----SSHLSLRLGD----DGSSGSVHSSSA 649
             .|||              ...:|...|:..:..|    :....:.|.|    :....|..|..|
plant   582 -GFSR--------------EKEQSRNELEMHTFHGFGVDNKRSVILLADEYLEETEEASAFSDHA 631

  Fly   650 SASASNFYAITNFIELPENYNPALLLHNLETLEAFYARTFPQQRAS--ANPEEKMISSDLMFEQN 712
            :.....::...|.:|.|              |...|:....:...|  ...:.|.:||.:....
plant   632 THLCPKYHLRENLVESP--------------LHVSYSENTKKVNTSLPGTSKNKGLSSRISLNY- 681

  Fly   713 SAEHSFTNQLFASGDELPPKSKNLLREKRN-CLQHLLNVRKE--RDLHVLGCLIIELFAMQRLRP 774
            ..||....      ||...:.:.||:.::: |..   |:.|:  .|:..:||::.||:.|   :|
plant   682 LLEHMEVR------DEASTELQELLQWRQDFCTG---NISKDIAGDIFSIGCVLAELYLM---KP 734

  Fly   775 LLMGNGLTATFDSRLSACRTVAQLHRQELPKPVRRVVRLLLQLEQPGEEDQGLPQPPNPAQLLE- 838
            |.....|....:.     ..:.:|.: |||.|.:.:|...:        :|...:.|:...||:
plant   735 LFNSVSLATYLEG-----GDLPELIK-ELPPPTQVIVEACI--------EQDWRRRPSAKSLLDS 785

  Fly   839 PMFSNLLLPFPSHYMAVYALVRSLHAFEANAVLLELQTHFSCKGGRECERYTEMDRQRVLFERKI 903
            |.||              |.|||.|.|.|...||       .||...........:|.||   |:
plant   786 PYFS--------------ATVRSAHLFAAPLQLL-------AKGQTRLCYAASFAKQGVL---KV 826

  Fly   904 AECKVMSCCAHVKRLLEPMSFAYEQFTPVELLLPHIIDLLRDERTSILTAWNLFDPIAQALGVSQ 968
            ....|...||           .|        .||.:...|.::...:  |:.|.....::|....
plant   827 MGTFVAEMCA-----------VY--------CLPLVTTPLSEDECEL--AYVLLKEFTKSLTPMA 870

  Fly   969 TQQHLLQPLLKLYDVESVSSPDDGGSNGSTNSGGHLRFSASSSFKSRKSVKLYHHSFLLRLIVRF 1033
            .|:.:|..:.|:.               .|....||:            |.|...||:..|..:.
plant   871 VQRLVLPSIQKIL---------------LTTGYSHLK------------VSLLQDSFVRELWNQI 908

  Fly  1034 GLRCFLHHFIAPLIEAVGGYKEPEQGNGYHYHSGGSRRTSKNLNFASENEVHQTEVAPEMKPDIE 1098
            |.|.:| ..|.||:                                                 |.
plant   909 GKRVYL-EMIHPLV-------------------------------------------------IS 923

  Fly  1099 ELFTFEDDHDRASTQDSKSIDSFDMRPSTSAASAEEARESDGSPDKLVINELIYGARISPDKLSL 1163
            .|:.                                                      ||||:|
plant   924 NLYN------------------------------------------------------SPDKIS- 933

  Fly  1164 KESQTPPALVPPPIGPRSPTIEIPMGPTAGGIRRSFQLSAIDCDIGSRKSVDSFDLISQAVEQLP 1228
                                                                             
plant   934 ----------------------------------------------------------------- 933

  Fly  1229 PPAEESEAEASDSLQASVISRLSEAKAVQNNRISEMSAESLVWLSHRLGPVLTSRFITRNLLKLL 1293
                   |.|     |||:                     |:..|..||..:|   :.:.:|.|:
plant   934 -------ASA-----ASVL---------------------LIGSSEELGAPVT---VHQTILPLI 962

  Fly  1294 SLCYVGQENLLPEVDDGGSSFNSSPDAANLNYFSIANARVVGDRSAARVLECLMSIAALYGENFL 1358
            |                              ||        |.......::.|:.|..|.|.||:
plant   963 S------------------------------YF--------GKGICTDGIDVLVRIGRLLGVNFI 989

  Fly  1359 LLQYFPHISELI----------------SLCSKRITG---SLEG--AIISSLQLLKYMVPCLTDA 1402
            :.|..|.:..::                |.||..::.   :|:|  |:||.    :.::..||..
plant   990 VKQMLPLLEHVVCFCIDLSSMKKPEPVHSWCSLALSDCLITLDGLVALISD----ELLIHELTKG 1050

  Fly  1403 SIMEHLQHIMLDAILLPILRLLSSTNLVMPSGYLGRSLLARKFLDAIYALSVRLGSDMTREHLCQ 1467
            .:..|::.:|...:.|.:|: .::|:|:                    ::..|:|.:||..|:.
plant  1051 RLCLHVRVLMQKNLELRVLQ-FAATSLM--------------------SICQRIGQEMTALHVL- 1093

  Fly  1468 PLLNPFFLIFNKAFGLPNDFACDLANLS-LVGGASQ---PERALEELRDVFGPELAHTAYLTFLR 1528
            |.|...|..|  ||...:..|.|  :|| .:..|.|   ||..::...|     |....|.:|..
plant  1094 PQLKELFDEF--AFSEKSTDASD--SLSWKIRTAEQKFHPESPIKSRMD-----LVLLLYPSFAS 1149

  Fly  1529 FLGEANMKR---TLSNLDFVLTLCH--EHEQPNGQSKIQLATNVSSGQDVDSVDASCELAANSFG 1588
            .||...:::   |...|:..|...|  :.|.....|:..:.......|...|.... ::..|..|
plant  1150 LLGMEKLRQGCPTWLLLEQYLLKHHNWKWEYTGRSSRYNMEARPVLKQGPASKHTP-KVLLNGSG 1213

  Fly  1589 TQIVGNRLQVARNN----------VELIDMVAYKLDQMPKTRHLKGNWLAYWRNETT-------- 1635
            ..:  .:.|..||:          ||..:.|...|...|        | :::.:..|
plant  1214 RSV--PQSQGLRNSNHLKLHIHVPVEGQEAVLNPLVHEP--------W-SWFPSPVTCWDGLDIG 1267

  Fly  1636 --RNEKDTQTLNLKQIRLQSFVGHTNSVRAIYALDNENSFISASKDK----TVKLWSLRSEGDGR 1694
              .|.||.....::...|.|...|..::|::...::|.:..::..|.    :|:.|.|.|
plant  1268 RFGNPKDENRWKIRASVLSSARAHHGALRSLVVSEDECTVFTSGIDPGFKGSVQKWELAS----- 1327

  Fly  1695 KTSACQFTYTAHKKSINSLGFLESLRYVVSCDSGIHLWDPFIGRPLSVL-DAP------------ 1746
              .:|..:|.||::.:|.:|.|.|...|.|||..||:|:...|:.:|:. ::|
plant  1328 --LSCVSSYHAHEEVVNDIGILSSTGKVASCDGTIHVWNSQTGKLISLFSESPSDQDQASSDPSS 1390

  Fly  1747 --------RHSA---------VTVVKCLP--SHSPLVIAGTAESTVKMVDARSCEYVNEW----- 1787
                    ||::         ..:..|:.  .:...:|.||....::.:|....:.:..|
plant  1391 KNNSNPCNRHASHGLSSGIFDENLYTCMHYLEYMDQLIVGTGFGALRFIDLARGQKLELWGGEAI 1455

  Fly  1788 ---------RVCNASLPNATVRCLAVAPSGNWLAAGLSSGCIVQLDTRTGMVINSWRPMECDLLQ 1843
                     .:|:...........:|:||  |:|||.|||.....|.|....|:|||..:..:.:
plant  1456 ESGFTSLVSALCSGGSQTKHGDGASVSPS--WIAAGFSSGQCRLFDLRENGFISSWRAHDGYVTK 1518

  Fly  1844 LAAPSDQFLVSSALDHSLAVWHAL--------------DGIMHYQL------------------- 1875
            |.||....||||:||.:|.:|...              ||:..:.:
plant  1519 LVAPESHLLVSSSLDKTLRIWDLRKSWTPQPFVVKGHNDGVSGFSIWGKDVISISRNNIGIFSLA 1583

  Fly  1876 KPPPEPAHFLQSVGPSLVY-ATTGNRVGVYADVAHSHAFSTITKLRSETFRGVLTSLAVLPLNRA 1939
            |...|.....|.:.|..:| |..|.||                       :..|:::.|||.:|.
plant  1584 KSQDEEEQQQQRIIPQKLYMAEKGGRV-----------------------KSDLSTICVLPFSRL 1625

  Fly  1940 FLAGNESGNIALLC 1953
            |:.|...|::.:.|
plant  1626 FIVGAHDGHLRICC 1639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wdr81	NP_609535.1	Beach	345..588	CDD:100117	117/249 (47%)
		WD40	1651..1876	CDD:475233	66/307 (21%)
		WD40 repeat	1662..1705	CDD:293791	9/46 (20%)
		WD40 repeat	1710..1744	CDD:293791	13/34 (38%)
		WD40 repeat	1752..1788	CDD:293791	6/51 (12%)
		WD40 repeat	1799..1836	CDD:293791	15/36 (42%)
AT5G18525	NP_974804.4	PHA03209	118..>294	CDD:177557	45/186 (24%)
		Protein Kinases, catalytic domain	207..>295	CDD:473864	30/93 (32%)
		Protein Kinases, catalytic domain	<264..>330	CDD:473864	21/86 (24%)
		Beach	349..580	CDD:100117	117/248 (47%)
		Pkinase	<714..788	CDD:459660	20/90 (22%)
		WD40	<1285..1576	CDD:441893	66/299 (22%)
		WD40 repeat	1296..1336	CDD:293791	9/46 (20%)
		WD40 repeat	1341..1375	CDD:293791	13/33 (39%)
		WD40 repeat	1416..1456	CDD:293791	6/39 (15%)
		WD40 repeat	1463..1510	CDD:293791	15/48 (31%)