Protein Alignment Wdr81 and mv

DIOPT Version :10

• Sequence 1: NP_609535.1
• Gene: Wdr81 / 34616
• FlyBaseID: FBgn0032395
• Length: 1953
• Species: Drosophila melanogaster
• Sequence 2: XP_061497088.1
• Gene: mv / 1273970
• VectorBaseID: AGAMI1_009850
• Length: 3691
• Species: Anopheles gambiae
• Alignment Length: 1263
• Identity: 255/1263 - (20%)
• Similarity: 406/1263 - (32%)
• Gaps: 480/1263 - (38%)

  Fly    20 EAGGDGRFQVICD----KAWLQSLERNRRLTHFPSWPLLDRRSYPI--------------GQLEH 66
            |:||: ....|||    |.::||:            .||:::..|:              |.|.|
Mosquito  2614 ESGGN-HLSAICDVKMLKVFVQSI------------LLLNQKHIPLEDLRLVNAFYQSIDGGLSH 2665

  Fly    67 PWTRILVQTYR-----------KQPQSRVYPLPRISGDAPSSELPLSYS---QAVSFVAHSNFKQ 117
            ..:..|.||.:           .|.|:.:..:.|        :..|.||   .|:....:|..||
Mosquito  2666 GASWNLTQTLKDFEYLRAISMNDQEQTIMKSIAR--------QEKLIYSCTVAAMQITRNSVEKQ 2722

  Fly   118 --LWEEA---------YRKYNGAHVRMCRSTPSAPSTKPPSGQGQLQPH----------DVVLKE 161
              |.:|.         ||.|:..|..:.|.|    ....|....:|.|.          |:.||
Mosquito  2723 NRLRKELIIQLRKDNDYRFYDQWHRLVDRMT----HDDAPWYNARLYPSSWELDDTYGPDMALK- 2782

  Fly   162 LIQRVYRCPVLHCQLDR------------DGVSDSSNATSCSA----------GSCHANVLPALV 204
               |:.|||:   .:||            .|..:....|...|          .|....||....
Mosquito  2783 ---RMRRCPM---TIDRRFLLKETVPESKHGAEEEREQTPLLAYLFSNDYRHEYSVEDQVLYTFT 2841

  Fly   205 AIETSTHISVFFYPPAL--ECSLYDCITFSPALLGKNYNKTLFVIYQILQLAKHLQGQGLFLGDL 267
            ..:||         |:.  ||   :||..|..|:.|.|:                      .|:|
Mosquito  2842 VRKTS---------PSYEQEC---ECIITSTELVLKPYD----------------------AGEL 2872

  Fly   268 RLQDIVLRENLWLQ--------VLPRLQCNLLDDDPAGEDMSPLTPLVSEDLGEAREAQQALPSS 324
            .:.|:.....:|.:        |...|:|.           ..|..:...|           ||.
Mosquito  2873 EIYDLHDITKIWTKRYEHQESAVEVFLKCG-----------KSLFIVFHRD-----------PSE 2915

  Fly   325 STMFDLRFAYD----PAHFNLREYTEMWCNGQLSNFDYLTILNNACGRSLTNAAYHHIMPWV-TD 384
            ...|: .|.:|    .....|..||:.|..|.|||::||.:||...||:..:...:.:.||| .:
Mosquito  2916 RDTFE-GFFHDLVVRCGRQELDHYTQQWREGALSNWEYLMLLNQIAGRTYHDLMQYPVFPWVLAN 2979

  Fly   385 FSGR-----GGGAWRDLTK---------SKYRLNKGDVHLDLMYAHASQHGSAD--GSYQAIGDQ 433
            :..|     ...::|.|.|         .|:.:|.        |.|..|..|.|  |..:.|  |
Mosquito  2980 YDTRTLDLLAERSFRVLEKPIAVQHRELEKHYINN--------YNHLRQAESGDPNGGRRKI--Q 3034

  Fly   434 APHHVSDFLSEITYFVYMARRTPQSILCAH---------------VRPIW--VPAEYPVSIQRLQ 481
            ..|:.|.:.:..|...::.|..|.:.|...               ::..|  ...:.|..::
Mosquito  3035 PYHYSSHYSNSGTVLHFLVRVLPFTSLFLQYQDDSFDIPDRTFHSLQTTWNLASKDSPTDVK--- 3096

  Fly   482 EWTPDECIPEFYSDPMIFKSIH----------EDLPDLELPAWATCPED---FICKHREALESQY 533
                 |.||||::.|...::..          |.:..:|||||  |...   |:..||:|||:..
Mosquito  3097 -----ELIPEFFTFPEFLENQEGFDFGTRQSGEPVNHVELPAW--CGGSARLFVLIHRQALEANI 3154

  Fly   534 VSERLHHWIDLNFGYKLSGKAAVKSKNV------C----------------LTLVDQHRNLSQRG 576
            |..:|.|||||.||||.||:||:.:.||      |                .|:|..:..:.:|
Mosquito  3155 VRRQLSHWIDLIFGYKQSGQAAIDAINVFHPATYCDFTASDIDDPVMKLALETMVKTYGQMPRR- 3218

  Fly   577 IVQLFASAHPPRRYATPWFSRTAPRLSQLYASPAKRLAKSTENLQAESATGSSHLS-LRLGDDGS 640
               ||.:.|||            |.::.|.|:|.|.| :|...|:.....||..|| .||.|...
Mosquito  3219 ---LFDTPHPP------------PAMNPLVANPPKVL-ESVIGLRWGLYCGSPILSDPRLADVWE 3267

  Fly   641 SGSVHS---------SSASASASNFYAITNFIELPENYNPALLLHNLETLEAFYARTFPQQRASA 696
            ..|..|         :...|:.:.......|: |||..|            .|.|.|    :.:.
Mosquito  3268 KHSKESLGGIVIERGTLPPATLATLDGDKVFV-LPEKMN------------IFCATT----QGTG 3315

  Fly   697 NPEEKMISSDLMFE-------QNSAEHSFTNQLFASGDELPPKSKNLLREKRNCLQHLLNVRKER 754
            :.:...||...|.:       |::.......:||...:.:............:|......
Mosquito  3316 SKKHYTISWGEMDDRLRIRLLQDTGSTERPRELFYGSNSVAYDPITACGSDAHCTSIFFG----- 3375

  Fly   755 DLHVLGCLII---------ELFAMQRLRP--LLMGNGLTATFDSRLSACRTVAQLHRQELPKPVR 808
              |..|.:::         ..|..|.::|  .:|....:::|  |....|..|.|.|
Mosquito  3376 --HRSGRIVVFQQRSRRRRGSFFNQNMQPSVAMMSRSRSSSF--RRWIDRKSANLRR-------- 3428

  Fly   809 RVVRLLLQLEQPGEEDQGLPQ-----PPN-------PAQLLEPMFSNLLLPFPSHYMAVYALVRS 861
                   :||...:|.|..||     ||:       |.|||:
Mosquito  3429 -------RLEMDPDEQQPQPQQEQRLPPDDQIDWAYPIQLLK----------------------- 3463

  Fly   862 LHAFEANAVLLELQTHFSCKGGRECERYTEMDRQRVLFERKIAECKVMSCCA---------HVKR 917
             |....:|:                         |:..|.|||....:..||         :|:.
Mosquito  3464 -HRAPISAI-------------------------RISMEYKIAVSVSLDGCAAIWDVNSLMYVRE 3502

  Fly   918 LLEPMSFAYEQFTPVELLLPHIIDLLRDERTSILTAWNLFDPIAQALGVSQTQQHLLQPLLKLYD 982
            :.:|::..:.:.:.|                          .|:..||                |
Mosquito  3503 IPKPVNMLHSRISHV--------------------------AISPTLG----------------D 3525

  Fly   983 VESVSSPDDGGSNGSTNS-GGHLRFSASS------SFKSRKSVKLYHHSFLLRLIVRFGLRCFL- 1039
            :..|.|...|.:..:|.: ||...:|:::      ||:..::....:.:..:....|..||.:.
Mosquito  3526 IVLVHSASAGSARPATATIGGQESWSSATLVEEDDSFEVTENYNADYVNITMDTNRRDQLRLYTI 3590

  Fly  1040 ------HHFIAPLIEAVGGYKEPEQGNG 1061
                  |.|:...|:|: .|...::|.|
Mosquito  3591 NAQYVEHVFVESPIQAI-TYSTVKEGCG 3617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wdr81	NP_609535.1	Beach	345..588	CDD:100117	81/311 (26%)
		WD40	1651..1876	CDD:475233
		WD40 repeat	1662..1705	CDD:293791
		WD40 repeat	1710..1744	CDD:293791
		WD40 repeat	1752..1788	CDD:293791
		WD40 repeat	1799..1836	CDD:293791
mv	XP_061497088.1	None