Protein Alignment Wdr81 and nbeal1

DIOPT Version :9

• Sequence 1: NP_609535.1
• Gene: Wdr81 / 34616
• FlyBaseID: FBgn0032395
• Length: 1953
• Species: Drosophila melanogaster
• Sequence 2: XP_002937765.2
• Gene: nbeal1 / 100494980
• XenbaseID: XB-GENE-990549
• Length: 2716
• Species: Xenopus tropicalis
• Alignment Length: 857
• Identity: 182/857 - (21%)
• Similarity: 291/857 - (33%)
• Gaps: 297/857 - (34%)

  Fly   151 QLQPHDVVLKELIQRVYRCPVLHCQLDRDGVSDSSNATSCSAGSCHANVLPALVAIETSTHISVF 215
            |:|...:||.|           .|.|          .|...|.|.|..|        |:.||  :
 Frog  1910 QIQKEKLVLSE-----------ECDL----------ITVMDAISGHLEV--------TTQHI--Y 1943

  Fly   216 FYPPALECSLYDCITFSPALLGKNYNKTLFVIYQILQLAKHLQGQGLFLGDLRLQDIVLRENLWL 280
            |         ||..|.....:|.::...|..|.:|     ||:...|....|.: .::.:.|.:|
 Frog  1944 F---------YDGSTEKEEGVGFDFKWPLSQIREI-----HLRRYNLRRSALEI-FLIDQTNYFL 1993

  Fly   281 QVLPRLQCNLLDDDPAGEDMSPLTPLVSEDLGEAREAQQALPSSSTMFDLRFAYDPAHFNLREYT 345
            .....::         .:..|.:..|...::...|..|:.|.:|.                  .|
 Frog  1994 NFKKEVR---------NKVYSRILSLRLPNIYGTRSPQELLKASG------------------LT 2031

  Fly   346 EMWCNGQLSNFDYLTILNNACGRSLTNAAYHHIMPWVTDFSGRGGGAWRDLTKSKYRLNKGDVHL 410
            :.|.|.::||||||..||...||:..:.|.:.:.|||.          :|.|..:..||...|..
 Frog  2032 QKWVNREISNFDYLIQLNTIAGRTYNDLAQYPVFPWVL----------QDYTSEELDLNNPAVFR 2086

  Fly   411 DLM----YAHASQHGSADGSYQAIGDQAP-----HHVSDFLSEITYFVYMARRTPQSIL------ 460
            ||.    ..:..........|::..|...     |:.:.:.:......|:.|..|.:.|
 Frog  2087 DLSKPIGVVNEKNAAIVKDKYESFEDPLGTIDKFHYGTHYSNAAGVMHYLIRVEPYTTLHIQLQS 2151

  Fly   461 ----CAHVRPIWVPAEYPVSIQRLQEWTPD--ECIPEFYSDPMIFKS-----------IHEDLPD 508
                ||..:...:||.:    |.|.:...|  |.||||:..|...::           ..|.:.|
 Frog  2152 GRFDCADRQFHSIPATW----QALMDNPNDVKELIPEFFYFPEFLENKNGFDLGHLQITKEQVND 2212

  Fly   509 LELPAWATCPEDFICKHREALESQYVSERLHHWIDLNFGYKLSGKAAVKSKNV---CL------- 563
            :.||.||..|||||.|||:||||::||..||.||||.||||..|.||:::.||   |.
 Frog  2213 VILPKWAKSPEDFILKHRKALESEFVSAHLHEWIDLIFGYKQRGPAAIEALNVFYYCTYEGAVDL 2277

  Fly   564 -TLVDQHRNLSQRGIV--------QLFASAHPPRRYATPWFSRTAPRLSQLYASPAKRLAKSTEN 619
             .:.::....:..|::        ||....||.|..|           .::|...:| |...|.|
 Frog  2278 DAIANEKERKALEGMINNFGQTPCQLLKEPHPTRLSA-----------EEVYLKQSK-LDNVTLN 2330

  Fly   620 LQAESATGSSHLSLRLGDDGSSGSVHSSSASASASNFYAITNFIELPENY--------NPALLLH 676
            |........|.....:.||                  ..:...| :|:|.        :|.||:.
 Frog  2331 LFQNLPDLKSFFIEGISDD------------------VPVVKAI-VPKNQLRSFLSPGSPELLVT 2376

  Fly   677 NLETLEAF------YAR------TFPQQRASANPE-EKMISSDLMFEQNSAEHSFTNQLFASGDE 728
            ..:||...      |.|      ||.:.:...||: ::::|..                ||.|.|
 Frog  2377 VSQTLIIGTHGWLPYDRTISNYFTFSKDQTVTNPKTQRLVSGP----------------FAPGLE 2425

  Fly   729 LPPK-------SKNL--------------LREKRNCLQHLLNVRKERDLHVLGCLIIELFAMQRL 772
            :..|       .|.|              |.:.:...||:      |.:.::.||..:...:..:
 Frog  2426 ITSKLFVVSHDGKVLFSGGHWDNSIRVTSLTKGKVTSQHI------RHMDIVTCLSTDFCGIHLI 2484

  Fly   773 ----------------------RPLLMGNG---------LTATFDSRLSACRTVAQ-LHRQELPK 805
                                  :||.:..|         ::...|:.:|..:..|. :|
 Frog  2485 SGSRDTTCMIWQIGQQGGDLSSKPLQILYGHTDEITSVCISTELDTAVSGAKDGAVIIH------ 2543

  Fly   806 PVRR--VVRLLLQLEQPGEEDQGLPQPPNPAQLLEPMFSNLLLPFPSHYMAVYALV--------R 860
            .:||  .||.|              :||:.:.||..: .||.:....| :.:::.:        .
 Frog  2544 TIRRGQYVRTL--------------KPPSESSLLMSI-PNLAMSLDGH-IVIHSSIEGKSIKNKN 2592

  Fly   861 SLHAFEANAVLL 872
            :||.:..|...|
 Frog  2593 ALHLYSINGKYL 2604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wdr81	NP_609535.1	Beach	345..588	CDD:100117	85/293 (29%)
		WD40	<1644..1877	CDD:225201
		WD40	1651..1876	CDD:295369
		WD40 repeat	1662..1705	CDD:293791
		WD40 repeat	1710..1744	CDD:293791
		WD40 repeat	1752..1788	CDD:293791
		WD40 repeat	1799..1836	CDD:293791
nbeal1	XP_002937765.2	DUF4704	888..1144	CDD:374111
		DUF4800	1610..1863	CDD:374334
		PH_BEACH	1914..2011	CDD:275391	28/151 (19%)
		Beach	2032..2311	CDD:366934	84/292 (29%)
		WD40	2436..2705	CDD:392136	31/197 (16%)
		WD40 repeat	2472..2514	CDD:293791	4/41 (10%)
		WD40 repeat	2519..2556	CDD:293791	9/56 (16%)
		WD40 repeat	2564..2592	CDD:293791	3/29 (10%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D101142at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920