Protein Alignment Wdr81 and nbeal2

DIOPT Version :9

• Sequence 1: NP_609535.1
• Gene: Wdr81 / 34616
• FlyBaseID: FBgn0032395
• Length: 1953
• Species: Drosophila melanogaster
• Sequence 2: XP_031760024.1
• Gene: nbeal2 / 100486550
• XenbaseID: XB-GENE-6038810
• Length: 2788
• Species: Xenopus tropicalis
• Alignment Length: 1042
• Identity: 208/1042 - (19%)
• Similarity: 339/1042 - (32%)
• Gaps: 414/1042 - (39%)

  Fly    52 PLLDRRSYPIGQLEHP-------------WTRILVQTYRKQPQSRV---YPLPRISGDAPSSELP 100
            |..:...:.:|:||.|             |...:::|...|....:   |.||.:   .|::..|
 Frog  1699 PQKEEACFLLGKLEAPLMGSLYAKTENASWLVPIIRTLMDQCFESLELQYHLPSL---PPTNGSP 1760

  Fly   101 LSYSQAVSFV------------AHSNFKQLWEEAYRK--------YNGAHVRMCRSTPSAPSTKP 145
            ..|...::|.            .....:|..::.:.|        :|..:..:..|:....|.|
 Frog  1761 NFYDDFLTFCTTLEWRAFIDKHVQPTMEQFEKDTFAKSHHQMSLFWNSCYDALMSSSLRRESEK- 1824

  Fly   146 PSGQGQLQPHDVVLKELIQRVYRCPVLHCQLDRDGVSDSSNATSCSAGSCHANVLPALVAIETST 210
              |:.:.:..:.||:::::|                :.:.||.       :::||..:    .|.
 Frog  1825 --GESRTKFQEYVLEQVMKR----------------TKNENAR-------YSSVLKQI----NSH 1860

  Fly   211 HISVFFY-------------------PPALECSLYDCITFSPALLG--KNYNKTLFVIYQILQLA 254
            |.::...                   ||.::..:....|:|...|.  .|||         ....
 Frog  1861 HNTILRQWRSLLRLLSCPRGAWADRNPPEVKWKISSAETYSRMRLKLVPNYN---------FDPH 1916

  Fly   255 KHLQGQGLFLGDLRLQDIVLRENLWLQVLPRLQCNLLDDDPAG-EDMSPLTP------------L 306
            |....|...||....|.  |.::..|.|....:.|.::||..| ||:..:..            :
 Frog  1917 KEASAQRDNLGTDYTQS--LTDSFPLAVAKEAKVNEMEDDQLGDEDLKNMNQVETKEPNQKEKLV 1979

  Fly   307 VSEDL--------------------------GEAREAQQAL------PSSS------TMFDLR-- 331
            :|||.                          .|..|.::.:      |.|.      ..::||
 Frog  1980 ISEDCELITVVAVIPGRLEVTTQHIYFYDMSNEKEETEEGIGYDFRRPLSQLREVHLRRYNLRRS 2044

  Fly   332 ----FAYDPAHF--NLRE----------------------------------YTEMWCNGQLSNF 356
                |..|.|::  |.::                                  .|:.|...::|||
 Frog  2045 ALEFFFIDQANYFVNFKKKVRNKVYSRILGLHPLSQSTLGSRSPQEMLQALGLTQKWVWREISNF 2109

  Fly   357 DYLTILNNACGRSLTNAAYHHIMPWVTDFSGRGGGAWRDLTKSKYRLNKGDVHLDLM-------Y 414
            :||..||...||:.::.:.:.:.||:.          ||.......||..:|..||.       .
 Frog  2110 EYLMQLNTIAGRTYSDLSQYPVFPWIL----------RDYVSETLDLNNPEVFRDLSKPIGVVNE 2164

  Fly   415 AHASQHGSADGSYQAIGDQAP-----HHVSDFLSEITYFVYMARRTPQSIL----------CAHV 464
            .||.:   ....|::..|...     |:.:.:.:......||.|..|.:.|          |:..
 Frog  2165 KHARE---VKEKYESFEDPTGTVDKFHYGTHYSNAAGVMHYMIRMEPFTTLHIQLQSGRFDCSDR 2226

  Fly   465 RPIWVPA------EYPVSIQRLQEWTPDECIPEFYSDPMIFKSIHE-DL----------PDLELP 512
            :...:||      |.||.::        |.||||:..|...::.:. ||          .|:.||
 Frog  2227 QFHSIPAAWQARMENPVDVK--------ELIPEFFYFPEFLENANGFDLGCLQISNGKVNDVVLP 2283

  Fly   513 AWATCPEDFICKHREALESQYVSERLHHWIDLNFGYKLSGKAAVKSKNV---CL--------TLV 566
            .|:|..||.|.:||:||||:.||..||.||||.||||..|.|||::.||   |.        .:.
 Frog  2284 KWSTSREDLIYQHRKALESEDVSLHLHEWIDLIFGYKQRGAAAVEALNVFYYCTYEGVVDLDAIA 2348

  Fly   567 DQHRNLSQRGIV--------QLFASAHPPRRYATPWFSRTAPRLSQLYA-SPAKRLAKSTENL-- 620
            |:....:..||:        |||...||||..|    ...|.|||::.. ||     ...|||
 Frog  2349 DETERKALEGIISNFGQTPCQLFKEPHPPRMTA----EHAARRLSRMDTYSP-----NVFENLAE 2404

  Fly   621 -----------------------QAES--ATGSSHLSLRLGDDGSSGSVHSSSASASASNFYAIT 660
                                   ||.|  ..||..:.:.:..:|..|:........:.||:::.|
 Frog  2405 LKSFFVEGMMEGVPLVLTVVPKTQAHSFMTQGSPDILVTVSSNGLLGTHGWLPYDKNISNYFSFT 2469

  Fly   661 NFIELPENYNPALLLHNLETLEAFYARTFPQQRASANPEEKMISSDLMFEQNSAEHSFTNQLFAS 725
            .        :|.  :.|::|           ||..:.|                        ||.
 Frog  2470 K--------DPT--VSNVKT-----------QRFLSGP------------------------FAL 2489

  Fly   726 GDELPPKS----------------KNLLR----EKRNCLQHLLNVRKERDLHVLGCLIIELFAMQ 770
            |.||..::                .|.||    .|...:.|:     .|.:.|:.||.::|..:.
 Frog  2490 GAELSSRTLVVSHDAKLLFSGGHWDNSLRVTSLSKGKVIGHI-----TRHIDVVSCLALDLCGIY 2549

  Fly   771 RLRPLLMGNGLTATFDSRLSACRTVAQLHRQELPKPVRRVVRLLLQLEQPGEEDQGLPQPPNPAQ 835
                |:.|        ||.:.|                    ::.|:.|.|....||  .|.|.|
 Frog  2550 ----LISG--------SRDTTC--------------------MIWQVLQQGGISCGL--SPKPVQ 2580

  Fly   836 LL 837
            :|
 Frog  2581 VL 2582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wdr81	NP_609535.1	Beach	345..588	CDD:100117	85/300 (28%)
		WD40	<1644..1877	CDD:225201
		WD40	1651..1876	CDD:295369
		WD40 repeat	1662..1705	CDD:293791
		WD40 repeat	1710..1744	CDD:293791
		WD40 repeat	1752..1788	CDD:293791
		WD40 repeat	1799..1836	CDD:293791
nbeal2	XP_031760024.1	DUF4704	895..1154	CDD:406270
		DUF4800	1673..1926	CDD:406460	41/268 (15%)
		PH_BEACH	1976..2076	CDD:275391	13/99 (13%)
		Beach	2098..2378	CDD:214982	85/300 (28%)
		WD40 repeat	2497..2533	CDD:293791	5/40 (13%)
		WD40	2503..2776	CDD:421866	24/119 (20%)
		WD40 repeat	2539..2584	CDD:293791	17/78 (22%)
		WD40 repeat	2636..2679	CDD:293791
		WD40 repeat	2684..2718	CDD:293791
		WD40 repeat	2724..2747	CDD:293791

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D101142at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010