DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment escl and C09G4.4

DIOPT Version :9

Sequence 1:	NP_001285857.1	Gene:	escl / 34611	FlyBaseID:	FBgn0032391	Length:	462	Species:	Drosophila melanogaster
Sequence 2:	NP_001379648.1	Gene:	C09G4.4 / 3565561	WormBaseID:	WBGene00044001	Length:	78	Species:	Caenorhabditis elegans

Alignment Length:	80	Identity:	21/80 - (26%)
Similarity:	28/80 - (35%)	Gaps:	32/80 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   229 SGSKD-----HSLRLW---NIQSD-------VCVAVFGGVEGHRDEVLSVD--FDLRGDRIMSSG 276
            :.|||     ||..|.   |:|||       |..:...|...|....:|.|  |:.||
Worm     5 TSSKDYSSPKHSFMLTVDSNLQSDKKKTFLNVQSSSSAGSTKHCQIPMSKDEYFETRG------- 62

  Fly   277 MDHSLKLWRLDKPDI 291
                    :||..|:
Worm    63 --------KLDSVDV 69

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
escl	NP_001285857.1	WD40	96..459	CDD:225201	21/80 (26%)
		WD40	107..352	CDD:295369	21/80 (26%)
		WD40 repeat	111..158	CDD:293791
		WD40 repeat	169..209	CDD:293791
		WD40 repeat	214..251	CDD:293791	11/36 (31%)
		WD40	253..>459	CDD:295369	9/41 (22%)
		WD40 repeat	261..323	CDD:293791	8/33 (24%)
		WD40 repeat	330..378	CDD:293791
		WD40 repeat	386..426	CDD:293791
		WD40 repeat	434..458	CDD:293791
C09G4.4	NP_001379648.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1034
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900