DRSC/TRiP Functional Genomics Resources

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Protein Alignment escl and Eed

DIOPT Version :8

Sequence 1:NP_001285857.1 Gene:escl / 34611 FlyBaseID:FBgn0032391 Length:462 Species:Drosophila melanogaster
Sequence 2:NP_001099748.1 Gene:Eed / 293104 RGDID:1309782 Length:441 Species:Rattus norvegicus

Alignment Length:476 Identity:245/477 (51%)
Similarity:315/477 (66%) Gaps:51/477 (11%)


  Fly     1 MTETNPSEISPPSEEPPAEDESTDHSPAEAVLSNNSSSVCNVVEPDDEHEVNSVDREDTASLFST 65
            |:|...|.....::.|.|:.:.         ||::.:|     .||    ::..:.:|..|:.|.
  Rat     1 MSEREVSTAPAGTDMPAAKKQK---------LSSDENS-----NPD----LSGDENDDAVSIESG 47

  Fly    66 TTT---TTRSKSPNTRKLNRLCRRIKAP--------KMVQPLYKYS----SHVREDHNHQIFGVQ 115
            |.|   .|.:.:||            ||        |......|||    :.::||||..:||||
  Rat    48 TNTERPDTPTNTPN------------APGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQ 100

  Fly   116 FNPFLDRGQPQVFATVGKDRVSIYECERSTGQESCEGIRLLQVYADPDTDESFYTCAWSYDSVTG 180
            ||.....|.|.||||||.:||::||| .|.|:     |||||.|.|.|.||:||||||:|||.|.
  Rat   101 FNWHSKEGDPLVFATVGSNRVTLYEC-HSQGE-----IRLLQSYVDADADENFYTCAWTYDSNTS 159

  Fly   181 DPVLAAAGYRGVIRIFNPVKHQCSKNYIGHGHAINELKFHPTRPQLLLSGSKDHSLRLWNIQSDV 245
            .|:||.||.||:|||.||:..||.|:|:|||:|||||||||..|.||||.||||:|||||||:|.
  Rat   160 HPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDT 224

  Fly   246 CVAVFGGVEGHRDEVLSVDFDLRGDRIMSSGMDHSLKLWRLDKPDIKEAIELSSGFSPNKNTGPF 310
            .||:|||||||||||||.|:||.|::|||.||||||||||::...:..||:.|..::|||...||
  Rat   225 LVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPF 289

  Fly   311 PTIKEHFPDFSTRDIHRNYVDCVQWFGDFVFSKSCENSIVCWKPGKLSESWHEIKPQESATTVLH 375
            .:.|.||||||||||||||||||:|.||.:.||||||:||||||||:.:...:|||.||..|:|.
  Rat   290 ISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILG 354

  Fly   376 HFDYKMCEIWFVRFAFNAWQKILALGNQLGTTFVWELDCNDPNLTKCSQLVHPKSNSTIRQTSFS 440
            .|||..|:||::||:.:.|||:||||||:|..:||:|:..||:..||:.|.|.|..:.|||||||
  Rat   355 RFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFS 419

  Fly   441 KDGSILVCVCDDSTVWRWDRV 461
            :|.|||:.||||:::|||||:
  Rat   420 RDSSILIAVCDDASIWRWDRL 440

Known Domains:


GeneSequenceDomainRegion External IDIdentity
esclNP_001285857.1 WD40 96..459 CDD:225201 222/367 (60%)
WD40 107..352 CDD:295369 159/245 (65%)
WD40 repeat 111..158 CDD:293791 26/47 (55%)
WD40 repeat 169..209 CDD:293791 25/40 (63%)
WD40 repeat 214..251 CDD:293791 28/37 (76%)
WD40 253..>459 CDD:295369 124/206 (60%)
WD40 repeat 261..323 CDD:293791 35/62 (56%)
WD40 repeat 330..378 CDD:293791 29/48 (60%)
WD40 repeat 386..426 CDD:293791 20/40 (50%)
WD40 repeat 434..458 CDD:293791 17/24 (71%)
EedNP_001099748.1 WD40 repeat 96..140 CDD:293791 27/50 (54%)
WD40 repeat 148..188 CDD:293791 25/40 (63%)
WD40 150..438 CDD:356469 181/288 (63%)
WD40 repeat 193..230 CDD:293791 28/37 (76%)
WD40 repeat 240..302 CDD:293791 35/62 (56%)
WD40 repeat 309..357 CDD:293791 29/48 (60%)
WD40 repeat 365..405 CDD:293791 20/40 (50%)
WD40 repeat 413..437 CDD:293791 17/24 (71%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 C198455877
eggNOG 1 0.900 E1_KOG1034
Hieranoid 1 1.000
Homologene 1 1.000 H2814
Inparanoid 1 1.050 488 1.000 Inparanoid score I1344
OMA 1 1.010
OrthoDB 1 1.010 D1191277at2759
OrthoFinder 1 1.000 FOG0005209
OrthoInspector 1 1.000 T618015
orthoMCL 1 0.900 OOG5_130364
Panther 1 1.100 LDO PTHR10253
Phylome 1 0.910 0.667 Consistency score
TreeFam 1 0.960
1312.770

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