Protein Alignment CG6686 and Sart1

DIOPT Version :10

• Sequence 1: NP_723700.1
• Gene: CG6686 / 34608
• FlyBaseID: FBgn0032388
• Length: 970
• Species: Drosophila melanogaster
• Sequence 2: NP_058578.3
• Gene: Sart1 / 20227
• MGIID: 1309453
• Length: 806
• Species: Mus musculus
• Alignment Length: 846
• Identity: 327/846 - (38%)
• Similarity: 459/846 - (54%)
• Gaps: 157/846 - (18%)

  Fly   199 TAPPPPQISKHAEYESR---------REREIERERDARKRSGRERERERNRE----RSRSQSPAS 250
            |...||:..:|.:::.|         ..|:..|||.:.:.|||.......|.    |.|||:..|
Mouse    25 TTEQPPRHREHKKHKHRSSGGGSSGGERRKRSRERGSERGSGRRGAEAEARSGAHGRERSQAEPS 89

  Fly   251 SSRKPATKEREPSSRSFSPIPENGAGDVLSITETNKLRAKLGLKPLEVDSGPSKAGPPPGSSSQG 315
            ..|....|..:....:.|....:|....|||.||||||||||||||||::...:||
Mouse    90 ERRVKREKRDDGYEAAASSKASSGDASSLSIEETNKLRAKLGLKPLEVNAVKKEAG--------- 145

  Fly   316 EIKKPHGEADLSSYKDEWGEFLHKPADNLKEKREAEKLREKLKQRKEKRFLEERLARIKTLGESD 380
             .|:....||:.               |....|:.|:|||||...||||.|.::|.:||||||.|
Mouse   146 -TKEEPVAADVI---------------NPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDD 194

  Fly   381 EETDNVSKWVDKNKRVVNEREEAMRKAKELEELDEAFGVSEILEQEKTKARQRAYGDSNLKGLRV 445
            ...|:.:.|:::::::..|::.|.::||.|||:|:.||||.::|:|..:.||..|...:|:||.|
Mouse   195 PWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFEQRRQDLYSARDLQGLTV 259

  Fly   446 DHDMDDFGEGRTVILTLKDQDVLNEEEGDTLVNVNMVDEERYKKNVANKKQNP--LSYGYNVYEE 508
            :|.:|.|.||.||:|||||:.||.:.| |.||||||||:||..|||..:|:.|  |.|   ..:|
Mouse   260 EHAIDSFREGETVVLTLKDKGVLQDGE-DVLVNVNMVDKERADKNVELRKKKPDYLPY---AEDE 320

  Fly   509 QYDELGNPIERSVLEKYDDEMEGQPKKRKNFVIGENMDEEREHRRKLLEIKTKLAGKRL--ETLE 571
            ..|:|.....||:|.|||:|:||:.........|...|..||  |:|.||:|||   ||  ::|.
Mouse   321 SVDDLAQQKPRSILAKYDEELEGERPHSFRLEQGGMADGLRE--RELEEIRTKL---RLQAQSLS 380

  Fly   572 DTNLQLASDTYSAEELAKFKKPKKKVKKLRQK-----LKAEDLAPLAMGEASGSSDFGSR---GG 628
            ....:|||:..|.||:..|||.|::|||:|:|     ::|:||.||  |:.:...|||||   .|
Mouse   381 SVGPRLASEYLSPEEMVTFKKTKRRVKKIRKKEKEVIMRADDLLPL--GDQTQDGDFGSRLRGRG 443

  Fly   629 RYR----DHEDAEMEEFKP--------QIKVE--------------------VEDD----DLERV 657
            |.|    :.|..|.||..|        ..:||                    :|:|    :|::.
Mouse   444 RRRVPEVEEEALEDEEKDPVAQPPPSDDTRVENMDISDEEDGGALPPGSPEGLEEDEAELELQKQ 508

  Fly   658 LAKARKLKQKE-------------NIIKKPLPVDFESIQR----EIKPEHVEDTASGVVLTGVDG 705
            |.|.|:|:|.:             .|:||     .||.||    |..||.             .|
Mouse   509 LEKGRRLRQLQQLQQLRDSGEKVLEIVKK-----LESRQRGWEEEEDPER-------------KG 555

  Fly   706 NIVLNATAEFCRTLGDIPTYGMAGNRNEDSNDMMDFDKTEQPEEHMETHTD-EPALSHGTWNSVN 769
            .||.|||:|||||||:|||||:|||| |:..::|||::.|:...:..:.:| |..:.   |::||
Mouse   556 TIVFNATSEFCRTLGEIPTYGLAGNR-EEQEELMDFERDEERSANGGSESDGEENIG---WSTVN 616

  Fly   770 PDEVMQPADLDNLGEDLEDRAILDEEPDVGAGVANALRLALSKGYLEKEEKNRPSNTKMAHLQAK 834
            .||..|..|.     ......||||||.|..|:|.||.|..:||.||...:      |:|.::|.
Mouse   617 LDEEKQHQDF-----SASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQ------KVARVKAP 670

  Fly   835 N-------YSIEDKAAGEDEKVGRRDRFHFGPITDFKDKETFKPNVKLDYIDDNGRILNLKEAFR 892
            |       |.||||.| .|:|..||:.:. |...|||:|:.:||:||::|:|:.||.|..|||||
Mouse   671 NKSLPSAVYCIEDKMA-IDDKYSRREEYR-GFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFR 733

  Fly   893 YLSHKFHGKGPGKNKIEKRLKKMEQDGLMKTMSSTDTPLGTLTMLQQKQKETKTAYVVLSGNNKN 957
            .|||:|||||.||.|.|:|:||::::.|:|.|||:||||||:.:||:|||..||.|:||||:.|:
Mouse   734 QLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQKTPYIVLSGSGKS 798

  Fly   958 V 958
            :
Mouse   799 M 799

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6686	NP_723700.1	HIND	279..298	CDD:466011	17/18 (94%)
		SART-1	351..918	CDD:460888	255/639 (40%)
Sart1	NP_058578.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..121		24/95 (25%)
		HIND	118..137	CDD:466011	17/18 (94%)
		SART-1	165..759	CDD:460888	255/639 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	418..504		23/87 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	578..610		11/32 (34%)