Protein Alignment esc and eed

DIOPT Version :10

• Sequence 1: NP_477431.1
• Gene: esc / 34595
• FlyBaseID: FBgn0000588
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: NP_001017325.1
• Gene: eed / 550079
• XenbaseID: XB-GENE-491480
• Length: 438
• Species: Xenopus tropicalis
• Alignment Length: 422
• Identity: 218/422 - (51%)
• Similarity: 295/422 - (69%)
• Gaps: 8/422 - (1%)

  Fly     1 MSSDKVKNGNEPEESEESCGDESASYTTNSTTSRSKSPSSSTRSKRR---GRRSTKSKPKSRAAY 62
            :|||:..|   ||.|.:. .|::.|..:.:.|.|..:|:::..:..|   |:...||| |.:.::
 Frog    20 LSSDENSN---PELSGDE-NDDTVSIESGTNTERPDTPTNAANAPGRKGWGKGKWKSK-KCKYSF 79

  Fly    63 KYDTHVKENHGANIFGVAFNTLLGKDEPQVFATAGSNRVTVYECPRQGGMQLLHCYADPDPDEVF 127
            |....:||:|...:|||.||....:.:|.||||.||||||:|||..||.::||..|.|.|.||.|
 Frog    80 KCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHPQGEIRLLQSYVDADADENF 144

  Fly   128 YTCAWSYDLKTSSPLLAAAGYRGVIRVIDVEQNEAVGNYIGHGQAINELKFHPHKLQLLLSGSKD 192
            |||||:||..||.||||.||.||:||:|:....:.:.:|:|||.|||||||||....||||.|||
 Frog   145 YTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKD 209

  Fly   193 HAIRLWNIQSHVCIAILGGVEGHRDEVLSIDFNMRGDRIVSSGMDHSLKLWCLNTPEFHHKIELS 257
            ||:||||||:...:||.||||||||||||.|:::.|::|:|.|||||||||.:|:......|..|
 Frog   210 HALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSLRMKTAIRES 274

  Fly   258 NTFSQEKSTLPFPTVTKHFPDFSTRDIHRNYVDCVQWFGNFVLSKSCENAIVCWKPGQLHQSFEQ 322
            ..::..|:..||.:...||||||||||||||||||:|.|:.:|||||||||||||||::....::
 Frog   275 YEYNPNKTNRPFVSQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDK 339

  Fly   323 VKPSDSSCTIIAEFEYDECEIWFVRFGFNPWQKVIALGNQQGKVYVWELDPSDPEGAHMTTLHNS 387
            :|.|:|:.||:..|:|.:|:||::||..:.|||::|||||.||:|||:|:..||..|..|||...
 Frog   340 IKASESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTYP 404

  Fly   388 RSVATVRQIAFSRDASVLVYVCDDATVWRWNR 419
            :..:.:||.:||||:|:||.||||||:|||:|
 Frog   405 KCASAIRQTSFSRDSSILVAVCDDATIWRWDR 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
esc	NP_477431.1	WD40	72..420	CDD:441893	197/348 (57%)
		WD40 repeat	76..122	CDD:293791	25/45 (56%)
		WD40 repeat	128..168	CDD:293791	21/39 (54%)
		WD40 repeat	173..210	CDD:293791	25/36 (69%)
		WD40 repeat	220..282	CDD:293791	27/61 (44%)
		WD40 repeat	289..337	CDD:293791	26/47 (55%)
		WD40 repeat	345..386	CDD:293791	22/40 (55%)
		WD40 repeat	393..417	CDD:293791	16/23 (70%)
eed	NP_001017325.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..70		14/53 (26%)
		WD 1	88..131		22/42 (52%)
		WD40 repeat	93..137	CDD:293791	24/43 (56%)
		WD40	<106..436	CDD:441893	190/329 (58%)
		WD 2	139..182		24/42 (57%)
		WD40 repeat	145..185	CDD:293791	21/39 (54%)
		WD 3	185..225		27/39 (69%)
		WD40 repeat	190..227	CDD:293791	25/36 (69%)
		WD 4	231..270		22/38 (58%)
		WD40 repeat	237..299	CDD:293791	27/61 (44%)
		WD 5	301..338		26/36 (72%)
		WD40 repeat	306..354	CDD:293791	26/47 (55%)
		WD 6	356..396		21/39 (54%)
		WD40 repeat	362..402	CDD:293791	21/39 (54%)
		WD 7	405..438		19/32 (59%)
		WD40 repeat	410..434	CDD:293791	16/23 (70%)