Protein Alignment Pde1c and pde2a

DIOPT Version :10

• Sequence 1: NP_001137817.1
• Gene: Pde1c / 34594
• FlyBaseID: FBgn0264815
• Length: 1173
• Species: Drosophila melanogaster
• Sequence 2: XP_031751996.1
• Gene: pde2a / 780063
• XenbaseID: XB-GENE-5945995
• Length: 964
• Species: Xenopus tropicalis
• Alignment Length: 317
• Identity: 95/317 - (29%)
• Similarity: 158/317 - (49%)
• Gaps: 30/317 - (9%)

  Fly   772 LFNRYGSIHKFKIAPGILEAFLHRVEEGYCRYRN-PYHNNLHAVDVMQTIHYCLC---NTGLMNW 832
            :|...|.::.:||....|..|...|::|   ||: ||||.:||..|.   |:|..   |..|:|:
 Frog   638 MFEDMGFVNNYKIDRTTLIRFCLMVKKG---YRDPPYHNWMHAFSVS---HFCYLLFKNLELVNY 696

  Fly   833 LTDLEIFASLLAALLHDYEHTGTTNNFHVMSGSETALLY-NDRAVLENHHASASFRLLREDEYNI 896
            |..:||||..::.|.||.:|.||.|:|.|.|.|..|.|| ::.:|:|.||.:.:..:|.....||
 Frog   697 LEYIEIFALFVSCLCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNSQGCNI 761

  Fly   897 LSHLSREEFRELRGLVIEMVLGTDMTNHFQQMKAMRQLLTLQEATIDKQK------VLSLVLHCC 955
            |...||::::.:..|:.:::|.||:.:|   ::..::|..:.:...|.|.      ::.|::...
 Frog   762 LEQFSRKDYQRMLDLMRDIILATDLAHH---LRIFKELTRMSQDGFDPQNKHHHYLLICLLMTSS 823

  Fly   956 DISHPAKQWGVHHRWTMLLLEEFFRQGDLEKELGLPFSPLCDRNNTLVAESQICFIDFIVEPSMG 1020
            |:|...|.|....:...|:.:|||.||||||.:|...|.:.||....:.|.||.|::.|..|...
 Frog   824 DLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPSEMMDREKAYIPELQISFMEHIAMPIYN 888

  Fly  1021 VMSDML--ELILAPIAPMNKSKPATLVEHETTANSTTNSAIVIPNSGITPSMDKPRD 1075
            ::.|:.  ...|......|:.| .|.|.|:.|...       :|::.....:|:..|
 Frog   889 LLKDLFPRSAELYERVATNREK-WTRVSHKFTIRG-------LPSNNSLDFLDEEYD 937

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pde1c	NP_001137817.1	PDEase_I_N	662..722	CDD:462497
		PDEase_I	807..1027	CDD:459723	74/231 (32%)
pde2a	XP_031751996.1	GAF	255..401	CDD:214500
		GAF	423..574	CDD:214500
		PDEase_I	671..904	CDD:459723	75/238 (32%)