Protein Alignment CG6488 and Cog8

DIOPT Version :8

• Sequence 1: NP_609503.2
• Gene: CG6488 / 34571
• FlyBaseID: FBgn0032361
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: NP_001099652.1
• Gene: Cog8 / 291990
• RGDID: 1307074
• Length: 634
• Species: Rattus norvegicus
• Alignment Length: 549
• Identity: 248/550 (45%)
• Similarity: 344/550 (63%)
• Gaps: 13/550 (2%)

  Fly     8 DLENERVLKLIFPDGVPD-NLRGNPELDNYLAKLGTCKVEQLKKEQTRLAEEARTILEQTQDLAI 71
            ::|:|.:|..:|.|..|: ..|..|::..||.:|....:::|::|..|||||...:|:||:|||.
  Rat    26 EVEDEGLLASLFRDRFPEAQWREKPDVGRYLRELSGSGLDRLRREPERLAEERAQLLQQTRDLAF 90

  Fly    72 SNYRTFITTAENSRSIFSEFLRSEQQLDTLVSKLPDLSVQCERFLQDSAELNEQRRLNSITLQKN 136
            :||:|||..||.:..|...|...|..|..|:.:||.....|..|::::.|::..||:|::||.::
  Rat    91 ANYKTFIRGAECTERIHRLFGDVEASLGHLLDRLPSFQQSCRNFVKEAEEISSNRRMNTLTLNRH 155

  Fly   137 AQLLEVLELPQLMERCIREGRYEEALELAAYATRLGQHQGHIPVVTSIVRSVEALWHNMLVQLVA 201
            .::||:||:||||:.|:|...||||||||||..||.:....|||:..||..|......||.||:.
  Rat   156 TEILEILEIPQLMDTCVRNSYYEEALELAAYVRRLERKYSSIPVIQGIVNEVRQSMQLMLSQLIQ 220

  Fly   202 QLRTDLQLPKCLQIVGYLRRMQAFGDNELRLKFLQARDAWLTSCLEAIPTADAQQHLSKTIEITR 266
            ||||.:|||.||:::||||||..|.:.|||:||||||||||.|.|.|||..|...|::||||..|
  Rat   221 QLRTSIQLPACLRVIGYLRRMDVFTEAELRVKFLQARDAWLRSILTAIPNDDPYFHITKTIEACR 285

  Fly   267 INLFNIITQYRAIFPEDEGTLKTQSSLRPLQG-VSCNGDRLFQAWLHNKISDFLQTLERDLQLGV 330
            ::||:||||||||| .||..|     |.|..| .:.|...:|..|:..|||.|||.||.||..|:
  Rat   286 VHLFDIITQYRAIF-SDEDPL-----LPPAMGQYTVNEGAIFHGWVLQKISQFLQVLETDLYRGI 344

  Fly   331 GS-VETVLGQCMYFGLSFSRVGADFRALMAPIFVGVIRRRFESSVEQVDEQFERELERFTLINKV 394
            |. ::::|||||||||||||||||||..:||:|..|....|:.:||:..|:|:.|:..:|||:..
  Rat   345 GGRLDSLLGQCMYFGLSFSRVGADFRGQLAPVFQRVAINTFQKAVEEAVEKFQDEMTSYTLISAA 409

  Fly   395 AL--HSHARKQVDPEQE-SYAPPEALLDFYPLAALCNGYLSALNELRLCAPLALATDVTRCLQHS 456
            |:  .|:....|...|. :..||..||||.|||...|..|.|.|:||||.|:|||.|||..|:.:
  Rat   410 AILGSSNMPAAVPATQPGTLQPPMVLLDFPPLACFLNNILVAFNDLRLCCPVALAQDVTGALEDA 474

  Fly   457 LQQAAQRVLAFYRQEQQAFAGSEREAFVRLCSCLAYDLVPYIQRCIHGVFPPQSLTVHLGISLLQ 521
            |.:..:.:|||:|.|:..|:..|.|.||:.|:....|||||:.||:..:|||..:...||||..|
  Rat   475 LMKVTKTILAFHRAEEAVFSSGEHEIFVQFCTAFLEDLVPYLNRCLQVLFPPAQIAQTLGISPTQ 539

  Fly   522 LEQQ-QLTYLQQTRILEPLKHLLPTKALV 549
            |.:. .|.::..:.|.|||..:||.:..|
  Rat   540 LSKHGNLGHVNISAIQEPLAFILPKREAV 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6488	NP_609503.2	Dor1	37..379	CDD:252394	168/344 (49%)
Cog8	NP_001099652.1	Dor1	56..394	CDD:252394	168/344 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C192712990
eggNOG	1	0.900				E1_KOG2069
Hieranoid	1	1.000
Homologene	1	1.000				H13018
Inparanoid	1	1.050	449	1.000	Inparanoid score	I1539
OMA	1	1.010
OrthoDB	1	1.010				D1531483at2759
OrthoFinder	1	1.000				FOG0004180
OrthoInspector	1	1.000				T1087960
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			LDO	PTHR21311
Phylome	0	0.000	Not matched by this tool.
TreeFam	1	0.960
	11	10.960