Protein Alignment Cog8 and cog8

DIOPT Version :9

• Sequence 1: NP_609503.2
• Gene: Cog8 / 34571
• FlyBaseID: FBgn0287204
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: XP_002937620.2
• Gene: cog8 / 100495068
• XenbaseID: XB-GENE-955478
• Length: 605
• Species: Xenopus tropicalis
• Alignment Length: 545
• Identity: 231/545 - (42%)
• Similarity: 341/545 - (62%)
• Gaps: 8/545 - (1%)

  Fly     7 MDLENERVLKLIFPDGVPDNLRGNPELDNYLAKLGTCKVEQLKKEQTRLAEEARTILEQTQDLAI 71
            ||:|:|.:|..:|....|::.|.:|:..:||.:|.:..:::|::|..||::|...||:||:|||.
 Frog    11 MDVEDEGLLASVFRASFPESWRDSPDFASYLLELSSFGLDKLRREPERLSDERSQILQQTRDLAF 75

  Fly    72 SNYRTFITTAENSRSIFSEFLRSEQQLDTLVSKLPDLSVQCERFLQDSAELNEQRRLNSITLQKN 136
            |||:|||.|||.:..|:.:|.:.|..:..|::|||.....|..|::.:.|::..||:|::||.::
 Frog    76 SNYKTFIRTAECTELIYRDFGQVEGSVSHLLNKLPSFQESCRNFVKQAEEISSSRRMNTLTLNRH 140

  Fly   137 AQLLEVLELPQLMERCIREGRYEEALELAAYATRLGQHQGHIPVVTSIVRSVEALWHNMLVQLVA 201
            .::||:||:||||:.|:|.|.||||||||||..||.:....:||:..||..|......||.||:.
 Frog   141 TEILEILEIPQLMDTCVRNGYYEEALELAAYVRRLEKKHSSVPVIQGIVNEVRQSAQLMLNQLLQ 205

  Fly   202 QLRTDLQLPKCLQIVGYLRRMQAFGDNELRLKFLQARDAWLTSCLEAIPTADAQQHLSKTIEITR 266
            |||:::|||.||:::||||||..|.:.|||:|||||||:||.|...:||..|...||:||||..|
 Frog   206 QLRSNIQLPACLRVIGYLRRMDVFTEAELRIKFLQARDSWLRSLQNSIPNDDPYFHLTKTIESCR 270

  Fly   267 INLFNIITQYRAIFPEDEGTLKTQSSLRPLQGVSCNGDRLFQAWLHNKISDFLQTLERDLQLGVG 331
            :|||::||||||||.:::..|....   |...:..:...:|..|:..|:::|||.|:.|||.|||
 Frog   271 VNLFDVITQYRAIFSDEDPLLLPPP---PTGTLPISEGAIFHGWVLQKVTEFLQVLQNDLQRGVG 332

  Fly   332 S-VETVLGQCMYFGLSFSRVGADFRALMAPIFVGVIRRRFESSVEQVDEQFERELERFTLIN-KV 394
            . ::::|||||||||||||||.|||..:.|||..|....|..:|.:..|:|:.|:..:|||: ..
 Frog   333 GRLDSLLGQCMYFGLSFSRVGVDFRGQLPPIFQRVAAETFAKAVHEAVEKFQEEMNMYTLISAPT 397

  Fly   395 ALHSHARKQVDPEQE--SYAPPEALLDFYPLAALCNGYLSALNELRLCAPLALATDVTRCLQHSL 457
            .|.|.......|..:  :..||..||||.|||...|..|.|.|:||||.|:||...||..||.:|
 Frog   398 VLGSTITPVPTPTAQPGTLQPPMVLLDFPPLACFLNNILVAFNDLRLCCPVALTEAVTTTLQDAL 462

  Fly   458 QQAAQRVLAFYRQEQQAFAGSEREAFVRLCSCLAYDLVPYIQRCIHGVFPPQSLTVHLGISLLQL 522
            ::..:.:|.|.|.|:.||:..|||.|::.|:....||.|::.||:..:|||......||::...|
 Frog   463 EKVVKTILTFQRAEEAAFSMQERELFIQFCTVFLEDLTPFLNRCLQVLFPPAQRAQILGVAPAHL 527

  Fly   523 EQQ-QLTYLQQTRILEPLKHLLPTK 546
            .:. .|..:..|.:.|.|:.:||.|
 Frog   528 SRYGNLCSIDVTVLQEALEGILPQK 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cog8	NP_609503.2	Dor1	37..379	CDD:252394	158/342 (46%)
cog8	XP_002937620.2	Dor1	41..381	CDD:252394	158/342 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	312	1.000	Domainoid score	I1290
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H13018
Inparanoid	1	1.050	438	1.000	Inparanoid score	I1639
OMA	1	1.010	-	-		QHG53892
OrthoDB	1	1.010	-	-		D1531483at2759
OrthoFinder	1	1.000	-	-		FOG0005159
OrthoInspector	1	1.000	-	-		oto105558
Panther	1	1.100	-	-	LDO	PTHR21311
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R223
SonicParanoid	1	1.000	-	-		X4192
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110