DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment salr and Sall1

DIOPT Version :10

Sequence 1:NP_523548.1 Gene:salr / 34568 FlyBaseID:FBgn0000287 Length:1267 Species:Drosophila melanogaster
Sequence 2:NP_067365.2 Gene:Sall1 / 58198 MGIID:1889585 Length:1323 Species:Mus musculus


Alignment Length:1362 Identity:395/1362 - (29%)
Similarity:557/1362 - (40%) Gaps:321/1362 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 DRDRDRDRDRDRERDRDTLLAKELDADSNNNGTEPQMEAEAVPESDTERETAEERGEE------- 84
            |:.:|.....|:|...|....|.||       .|..||.| ||.:.|...|....|..       
Mouse    96 DQMKDAANKADQEDCSDLSEPKGLD-------REESMEVE-VPVATTTTTTTGGSGGSGGSTLSG 152

  Fly    85 ----QEPE-NSNEALDLSLISSGGRESLPGSG-------------HVSLEALQHTKVAVAQFAAT 131
                ..|. :|..:...|.|::    |||..|             :|.:|.||.||||||||:..
Mouse   153 VTNITTPSCHSGSSTGTSAITT----SLPQLGDLTTLGNFSVINSNVIIENLQSTKVAVAQFSQE 213

  Fly   132 AMAGNHQSADL--AMVQSTIFNVQRQHLMQLQLIQ------------------------------ 164
            |..|......|  :.:...:..:|:|.:.|||||:                              
Mouse   214 ARCGGASGGKLLISTLMEQLLALQQQQIHQLQLIEQIRHQILLLASQSADLPAAPSIPSQGTLRT 278

  Fly   165 ----------HLQSQLKRAEAAALGRHSHSDEE-----EEEPEPE-PEPKK-----QPTNGLKEE 208
                      ||..||  |.||.|.:...|...     ::.|..: |:...     .|:.|....
Mouse   279 SANPLTTLSSHLSQQL--AVAAGLAQSLASQSANISGVKQLPHVQLPQSSSGTSIVPPSGGTSPN 341

  Fly   209 LELEQG--PESEQDQESRREENSKTDKRGTEDRKAEPEGYQSMMCDISSSL------ASSIITNH 265
            :.:...  |....::.:.....|...........:......|::...|:.|      |:::.   
Mouse   342 MSIVTAAVPTPSSEKVASNAGASHVSSPAVSASSSPAFAISSLLSPASNPLLPQPTPANAVF--- 403

  Fly   266 DPPPAPNEPNCLEMLQRRTEEVLDSASQSLHAAQMQEEYSEYASKEAQSRGE--IFKHRCKYCGK 328
             |.|.||.....|          |..|.|..|.|.:.:.....:.||:|..:  .|||:|::|.|
Mouse   404 -PTPLPNIATTAE----------DLNSLSALAQQRKSKPPNVTAFEAKSTSDEAFFKHKCRFCAK 457

  Fly   329 IFGSYSALQIHLRSHTGERPFVCNVCGSKFTTKGNLKVHYQRHTQIFPPMLLPPGVAP----NVG 389
            :|||.||||||||||||||||.||:||::|:||||||||:|||.:.:|.:.:.|...|    ||.
Mouse   458 VFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEHLDNVP 522

  Fly   390 HSGQGQVQGEQYPIRLPFAPPVAPVGQEQHQNQVEEPEEIRQEIPVPQAEDLSKPMVKEKEKSHS 454
            .|     .|..|.:.:   ||..||........|.........:|:|.......|.:|.:|.:..
Mouse   523 TS-----TGIPYGMSI---PPEKPVTSWLDTKPVLPTLTTSVGLPLPPTLPSLTPFIKTEEPAPI 579

  Fly   455 PVER-VKTPK-EVKTDAALPS------SEKPEKEISKPVVTSSRRNGSVRKRQTSAV-------- 503
            |:.. ..:|: .||:|:..|.      |..|| |:....|......|......:|||        
Mouse   580 PISHSAASPQGSVKSDSGAPDLATRNPSGVPE-EVEGSAVPPFGGKGEESNMASSAVPTAGNSTL 643

  Fly   504 -SPPQEDRERDLVEHLHIAKLVRRSSASRESQPAEYSLAQMERIIDKSWEDLIEIDKTSETSKLQ 567
             ||..:...........:..|:      .|...|::...           .|::..:.|||||||
Mouse   644 NSPVADGGPGGTTFTNPLLPLM------SEQFKAKFPFG-----------GLLDSAQASETSKLQ 691

  Fly   568 QLVDNIENKLTDPNQCIFCQKVMSCRSSLQMHIRTHTGERPFRCKICGRAFATKGNLKAHMSIHK 632
            |||:||:.|.||||:||.|.:|:||:|:|:||.|||||||||:||||||||.||||||.|.|:|:
Mouse   692 QLVENIDKKATDPNECIICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHYSVHR 756

  Fly   633 IKPPMRSQFKCPVCHQKFSNGIILQQHIRIHTMDDGSGGQ----GAPAANPGEAERLGIEDQNSN 693
            ..||:|.|..||:|.:||:|.::||||||:|     .|||    ..|...|          ::..
Mouse   757 AMPPLRVQHSCPICQKKFTNAVVLQQHIRMH-----MGGQIPNTPVPDNYP----------ESME 806

  Fly   694 KSLGTSDTLDFSTTISDHSGQRSESSQGGDFDEFMTMDSTDDSRDNSSAATATPHPLERERDREK 758
            ...|:.|..:|. .:.:.|.:..|....|...:  |..|.|.|:|:.|   ::|.|||.......
Mouse   807 SDTGSFDEKNFD-DLDNFSDENMEECPEGSIPD--TPKSADASQDSLS---SSPLPLEMSSIAAL 865

  Fly   759 ERERRIPNDCSDE------RSHSNPDLTG------GRSESGEMPAMDLSSPS------------- 798
            |.:.::.|....|      :|..|..:.|      ..|..|:|.:....||:             
Mouse   866 ENQMKMINAGLAEQLQASLKSVENGSMEGDVLTNDSSSVGGDMESQSAGSPAISESTSSMQALSP 930

  Fly   799 SNSGRIF--ATGLAN--GAAGGGSGNGGLPMLGMPMPPN---LLLMAAAREEM---HALGHAHAK 853
            |||.:.|  :.|:..  ...|.|....||    .|.|.|   |.|.::..|::   .:||     
Mouse   931 SNSTQEFHKSPGMEEKPQRVGPGEFANGL----SPTPVNGGALDLTSSHAEKIIKEDSLG----- 986

  Fly   854 FPLLPFGPLG-FMGLHPPPNVCNLCFKMLPSLAALESHLQSEHAKEPATGHAQRP-QCSDAGSPY 916
             .|.||...| |..     ..|::|.|.....:||:.|.:| |.||       || .|:.....:
Mouse   987 -ILFPFRDRGKFKN-----TACDICGKTFACQSALDIHYRS-HTKE-------RPFICTVCNRGF 1037

  Fly   917 GAKLTLNPNLFA---KKPPSSSSSSSGEKLPESSNPPFPAENPPATPIKEDPDQEQLMVEEGASA 978
            ..|..|..::..   :..||.....|....|..::...|| |..::.||.:.:            
Mouse  1038 STKGNLKQHMLTHQMRDLPSQLFEPSSNLGPNQNSAVIPA-NSLSSLIKTEVN------------ 1089

  Fly   979 GEGSGTGATSNYPQEAGDAEQSLMKMQLHAHRFPASPLDFQQALMSAGPPTSSLDPPVNNKHFCH 1043
                  |.....||::.||..|      |..:.|.|.......|:.|.|..:.      .:|:|:
Mouse  1090 ------GFVHVSPQDSKDAPTS------HVPQGPLSSSATSPVLLPALPRRTP------KQHYCN 1136

  Fly  1044 VCRRNFSSSSALQIHMRTHTGDKPFQCNVCQKAFTTKGNLKVHMGTHMWTNPTSRRGRRMSLELP 1108
            .|.:.||||||||||.|||||:|||.|.:|.:|||||||||||||||||.:..:|||||:|::.|
Mouse  1137 TCGKTFSSSSALQIHERTHTGEKPFACTICGRAFTTKGNLKVHMGTHMWNSTPARRGRRLSVDGP 1201

  Fly  1109 M-----RP-----------GPNSGQGHPGSSAEQEFMQRRPELFFPYLPPFFNGLPPKPGELSPG 1157
            |     .|           ...||.|.|.|...|            |.....|||..|..|:|..
Mouse  1202 MTFLGGNPVKFPEMFQKDLAARSGSGDPSSFWNQ------------YTAALSNGLAMKANEISVI 1254

  Fly  1158 AFPNIPPPPFANGGKYPYP-PGLLGFPGFLAQHPYILERRSSSKSPTPEPAQSPALREEEGS 1218
            ....|||.|.:.|.....| .||.|          .:|:..:|:...|..........|.|:
Mouse  1255 QNGGIPPIPGSLGSGSSSPISGLTG----------NVEKLGNSEPSAPLAGLEKMASSENGT 1306

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
salrNP_523548.1 SUF4-like 320..>371 CDD:411020 38/50 (76%)
C2H2 Zn finger 323..344 CDD:411020 15/20 (75%)
C2H2 Zn finger 323..343 CDD:275368 14/19 (74%)
C2H2 Zn finger 351..371 CDD:411020 14/19 (74%)
C2H2 Zn finger 351..371 CDD:275368 14/19 (74%)
SUF4-like 583..>636 CDD:411020 36/52 (69%)
C2H2 Zn finger 583..604 CDD:411020 12/20 (60%)
C2H2 Zn finger 583..603 CDD:275368 11/19 (58%)
zf-H2C2_2 595..620 CDD:463886 20/24 (83%)
C2H2 Zn finger 611..631 CDD:411020 16/19 (84%)
C2H2 Zn finger 611..631 CDD:275368 16/19 (84%)
C2H2 Zn finger 643..663 CDD:275368 12/19 (63%)
lambda-1 1013..>1061 CDD:212564 17/47 (36%)
SUF4-like 1039..>1087 CDD:411020 33/47 (70%)
C2H2 Zn finger 1042..1063 CDD:411020 14/20 (70%)
C2H2 Zn finger 1042..1062 CDD:275368 13/19 (68%)
C2H2 Zn finger 1070..1090 CDD:275368 15/19 (79%)
C2H2 Zn finger 1070..1087 CDD:411020 12/16 (75%)
Sall1NP_067365.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..41
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 78..128 11/38 (29%)
SUF4-like 449..536 CDD:411020 49/94 (52%)
C2H2 Zn finger 452..473 CDD:411020 15/20 (75%)
C2H2 Zn finger 452..472 CDD:275368 14/19 (74%)
C2H2 Zn finger 480..500 CDD:411020 14/19 (74%)
C2H2 Zn finger 480..500 CDD:275368 14/19 (74%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 578..659 17/81 (21%)
COG5048 700..1168 CDD:227381 171/542 (32%)
C2H2 Zn finger 707..727 CDD:275368 11/19 (58%)
zf-H2C2_2 719..744 CDD:463886 20/24 (83%)
C2H2 Zn finger 735..755 CDD:275368 16/19 (84%)
zf-C2H2 765..787 CDD:395048 12/21 (57%)
C2H2 Zn finger 767..787 CDD:275368 12/19 (63%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 789..855 17/81 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 891..961 15/73 (21%)
C2H2 Zn finger 1002..1022 CDD:275370 7/20 (35%)
SUF4-like 1005..>1049 CDD:411020 14/51 (27%)
C2H2 Zn finger 1005..1023 CDD:411020 6/18 (33%)
zf-C2H2 1028..1050 CDD:395048 3/21 (14%)
C2H2 Zn finger 1030..1050 CDD:275370 3/19 (16%)
C2H2 Zn finger 1030..1049 CDD:411020 3/18 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1094..1119 8/30 (27%)
SUF4-like 1133..>1180 CDD:411020 33/46 (72%)
C2H2 Zn finger 1135..1156 CDD:411020 14/20 (70%)
C2H2 Zn finger 1135..1155 CDD:275368 13/19 (68%)
C2H2 Zn finger 1163..1183 CDD:275368 15/19 (79%)
C2H2 Zn finger 1163..1180 CDD:411020 12/16 (75%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.