Protein Alignment: Ca-beta and cacnb1

• Sequence 1: NP_001260375.1
• Gene: Ca-beta
• FlyBaseID: FBgn0259822
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: XP_005163864.2
• Gene: cacnb1
• ZFINID: ZDB-GENE-040718-399
• Length: 645
• Species: Danio rerio
• Alignment Length: 660
• Identity: 326/661 (49%)
• Similarity: 398/661 (60%)
• Gaps: 93/661 (14%)

  Fly     1 MVQRASSSDAPSV-----------QGGQH-------RESRF--GLGYPSYQSGYNKLFTQGSADS 45
            |||..:.|..||.           ..|.|       |:|||  ..|..|..:..|....||||||
Zfish     1 MVQEGNMSRTPSTSTQEIQMDMFDHHGSHAQGKYAKRKSRFKRSDGSTSSDTTSNSFVRQGSADS 65

  Fly    46 NYSQPS-SDLSLDEEKESLRREKERQALSQLDKARSKPVAFAVRTNVAYDGAIDDDSPVQGGAVS 109
            ..|:|| ||:||:|:.|:||:|.:||||:.|:||::|||||||||||.|:...:||.||||.|:|
Zfish    66 YTSRPSDSDVSLEEDPEALRKEADRQALATLEKAKTKPVAFAVRTNVGYNPGPNDDVPVQGMAIS 130

  Fly   110 FEIREFLHIKEKYDNNWWIGRLVKEGCDVGFIPSPAKLDNIR--MQNQTRPSRLYGTKGSSSGNL 172
            ||.::||||||||:|:|||||||||||:|||||||.||::.|  .:.:.|.:||..:|
Zfish   131 FEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLESTRQLQEQRMRQNRLSSSK------- 188

  Fly   173 GAGGQAGAEPSRGSTPPTP------------------------GDESDSMGPGRHGKTPAAAANK 213
             :||.:..:.:.|:..|||                        .|..|..|.|  |...:...|.
Zfish   189 -SGGSSSLDVATGARRPTPPGTADLSSGLYDDALDSDVEEAETADTRDHKGVG--GSVTSPQGNL 250

  Fly   214 EKRKPFFKKQETASPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRIIITRVMAD 278
             .|.|||||.|...||||||||||::|||||||||||||||||||||||||:|||||.||||.||
Zfish   251 -PRLPFFKKMEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHKFEGRISITRVTAD 314

  Fly   279 ISLAKRSIMNNPSKRAIMERSSSRS--DCLGKVQEEIERIFELARSLQLVVLDCDTINHPSQLAK 341
            |||||||::|||||..|:||||:||  |.|.:||.||||||||||:||||.||.|||||||||||
Zfish   315 ISLAKRSVLNNPSKHTIIERSSTRSSLDLLAEVQSEIERIFELARTLQLVALDADTINHPSQLAK 379

  Fly   342 TSLAPTIVYLKISSSKVLQRLIKSRGKSQAKNLSVQMVAAEKLAQCPPDMFDVILDENQLEDACE 406
            |||||.|||:||:|.||||||||||||||||:|:||||||:|||||||::||:||||||||||||
Zfish   380 TSLAPIIVYIKIASPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDIILDENQLEDACE 444

  Fly   407 HIAEYLETYWKATHPDIRAVP-PIARPLPQEASPSADPARLGPTPPVDGEEFV-DEQDPRMGMSG 469
            |:|||||.|||||||.....| |:.......|:.:|.|.   |...:.|...| .||...|...|
Zfish   445 HLAEYLEAYWKATHPPSSNPPNPLLNRTMATAALAASPE---PVSNLQGPFLVHGEQKREMPERG 506

  Fly   470 G------DREGSRERDRDSRERERERER---ERDYWDREFNRDRSS---KDRERDLEWERERARE 522
            |      |..| ::..|.||.:.:...|   .:|.:|.|....|.|   .|.|.|...|.:..|.
Zfish   507 GLQDYQSDLSG-KQPLRSSRSQLQTGSRGLSRQDTFDSETQGSRDSAYTDDMETDPYEEPDPCRS 570

  Fly   523 WERERERDWDREFDW-DQGGTSYQHSRRQ--PTSVRHQERGGG-------VGAGGGGGGVGGGYE 577
            :.........|:..| |:|....|.:...  |.:.:|| ||.|       ..|..||...|
Zfish   571 YRLNPAHHAPRQASWEDEGAEPDQENLNMVPPPANQHQ-RGRGKLRERYCQDAEAGGATTG---- 630

  Fly   578 RDRERERYER 587
            |:..:|.:.|
Zfish   631 RNHNQEEWSR 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ca-beta	NP_001260375.1	VGCC_beta4Aa_N	41..81	CDD:288872	24/41 (59%)
		SH3_CACNB	85..146	CDD:212797	45/61 (74%)
		Guanylate_kin	234..415	CDD:279019	151/183 (83%)
		NK	244..416	CDD:302627	144/174 (83%)
cacnb1	XP_005163864.2	VGCC_beta4Aa_N	61..102	CDD:288872	24/41 (59%)
		SH3_CACNB1	102..169	CDD:212974	51/67 (76%)
		Guanylate_kin	270..453	CDD:279019	151/183 (83%)
		NK	280..454	CDD:302627	144/174 (83%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C52591376
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	507	1.000	Inparanoid score	I1266
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0000450
OrthoInspector	1	1.000				T596145
orthoMCL	1	0.900				OOG5_128949
Panther	1	1.100			LDO	PTHR11824
Phylome	1	0.910		0.778	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R3437
TreeFam	1	0.960
ZFIN	0	0.000	Not matched by this tool.
	10	9.880