Protein Alignment Ca-beta and ccb-2

DIOPT Version :10

• Sequence 1: NP_001260375.1
• Gene: Ca-beta / 34557
• FlyBaseID: FBgn0287724
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_001293380.1
• Gene: ccb-2 / 189330
• WormBaseID: WBGene00021125
• Length: 396
• Species: Caenorhabditis elegans
• Alignment Length: 397
• Identity: 97/397 - (24%)
• Similarity: 180/397 - (45%)
• Gaps: 84/397 - (21%)

  Fly    46 NYSQPSSDLSLDEEKESLRREKERQ------ALSQLDKARSKPVAFAVRTNVAYDGAIDDDSPVQ 104
            :|...|::..:.....|.|.::.|:      ||..|..::.|.|||||:....|||::|:.||::
 Worm    54 SYKLSSNEPGIKLMHNSQRDDQHRKDVEHFAALRALQHSKRKHVAFAVQAMRDYDGSLDEKSPLK 118

  Fly   105 GGAVSFEIREFLHIKEKYDNNWWIGRLVKEGCDVGFIPSPAKLDNIRMQNQTRPSRLYGTKGSSS 169
            ...:||...:|:||..|::::|||||:|:...:.||:|:..:|.|..:.::
 Worm   119 DHTISFNTNDFIHIHTKFNSDWWIGRIVRSHSEFGFVPTARRLANYMVSDE-------------- 169

  Fly   170 GNLGAGGQAGAEPSRGSTPPTPGDESDSMGPGRHGKTPAAAANKEKRKPFFKKQETASPYDVVPS 234
                             .||...:.||                .:.|..:    |...||.||||
 Worm   170 -----------------DPPVKHNTSD----------------HQDRSIW----EPKCPYKVVPS 197

  Fly   235 MRPVVLVGPSLKGYEVTDMMQKAL-FDFLKHRFEGRIIITRVMADISLAKRSIMNNPSK--RAIM 296
            .||:||:||:|:...:|.::..|| .:.|||..:.   :..|.:||...::|.....::  |.:.
 Worm   198 SRPIVLLGPTLQHSRLTQLLHLALREEILKHFGKN---MKYVKSDIGSGQQSGDRKGARWLRGLR 259

  Fly   297 ERSSSRSDCLGKVQEEIERIFELARSLQLVVLDCDTINHPSQLAKTSLAPTIVYLKISSSKVLQR 361
            :....:.:     .:|:|.|..:...|.|:::|...|:.|..:....|:|....:::|.:|:|.:
 Worm   260 DYDRGQDE-----NQEVELIMRMTSKLHLLLVDSPHIHTPDDVQHLPLSPIFFLIRVSDNKILAK 319

  Fly   362 LIKSRGKSQAKNLSVQMVAAEKLAQCPPDM-------------FDVILDENQLEDACEHIAEYLE 413
            |:::.|.::   ::.::..|..|.....|.             |:::::||.|.:|...|..|||
 Worm   320 LLRNTGTTR---MAAEIEVANVLKTMNDDRVGGHDDEQLIARGFEMVIEENGLREATRRIISYLE 381

  Fly   414 TYWKATH 420
            .|..|.|
 Worm   382 KYIHALH 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ca-beta	NP_001260375.1	VGCC_beta4Aa_N	41..81	CDD:463445	8/40 (20%)
		SH3_CACNB	85..146	CDD:212797	24/60 (40%)
		Guanylate_kin	234..415	CDD:395500	46/196 (23%)
ccb-2	NP_001293380.1	SH3_CACNB	99..160	CDD:212797	24/60 (40%)