Protein Alignment: Ca-beta and Cacnb4

• Sequence 1: NP_001260375.1
• Gene: Ca-beta
• FlyBaseID: FBgn0259822
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_001032176.1
• Gene: Cacnb4
• MGIID: 103301
• Length: 519
• Species: Mus musculus
• Alignment Length: 567
• Identity: 294/568 (52%)
• Similarity: 369/568 (65%)
• Gaps: 76/568 (13%)

  Fly     5 ASSSDAPSVQ---GGQHRESRFGLGYPSYQSGYNKLFTQGSADSNYSQPS-SDLSLDEEKESLRR 65
            |....:||.|   |...|.||......|..| .:.:..||||||..|:|| ||:||:|::|::|:
Mouse    11 ADGPHSPSSQVARGTTTRRSRLKRSDGSTTS-TSFILRQGSADSYTSRPSDSDVSLEEDREAIRQ 74

  Fly    66 EKERQALSQLDKARSKPVAFAVRTNVAYDGAIDDDSPVQGGAVSFEIREFLHIKEKYDNNWWIGR 130
            |:|:||..||::|:||||||||:|||:|.||:|:|.||...|:||:.::||||||||:|:|||||
Mouse    75 EREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGR 139

  Fly   131 LVKEGCDVGFIPSPAKLDNIRMQNQTRPSRLYGTKGSSSGNLGAGGQAGAEPSRGSTPPTPGDES 195
            ||||||::||||||.:|:|||:|.:.:..|.:|  |.||||                      .|
Mouse   140 LVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHG--GKSSGN----------------------SS 180

  Fly   196 DSMG---PGRHGKTPAAAANKEKRKPFFKKQETASPYDVVPSMRPVVLVGPSLKGYEVTDMMQKA 257
            .|:|   .|....||...| |:|:    |..|...||||||||||||||||||||||||||||||
Mouse   181 SSLGEMVSGTFRATPTTTA-KQKQ----KVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKA 240

  Fly   258 LFDFLKHRFEGRIIITRVMADISLAKRSIMNNPSKRAIMERSSSRSDCLGKVQEEIERIFELARS 322
            |||||||||:|||.||||.|||||||||::||||||||:|||::||. |.:||.|||||||||||
Mouse   241 LFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSS-LAEVQSEIERIFELARS 304

  Fly   323 LQLVVLDCDTINHPSQLAKTSLAPTIVYLKISSSKVLQRLIKSRGKSQAKNLSVQMVAAEKLAQC 387
            |||||||.||||||:||.||||||.||::|:||.||||||||||||||:|:|:||:|||:|||||
Mouse   305 LQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQC 369

  Fly   388 PPDMFDVILDENQLEDACEHIAEYLETYWKATHPDIRAVPPIARPLPQEASPSADPARLGPTPPV 452
            ||:|||||||||||||||||:.||||.||:|||..  :..|:...|.:....:|    |.|.|
Mouse   370 PPEMFDVILDENQLEDACEHLGEYLEAYWRATHTS--SSTPMTPLLGRNVGSTA----LSPYP-- 426

  Fly   453 DGEEFVDEQDPRMGMSGGDREGSRERDRDSRERERERERERDYWDREFNRDRSSKDRERDLEWER 517
                        ..:||...:..|..:..:.....|| |.....|..::.:|:.|.|.| |....
Mouse   427 ------------TAISGLQSQRMRHSNHSTENSPIER-RSLMTSDENYHNERARKSRNR-LSSSS 477

  Fly   518 ERAREWERERERDWDREFDWDQGGTSYQHSRRQPTSVRHQERG--GG 562
            :.:|:.....|.|:.         .|||.:.:.     |:.||  ||
Mouse   478 QHSRDHYPLVEEDYP---------DSYQDTYKP-----HRNRGSPGG 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ca-beta	NP_001260375.1	VGCC_beta4Aa_N	41..81	CDD:288872	23/41 (56%)
		SH3_CACNB	85..146	CDD:212797	42/61 (69%)
		Guanylate_kin	234..415	CDD:279019	151/181 (83%)
		NK	244..416	CDD:302627	142/172 (83%)
Cacnb4	NP_001032176.1	VGCC_beta4Aa_N	49..90	CDD:314861	23/41 (56%)
		SH3_CACNB4	90..157	CDD:212976	47/67 (70%)
		Guanylate_kin	217..397	CDD:331880	151/181 (83%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C52558662
eggNOG	1	0.900				E1_KOG3812
Hieranoid	1	1.000
Homologene	1	1.000				H20188
Inparanoid	1	1.050	511	1.000	Inparanoid score	I1297
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0000450
OrthoInspector	1	1.000				T615441
orthoMCL	1	0.900				OOG5_128949
Panther	1	1.100			O	PTHR11824
Phylome	1	0.910		0.889	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	1	0.960
	12	11.760