Protein Alignment: Ca-beta and Cacnb2

• Sequence 1: NP_001260375.1
• Gene: Ca-beta
• FlyBaseID: FBgn0259822
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: XP_017455922.1
• Gene: Cacnb2
• RGDID: 67385
• Length: 641
• Species: Rattus norvegicus
• Alignment Length: 618
• Identity: 315/619 (51%)
• Similarity: 397/619 (64%)
• Gaps: 79/619 (13%)

  Fly    35 NKLFTQGSADSNYSQPS-SDLSLDEEKESLRREKERQALSQLDKARSKPVAFAVRTNVAYDGAID 98
            :|..:.|||||..|:|| ||:||:|::|::|||.||||.:||:||::|||||||||||.|..|.:
  Rat    48 SKNVSWGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVRYSAAQE 112

  Fly    99 DDSPVQGGAVSFEIREFLHIKEKYDNNWWIGRLVKEGCDVGFIPSPAKLDNIRMQNQTR--PSRL 161
            ||.||.|.|:|||.::|||:|||::|:|||||||||||::||||||.||:|:|:|::.|  ..:.
  Rat   113 DDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKF 177

  Fly   162 YGTK--GSSSGNLGAGGQAGAEP-SRGSTPPTPGDESDSMG--------PGRHGKTPAAAAN--- 212
            |.:|  |:||.:||     ...| ||.||||:...:.|:.|        |..| ::|..:||
  Rat   178 YSSKSGGNSSSSLG-----DIVPSSRKSTPPSSAIDIDATGLDAEENDIPANH-RSPKPSANSVT 236

  Fly   213 ----KEKRKPFFKKQETASPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRIIIT 273
                ||||.|||||.|...|||||||||||||||||||||||||||||||||||||||||||.||
  Rat   237 SPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISIT 301

  Fly   274 RVMADISLAKRSIMNNPSKRAIMERSSSRSDCLGKVQEEIERIFELARSLQLVVLDCDTINHPSQ 338
            ||.|||||||||::|||||.||:|||::||. |.:||.||||||||||:|||||||.||||||:|
  Rat   302 RVTADISLAKRSVLNNPSKHAIIERSNTRSS-LAEVQSEIERIFELARTLQLVVLDADTINHPAQ 365

  Fly   339 LAKTSLAPTIVYLKISSSKVLQRLIKSRGKSQAKNLSVQMVAAEKLAQCPP-DMFDVILDENQLE 402
            |:||||||.|||:||||.||||||||||||||||:|:||||||:||||||| :.|||||||||||
  Rat   366 LSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPQESFDVILDENQLE 430

  Fly   403 DACEHIAEYLETYWKATHPDIRAVPP--IARPLPQEASPSADPARLGPTPPVDGEEFVDEQDPRM 465
            |||||:|:|||.|||||||....:|.  ::|.|.....| ..|.....:....|::..|...||
  Rat   431 DACEHLADYLEAYWKATHPPSSNLPNPLLSRTLATSTLP-LSPTLASNSQGSQGDQRTDRSAPR- 493

  Fly   466 GMSGGDREGSRERDRDSRERERERERE------------RDYWDREFNRDRSSKDRERDLEWERE 518
            ..|..:.|...|..:.|:.|......:            ::.:|.|....|.|...|...::..|
  Rat   494 SASQAEEEPCLEPVKKSQHRSSSATHQNHRSGTGRGLSRQETFDSETQESRDSAYVEPKEDYSHE 558

  Fly   519 RAREWERERERDWDREFDWDQGGTSYQHSRRQPTSVRHQERGGGVGAGGGGGGVGGGYERD---- 579
            ....:...||.:...|.....|     |..|:|   ||:.|..|               ||
  Rat   559 HVDRYVPHREHNHREESHSSNG-----HRHREP---RHRTRDMG---------------RDQDHN 600

  Fly   580 ---RERERYERRERDLMHYDLNSDELLDERNFE 609
               ::|.|::.::|    |.....|::.:|..|
  Rat   601 ECSKQRSRHKSKDR----YCDKEGEVISKRRSE 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ca-beta	NP_001260375.1	VGCC_beta4Aa_N	41..81	CDD:288872	25/41 (61%)
		SH3_CACNB	85..146	CDD:212797	42/61 (69%)
		Guanylate_kin	234..415	CDD:279019	153/182 (84%)
		NK	244..416	CDD:302627	144/173 (83%)
Cacnb2	XP_017455922.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C52564728
eggNOG	1	0.900				E1_KOG3812
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	514	1.000	Inparanoid score	I1228
OMA	1	1.010
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0000450
OrthoInspector	1	1.000				T617551
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR11824
Phylome	1	0.910		0.889	Consistency score
TreeFam	1	0.960
	10	9.860